Pulmonary Physiology, Seventh Edition

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  • Edition: 7th
  • Format: Paperback
  • Copyright: 2007-01-09
  • Publisher: McGraw-Hill Medical
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Understanding pulmonary physiology begins with a solid emphasis on essential concepts. And that's exactly the base of knowledge that you'll get from Pulmonary Physiology. Through six successful editions, this well-illustrated, concise, yet complete text has immersed medical students and residents in all the critical topics of this demanding discipline-from the mechanics of breathing to the respiratory system under stress. Learning objectives are clearly mapped out for each chapter, which then promotes self-instruction of the material. And when it comes time to test your knowledge, clinical problems prompt you to apply what you've learned to realistic clinical scenarios.

Author Biography

Michael G. Levitzky, PhD, Professor of Physiology and Anesthesiology at Louisiana State University Medical Center.

Table of Contents

Prefacep. ix
Function & Structure of the Respiratory Systemp. 1
Objectivesp. 1
Functions of the Respiratory Systemp. 2
Structure of the Respiratory Systemp. 4
Key Conceptsp. 10
Suggested Readingsp. 10
Mechanics of Breathingp. 11
Objectivesp. 11
Generation of a Pressure Gradient Between Atmosphere & Alveolip. 12
Pressure-Volume Relationships in the Respiratory Systemp. 20
Interaction of Lung & Chest Wall: The Static Pressure-Volume Curvep. 29
Airways Resistancep. 32
The Work of Breathingp. 49
Key Conceptsp. 50
Clinical Problemsp. 51
Suggested Readingsp. 52
Alveolar Ventilationp. 54
Objectivesp. 54
The Lung Volumesp. 54
Measurement of the Lung Volumesp. 57
Anatomic Dead Space & Alveolar Ventilationp. 65
Measurement of Alveolar Ventilationp. 67
Alveolar Ventilation & Alveolar Oxygen & Carbon Dioxide Levelsp. 71
Regional Distribution of Alveolar Ventilationp. 75
The Closing Volumep. 79
The Effects of Agingp. 81
Key Conceptsp. 82
Clinical Problemsp. 83
Suggested Readingsp. 84
Blood Flow to the Lungp. 86
Objectivesp. 86
The Bronchial Circulationp. 87
The Functional Anatomy of the Pulmonary Circulationp. 89
Pulmonary Vascular Resistancep. 92
The Regional Distribution of Pulmonary Blood Flow: The Zones of the Lungp. 99
Hypoxic Pulmonary Vasoconstrictionp. 105
Pulmonary Edemap. 108
Key Conceptsp. 111
Clinical Problemsp. 111
Suggested Readingsp. 112
Ventilation-Perfusion Relationshipsp. 113
Objectivesp. 113
The Concept of Matching Ventilation & Perfusionp. 113
Consequences of High & Low V/Qp. 114
Testing for Nonuniform Distribution of Inspired Gas & Pulmonary Blood Flowp. 116
Regional V/Q Differences & Their Consequences in the Lungp. 125
Key Conceptsp. 128
Clinical Problemsp. 128
Suggested Readingsp. 129
Diffusion of Gasesp. 130
Objectivesp. 130
Fick's Law for Diffusionp. 130
Limitations of Gas Transferp. 133
Diffusion of Oxygenp. 135
Diffusion of Carbon Dioxidep. 137
Measurement of Diffusing Capacityp. 137
Key Conceptsp. 140
Clinical Problemsp. 140
Suggested Readingsp. 141
The Transport of Oxygen & Carbon Dioxide in the Bloodp. 142
Objectivesp. 142
Transport of Oxygen by the Bloodp. 142
Hemoglobin & the Physiologic Implications of the Oxyhemoglobin Dissociation Curvep. 145
Influences on the Oxyhemoglobin Dissociation Curvep. 148
Transport of Carbon Dioxide by the Bloodp. 156
The Carbon Dioxide Dissociation Curvep. 158
The Bohr & Haldane Effects Explainedp. 159
Key Conceptsp. 161
Clinical Problemsp. 161
Suggested Readingsp. 162
The Regulation of Acid-Base Statusp. 163
Objectivesp. 163
The Chemistry of Acids, Bases, & Buffersp. 163
Buffer Systems of the Human Bodyp. 166
Acidosis & Alkalosisp. 171
Respiratory & Renal Compensatory Mechanismsp. 176
Clinical Interpretation of Blood Gases & Acid-Base Statusp. 178
The Causes of Hypoxiap. 181
Key Conceptsp. 184
Clinical Problemsp. 185
Suggested Readingsp. 188
The Control of Breathingp. 189
Objectivesp. 189
The Generation of Spontaneous Rhythmicityp. 191
The Medullary Respiratory Centerp. 192
The Pontine Respiratory Groupp. 194
Spinal Pathwaysp. 195
Reflex Mechanisms of Respiratory Controlp. 195
Influences of Higher Centersp. 201
The Response to Carbon Dioxidep. 202
The Response to Hydrogen Ionsp. 209
The Response to Hypoxiap. 210
The Response to Exercisep. 211
Key Conceptsp. 213
Clinical Problemsp. 214
Suggested Readingsp. 215
Nonrespiratory Functions of the Lungp. 216
Objectivesp. 216
Pulmonary Defense Mechanismsp. 216
Nonrespiratory Functions of the Pulmonary Circulationp. 222
Metabolic Functions of the Lungp. 224
Key Conceptsp. 227
Suggested Readingsp. 227
The Respiratory System Under Stressp. 228
Objectivesp. 228
Exercise & the Respiratory Systemp. 228
Altitude & Acclimatizationp. 234
Diving & the Respiratory Systemp. 240
Key Conceptsp. 247
Clinical Problemsp. 247
Suggested Readingsp. 248
Clinical Problem Answersp. 250
Appendixp. 263
Symbols Used in Respiratory Physiologyp. 263
The Laws Governing the Behavior of Gasesp. 263
Frequently Used Equationsp. 264
Pulmonary Function Test Decision Treep. 265
Table of Normal Respiratory and Circulatory Valuesp. 266
General Suggested Readingsp. 266
Indexp. 267
Table of Contents provided by Ingram. All Rights Reserved.

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