9780763727475

Tightly organized into a super-condensed outline bulleted format, this handy, pocket-sized manual details precise, up-to-date information for diagnosis and treatment of Prostate Cancer. Throughout the book, tables and figures summarize important clinical data and current professional society recommendations, while salient references direct readers to additional information. Current, quick, and concise, For instant access on the ward or in the clinic!

Editor's Preface	p. ix
Preface	p. xi
Acknowledgments	p. xiii
Introduction	p. 1
Basic Principles	p. 3
The Anatomy of the Prostate Gland	p. 3
Function of the Prostate Gland	p. 5
Epidemiology of Prostate Cancer	p. 5
Prevention of Prostate Cancer	p. 9
Prostate Cancer Screening	p. 11
Prostate Cancer Clinical States and Transitions	p. 15
References	p. 16
Clinical State: No Cancer Diagnosis	p. 19
The Diagnosis of Prostate Cancer	p. 21
Introduction	p. 21
History	p. 21
General Physical Examination	p. 23
Digital Rectal Examination (DRE)	p. 23
PSA	p. 25
New Serological Tests for Prostate Cancer	p. 31
Transrectal Ultrasonography (TRUS)	p. 31
Indications for TRUS-Guided Biopsy	p. 31
TRUS-Guided Biopsy	p. 32
TRUS Biopsy-Sampling	p. 33
Repeat Prostate Biopsy	p. 34
ASAP	p. 35
High-Grade PIN (HGPIN)	p. 35
Summary	p. 36
References	p. 36
Pathology of Prostate Cancer	p. 39
Histologic Types	p. 39
Tumor Grade (Adenocarcinoma)	p. 41
Additional Pathologic Findings	p. 42
Role of Pathology in Prostate Cancer Risk Assessment	p. 44
References	p. 44
Clinical State: Localized Disease	p. 45
Staging and Risk Assessment	p. 47
Introduction	p. 47
Staging	p. 48
Risk Assessment	p. 56
References	p. 60
Primary Management of Favorable- and Intermediate-Risk Prostate Cancer	p. 63
Introduction	p. 63
The Initial Management Consultation	p. 64
Surgical Approaches to Clinically Localized Prostate Cancer	p. 64
External-Beam Radiotherapy (EBRT)	p. 79
Brachytherapy	p. 89
EBRT Plus Brachytherapy	p. 95
High Dose Rate (HDR) Temporary Brachytherapy	p. 97
Miscellaneous Nonsurgical Approaches to Localized Prostate Cancer	p. 96
Noncurative Approaches to Localized Prostate Cancer	p. 97
Low- and Intermediate-Risk Prostate Cancer Primary Management Summary	p. 102
References	p. 104
Management of High-Risk Prostate Cancer-Adjuvant and Neoadjuvant Strategies	p. 111
Introduction	p. 111
Definition	p. 111
Adjuvant/Neoadjuvant Strategies for Patients Undergoing Surgical Prostatectomy	p. 113
Neoadjuvant Hormone Therapy Prior to Prostatectomy	p. 113
Neoadjuvant Chemotherapy Prior to Prostatectomy	p. 114
Adjuvant Chemotherapy After Prostatectomy	p. 115
Adjuvant Hormone Therapy After Prostatectomy	p. 116
Adjuvant Radiotherapy After Prostatectomy	p. 117
Neoadjuvant/Adjuvant Strategies for Patients Undergoing Radiotherapy	p. 119
Neoadjuvant Chemotherapy Prior to Radiotherapy	p. 119
Neoadjuvant or Adjuvant Hormone Therapy and Radiotherapy	p. 119
Summary and Conclusions Regarding Adjuvant/Neoadjuvant Therapy	p. 126
References	p. 127
Clinical State: Rising PSA	p. 131
Biochemical Failure and Salvage Therapy	p. 133
Introduction	p. 133
Summary and Conclusions, Biochemical Relapse and Salvage Therapy	p. 145
References	p. 147
Clinical States: Castrate and Noncastrate Metastatic Disease	p. 149
Hormone Therapy of Prostate Cancer	p. 151
Introduction	p. 151
Background	p. 151
Controversies in Hormone Therapy	p. 164
Complications of ADT	p. 168
Summary and Practical Use of ADT	p. 172
The Transition to the Castrate Metastatic State	p. 174
References	p. 174
Treatment of Castrate Metastatic Prostate Cancer (CMPC)	p. 179
Introduction	p. 179
Definition of Castrate Metastatic State	p. 179
Chemotherapy	p. 180
High-Grade Tumors and Unusual Histologic Forms	p. 191
Additional Approaches to Patients with CMPC	p. 191
Palliative EBRT	p. 194
Systemic Radiopharmaceuticals	p. 196
Surgery	p. 198
Nonspecific Measures	p. 198
Treatment of General Symptoms of Advanced CMPC	p. 198
Investigational Therapy	p. 200
Complementary Therapy for Prostate Cancer	p. 204
Summary and Conclusions, Treatment of CMPC	p. 205
References	p. 206
Selected Complications of Advanced Prostate Cancer	p. 213
Introduction	p. 213
Neuropsychiatric Complications	p. 213
Hematologic Complications	p. 221
Renal and Urologic Complications	p. 226
Metaholic/Endocrine Complications-Hypocalcemia	p. 230
Vascular Complications of Prostate Cancer	p. 231
References	p. 232
Index	p. 235
Table of Contents provided by Ingram. All Rights Reserved.

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