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9781936113040

The Origins of Life

by ;
  • ISBN13:

    9781936113040

  • ISBN10:

    193611304X

  • Format: Hardcover
  • Copyright: 2010-06-28
  • Publisher: Cold Spring Harbor Laboratory Press

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Supplemental Materials

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Summary

Life arose on Earth more than three billion years ago. How the first self-replicating systems emerged from prebiotic chemistry and evolved into primitive cell-like entities is an area of intense research, spanning molecular and cellular biology, organic chemistry, cosmology, geology, and atmospheric science. Written and edited by experts in the field, this volume provides a comprehensive account of the environment of the early Earth and the mechanisms by which the organic molecules present may have self-assembled to form replicating material such as RNA and other polymers. The contributors examine the energetic requirements for this process and focus in particular on the essential role of semi-permeable compartments in containment of primitive genetic systems.

Table of Contents

Prefacep. vii
Introduction and Overviewp. 1
Historical Development of Origins Researchp. 5
Setting The Stage
Cosmic Carbon Chemistry: From the Interstellar Medium to the Early Earthp. 21
The Hadean-Archaean Environmentp. 35
Earth's Earliest Atmospheresp. 49
Components of First Life
Planetary Organic Chemistry and the Origins of Biomoleculesp. 67
The Organic Composition of Carbonaceous Meteorites: The Evolutionary Story Ahead of Biochemistryp. 89
Ribonucleotidesp. 109
The Origin of Biological Homochiralityp. 123
Primitive Systems
Bioenergetics and Life's Originsp. 141
Mineral Surfaces, Geochemical Complexities, and the Origins of Lifep. 157
From Self-Assembled Vesicles to Protocellsp. 179
Membrane Transport in Primitive Cellsp. 193
First Polymers
Primitive Genetic Polymersp. 207
Closing the Circle: Replicating RNA with RNAp. 229
The Origins of Cellular Lifep. 245
Transition to a Microbial World
Origin and Evolution of the Ribosomep. 261
Deep Phylogeny-How a Tree Can Help Characterize Early Life on Earthp. 279
Constructing Partial Models of Cellsp. 295
An Origin of Life on Marsp. 305
Indexp. 313
Table of Contents provided by Ingram. All Rights Reserved.

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