Stereochemistry

by Morris, David G.

• ISBN13: 9780471224778
• ISBN10: 0471224774
• Edition: 1st
• Format: Paperback
• Copyright: 2002-05-09
• Publisher: Wiley-RSC

Summary

Stereochemistry covers the fundamental principles in all aspects of stereochemistry. This concise resource is generously enriched with numerous worked examples. Concentrating on organic chemistry, early chapters in this resourceful publication deal mainly with definitions of terms such as chirality, enantiomers, diastereoisomers and racemisation, complete with suitable examples to illustrate key concepts. Use of a polarimeter and associated definitions are described, together with two different conventions D, L and R, S for specification of configuration. The distinction between conformation and configuration is developed to include assignment onf configurations to di-substituted cyclohexanes and to the decalins.

Table of Contents

1. Simple Molecules: Hybridization, Conformation aand Configuration.

2. Chiral Molecules: One Stereogenic Centre.

3. Molecules with Two (or More) Stereogenic Centres.

4. Stereochemistry of Carbon-Carbon and Carbon-Nitrogen Double Bonds.

5. Chirality Without Stereogenic Carbon.

6. Stereoisomerism in Cyclic Structures.

7. Substitution Reactions at Saturated Carbon.

8. Prochirality, Enantiotopic and Diastereotopic Groups and Faces: Use of NMR Spectroscopy in Stereochemistry.

Answers to Problems.

Subject Index.