Skin Aging, Free Radicals and Antioxidants

by Poljsak, Borut

• ISBN13: 9781613247181
• ISBN10: 1613247184
• Edition: 1st
• Format: Hardcover
• Copyright: 2012-03-01
• Publisher: NOVA SCIENCE PUBLISHERS INC

Summary

This book describes mechanisms of skin damage generation and examines the potential impact of free radicals, reactive oxygen species (ROS) and oxidative damage on the skin ageing process. It also evaluates methods to decrease skin oxidative stress, oxidative damage, and skin ageing. The identification of free radical reactions as promoters of the skin ageing process implies that interventions aimed at limiting or inhibiting free radical reactions should be able to reduce the rate of formation of ageing-related changes with a consequent reduction of the ageing rate. This book highlights how ageing of the skin happens, as well as what are the causes and the best ways to prevent and treat it.

Table of Contents

Preface	p. vii
The Consequence: Aging Process
Introduction and Description of the Problem	p. 1
What Is Aging?	p. 7
The Cause: Free radicals, Reactive Oxygen Species (ROS) and Oxidative Stress
The Role of Oxidative Stress on the General Aging Process	p. 19
Basic Information about the Skin	p. 31
General Overview of Skin Aging: The Role of Extrinsic (External) and Intrinsic (Free Radical Mediated Internal) Factors	p. 39
Mechanisms of Skin UV and Photoaging	p. 67
Skin, Free Radicals and Antioxidants	p. 113
General Overview of Antioxidative Protection	p. 115
The Act: Measures to Decrease Oxidative Stress
Antioxidant Prevention of Damage Induced by Extrinsic Factors (Environmental Pollutants)	p. 167
Decreasing Oxidative Stress Caused by Endogenous (Intrinsic) Factors-The Use of Antioxidants
Can Antioxidants as Dietary Supplements Offer Appropriate Protection against ROS-Induced Damage?	p. 175
Decreasing the Formation of Endogenous Oxidative Stress-Preventing the Formation of Free Radicals
Methodology for the Detection of Oxidative State in Biological Systems	p. 191
Alternative Methods to Decrease Oxidative Stress and Retard the Aging Process	p. 199
The Role of Telomeres in Skin Aging	p. 259
Hormones and Skin Aging	p. 263
Topical Treatment of Skin Aging	p. 271
Skin Curative Approaches	p. 289
Conclusion	p. 295
References	p. 311
Index	p. 387
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