Psychotropic Drugs & Women PA

by Hendrick,Victoria

• ISBN13: 9780393704211
• ISBN10: 0393704211
• Edition: 00
• Format: Paperback
• Copyright: 2004-04-17
• Publisher: W. W. Norton & Company

Summary

Whereas potential risks of medication exposure during pregnancy had once been the key consideration when prescribing psychotropic drugs, research has shown that throughout a woman's life there are other no-less-important risks and reactions unique to the female physiology. Inside this book, readers will find extended discussions of the medication of depressive disorders, bipolar disorders, anxiety disorders, schizophrenia, and eating disorders. Key drug classes such as antidepressants, antipsychotics, anxiolytics, mood stabilizers, and stimulants are discussed throughout as they apply to these various disorders. There are also wide-ranging chapters addressing the general implications of female physiology on psychopharmacology as well as the female reproductive system and central nervous system. Bibliographies corresponding to each chapter point clinicians in the right direction when further research is required. As with other volumes in Norton's 'Fast Facts' series, Psychotropic Drugs and Women: Fast Facts presents all the critical information pertaining to prescription, cross-indication, and side effects, often in easy-to-read tables and charts. This handy guide is essential reading for all physicians and mental health professionals.

Author Biography

Michael Gitlin is Professor of Clinical Psychiatry and Director of the Adult Division, UCLA Department of Psychiatry.

Table of Contents

Abbreviations	xi
Preface	xiii
Acknowledgments	xv
1. General Considerations in the Psychopharmacological Treatment of Women	3	(18)
Introduction	3	(3)
The Use of Psychiatric Medications for Women of All Ages	6	(1)
The Use of Psychiatric Medications in Women of Reproductive Age	7	(2)
General Principles for Use of Psychotropic Medications During Pregnancy	9	(5)
General Principles for Use of Psychotropic Medications During Breast-Feeding	14	(3)
The Use of Psychiatric Medications for Peri- and Postmenopausal Women	17	(1)
The Use of Psychiatric Medications for Elderly Women	18	(3)
2. Gender Differences in Psychopharmacology	21	(10)
Introduction	21	(1)
Gender Differences in Pharmacokinetics of Medications	22	(1)
Gender Differences in Cytochrome P450 System	23	(1)
Effect of Menstrual Cycle on Drug Metabolism	24	(1)
Effect of Pregnancy on Drug Metabolism	24	(1)
Effect of Menopausal Status on Drug Metabolism	25	(1)
Drug Interactions	25	(6)
3. Depressive Disorders	31	(40)
Introduction	31	(4)
Antidepressants	35	(13)
Phases of Treatment	48	(1)
Treatment Considerations for Women of Reproductive Age	49	(1)
Treatment of Depression During Pregnancy	50	(8)
Pharmacological Treatment of Postpartum Depression	58	(1)
Use of Antidepressants During Breast-Feeding	59	(3)
Treatment Considerations for Peri- and Postmenopausal Women	62	(1)
Treatment Considerations for Elderly Women	63	(1)
Treatment-Resistant Depression	63	(8)
4. Bipolar Disorder	71	(36)
Introduction	71	(2)
Mood Stabilizers/Antimanic Agents	73	(17)
Phases of Treatment	90	(2)
Treatment Considerations for Women of Reproductive-Age	92	(2)
Treatment of Bipolar Disorder During Pregnancy	94	(6)
Treatment of Bipolar Disorder Following Delivery	100	(1)
Use of Mood Stabilizers During Breast-Feeding	101	(3)
Treatment Considerations for Peri- and Postmenopausal Women	104	(1)
Treatment Considerations for Elderly Women	104	(1)
Bipolar Depression	105	(2)
5. Anxiety Disorders and Insomnia	107	(24)
Introduction	107	(2)
Pharmacological Treatment of Anxiety Disorders	109	(13)
Treatment Considerations for Women of Reproductive Age	122	(1)
Treatment of Anxiety Disorders During Pregnancy	123	(2)
Treatment of Anxiety Disorders During Breast-Feeding	125	(1)
Treatment Considerations for Peri- and Postmenopausal Women	126	(1)
Treatment Considerations for Elderly Women	126	(1)
Treatment of Insomnia	126	(5)
6. Schizophrenia	131	(26)
Introduction	131	(2)
Antipsychotic Agents	133	(14)
Phases of Treatment	147	(1)
Treatment Considerations for Women of Reproductive Age	148	(1)
Treatment of Schizophrenia During Pregnancy	149	(4)
Treatment of Schizophrenia During Breast-Feeding	153	(1)
Treatment Considerations for Peri- and Postmenopausal Women	154	(1)
Treatment Considerations for Elderly Women	155	(1)
Strategies for Treatment Resistance	155	(2)
7. Premenstrual Dysphoric Disorder	157	(10)
Introduction	157	(1)
Evaluation of Women Presenting with Premenstrual Dysphoric Disorder	158	(2)
Treatments for Premenstrual Dysphoric Disorder	160	(7)
8. Eating Disorders	167	(10)
Introduction	167	(2)
Treatment of Anorexia and Bulimia Nervosa	169	(1)
Pharmacological Treatments for Bulimia Nervosa and Binge-Eating Disorder	170	(2)
Pharmacological Treatments for Anorexia Nervosa	172	(1)
Treatment of Eating Disorders During Pregnancy	173	(1)
Treatment of Eating Disorders Following Delivery	174	(3)
9. Female Reproductive Hormones and the Central Nervous System	177	(10)
Review of Female Endocrinology	177	(3)
Hormone Supplementation	180	(2)
Hormones and Mood	182	(5)
Appendix 1. Drug Identification by Generic Name	187	(4)
Appendix 2. Drug Identification by Brand Name	191	(4)
Bibliography	195	(24)
Index	219