Rang & Dale's Pharmacology

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  • Edition: 7th
  • Format: Paperback
  • Copyright: 2011-05-04
  • Publisher: Elsevier Science Health Science
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Rang & Dale's Pharmacology provides you with all the knowledge you need to get through your pharmacology course and beyond. Drs. Humphrey P. Rang, Maureen M. Dale, James M. Ritter, Rod Flower, and Graeme Henderson present a clear and accessible approach to the analysis of therapeutic agents at the cellular and molecular level through detailed diagrams, full-color illustrations, and pedagogical features. Plus, USMLE-style review questions and additional learning tools online at studentconsult.com make this the perfect resource to turn to for a full understanding of key concepts in pharmacology. Access the fully searchable text online at studentconsult.com, along with 500 USMLE-style multiple-choice review questions, downloadable images, and online only references. Find and cross-reference information quickly using a color-coded layout that makes navigation easy. Effectively understand and review key concepts through detailed diagrams and full-color illustrations that clarify even the most complex concepts. Reinforce your learning with key points boxes and clinical uses boxes that highlight crucial information and clinical applications. Apply current best practices and clinical applications through thoroughly updated and revised drug information. Stay current with the latest developments in the field thanks to major updates in chapters such as How Drugs Act; Amino Acid Transmitters; Analgesic Drugs; Antidepressant Drugs; and Drug Addiction, Dependence & Abuse. Tap into comprehensive content tailored to your courses with new and reorganized chapters on Host Defense; Inflammatory Mediators; Pharmacogenetics, Pharmacogenomics & Personalized Medicine; Hydroxytoptomine & The Pharmacy of Migraine; and Purines. Build your basic and clinical pharmacology knowledge with a comprehensive yet easy-to-use text

Table of Contents

General principles
What is pharmacology?
How drugs act: general principles
How drugs act: molecular aspects
How drugs act: cellular aspects-excitation, contraction and secretion
Cell proliferation, apoptosis, repair and regeneration
Cellular mechanisms: host defence
Method and measurement in pharmacology
Drug absorption and distribution
Drug metabolism and elimination
Pharmacogenetics, pharmacogenomics and 'personalised medicine'
Chemical mediators
Chemical mediators and the autonomic nervous system
Cholinergic transmission
Noradrenergic transmission
5-Hydroxytryptamine and the pharmacology of migraine
Local hormones: cytokines, biologically active lipids, amines and peptides
Peptides and proteins as mediators
Nitric oxide
Drugs affecting major organ systems
The heart
The vascular system
Atherosclerosis and lipoprotein metabolism
Haemostasis and thrombosis
Haemopoietic system and treatment of anaemia
Anti-inflammatory and immunosuppressant drugs
The respiratory system
The kidney
The gastrointestinal tract
The control of blood glucose and drug treatment of diabetes mellitus
The pituitary and the adrenal cortex
The thyroid
The reproductive system
Bone metabolism
The nervous system
Chemical transmission and drug action in the central nervous system
Amino acid transmitters
Other transmitters and modulators
Neurodegenerative diseases
General anaesthetic agents
Analgesic drugs
Local anaesthetics and other drugs affecting sodium channels
Anxiolytic and hypnotic drugs
Antiepileptic drugs
Antipsychotic drugs
Antidepressant drugs
CNS stimulants and psychotomimetic drugs
Drug addiction, dependence and abuse
Drugs used for the treatment of infections, cancer and immunological disorders
Basic principles of antimicrobial chemotherapy
Antibacterial drugs
Antiviral drugs
Antifungal drugs
Antiprotozoal drugs
Anthelminthic drugs
Anticancer drugs
Special topics
Individual variation and drug interaction
Harmful effects of drugs
Lifestyle drugs and drugs in sport
Biopharmaceuticals and gene therapy
Drug discovery and development
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