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9781588294760

Bioarrays

by ;
  • ISBN13:

    9781588294760

  • ISBN10:

    1588294765

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2007-06-27
  • Publisher: Humana Pr Inc

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Supplemental Materials

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Summary

Bioarrays: From Basics to Diagnostics provides an integrated and comprehensive collection of timely articles on the use of bioarray techniques in the fields of biotechnology and molecular medicine. The entire volume is broken into four sections a?? Bioarray Technology Platforms, Biomarkers and Clinical Genomics, Biomarker Identification Using Clinical Proteomics and Glycomics, and Emerging Technologies in Diagnostics a?? that create one well-integrated work. Particular emphasis is placed on DNA, protein, and carbohydrate biochips. The volume also looks extensively at oligonucleotides, cDNA, proteins, antibodies, and carbohydrate arrays. Bioarrays: From Basics to Diagnostics will serve as an indispensable reference for graduate students, post-docs, and professors as well as an explanatory analysis for executives and scientists in biotechnology and pharmaceutical companies.

Table of Contents

Forewordp. vii
Prefacep. ix
Contributorsp. xv
Bioarray Technology Platforms
Investigation of Tumor Metastasis by Using cDNA Microarraysp. 3
From Tissue Samples to Tumor Markersp. 17
Experimental Design for Gene Expression Analysis: Answers Are Easy, Is Asking the Right Question Difficult?p. 29
From Microarrays to Gene Networksp. 45
Biomarkers and Clinical Genomics
Reduction in Sample Heterogeneity Leads to Increased Microarray Sensitivityp. 61
Genomics to Identify Biomarkers of Normal Brain Agingp. 83
Gene Expression Profiling for Biomarker Discoveryp. 95
Array-Based Comparative Genomic Hybridization: Applications in Cancer and Tuberculosisp. 107
Regional Specialization of Endothelial Cells as Revealed by Genomic Analysisp. 123
Biomarker Identification by Using Clinical Proteomics and Glycomics
Identification of Target Antigens in CNS Inflammation by Protein Array Techniquep. 137
Differential Protein Expression, Protein Profiles of Human Gliomas, and Clinical Implicationsp. 149
Antibody-Based Microarrays: From Focused Assays to Proteome-Scale Analysisp. 175
Glycoprofiling by DNA Sequencer-Aided Fluorophore-Assisted Carbohydrate Electrophoresis: New Opportunities in Diagnosing and Following Diseasep. 191
High-Throughput Carbohydrate Microarray Technologyp. 201
Emerging Technologies in Diagnostics
Microarrays and Blood Diagnosticsp. 215
"Lab-On-A-Chip" Devices for Cellular Arrays Based on Dielectrophoresisp. 231
Genetic Disorders and Approaches to Their Preventionp. 245
Indexp. 263
Table of Contents provided by Ingram. All Rights Reserved.

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