Practical Aspects of Trapped Ion Mass Spectrometry, Volume V: Applications of Ion Trapping Devices

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  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2009-11-11
  • Publisher: CRC Press

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Widely used in medical research, pharmaceutical and fine chemicals industries, biological and physical sciences, and security and environmental agencies, mass spectrometry techniques are continually under development. In Practical Aspects of Trapped Ion Mass Spectrometry: Volume V, Applications of Ion Trapping Devices,an international panel of authors presents a world-wide view of the practical aspects of recent progress using trapped ion devices. In contrast to previous texts, which have concentrated generally on a single or limited range of ion trapping techniques, a key feature of this compilation of contributions is its coverage of all the ion trapping techniques currently in use. Spanning sixteen chapters, the text examines: Ion/neutral and ion/ion reactions Structural characterization of proteins and peptides using quadrupole ion trap mass spectrometry, Fourier transform “ ion cyclotron resonance (FT-ICR) mass spectrometry, and traveling wave ion mobility mass spectrometry Ion spectroscopy and electron diffraction Conformational analysis of protein isobaric charge states Practical examples of trapped-ion technology that reflect the wide diversity of applications of trapped-ion devices This text is the first detailed account of the application of new and established mass spectrometric techniques utilizing trapped or confined ions for prolonged investigation and increased sensitivity. Each chapter contains complete references and utilizes a consistent format and writing style, with all terms, acronyms, procedures, and equations thoroughly explained. The strong editorial input to the diverse sections enables readers to readily appreciate the commonalities of topics ranging from theory of instrument operation to proteins, flavonoids, atomic clocks, and single ion mass spectrometry.

Table of Contents

Prefacep. xi
Volume IV Contentsp. xxi
Editorsp. xxv
Contributorsp. xxix
Ion Reactions
Ion/Ion Reactions in Electrodynamic Ion Trapsp. 3
Gas-Phase Hydrogen/Deuterium Exchange in Quadrupole-Ion Trapsp. 35
Methods for Multi-Stage Ion Processing Involving Ion/Ion Chemistry in a Quadrupole Linear Ion Trapp. 59
Ion Conformation and Structure
Chemical Derivatization and Multistage Tandem Mass Spectrometry for Protein Structural Characterizationp. 83
Fourier Transform Ion Cyclotron Resonance Mass Spectrometry in the Analysis of Peptides and Proteinsp. 121
MS/MS Analysis of Peptide-Polyphenols Supramolecular Assemblies: Wine Astringency Approached by ESI IT-MSp. 153
Structure and Dynamics of Trapped Ionsp. 169
Applications of Traveling Wave Ion Mobility-Mass Spectrometryp. 205
Ion Spectroscopy
The Spectroscopy of Ions Stored in Trapping Mass Spectrometersp. 239
Sympathetically-Cooled Single Ion Mass Spectrometryp. 291
Ion Trap: A Versatile Tool for the Atomic Clocks of the Future!p. 327
Practical Applications
Boundary-Activated Dissociations (BAD) in a Digital Ion Trap (DIT)p. 367
The Study of Ion/Molecule Reactions at Ambient Pressure with Ion Mobility Spectrometry and Ion Mobility/Mass Spectrometryp. 387
The Role of Trapped Ion Mass Spectrometry for Imagingp. 417
Technology Progress and Application in GC/MS and GC/MS/MSp. 439
Remote Monitoring of Volatile Organic Compounds in Water by Membrane Inlet Mass Spectrometryp. 491
Author Indexp. 509
Subject Indexp. 513
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