Synthetic Biology : Industrial and Environmental Applications

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  • Format: Hardcover
  • Copyright: 2012-08-20
  • Publisher: Wiley-Blackwell
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This is the only book to focus on industrial and environmental applications of synthetic biology, covering 17 of the most promising uses in the areas of biofuel, bioremediation and biomaterials. The contributions are written by experts from academia, non-profit organizations and industry, outlining not only the scientific basics but also the economic, environmental and ethical impact of the new technologies. This makes it not only suitable as supplementary material for students but also the perfect companion for policy makers and funding agencies, if they are to make informed decisions about synthetic biology. Largely coordinated by Markus Schmidt, a policy adviser, and the only European to testify in front of the bioethics commission of the Obama administration.

Author Biography

Markus Schmidt has an interdisciplinary background with an education in electronic and biomedical engineering, biology (MSc) and risk research (PhD). His research interests include risk assessment, the science-society interface, and technology assessment (TA) of novel bio-, nano- and converging technologies. Since 2005 he pioneered synthetic biology safety and ELSI (ethical, legal and social issues) research in Europe. See: www.markusschmidt.eu for details.

Table of Contents

List of Contributorsp. xi
Short CVs of Contributorsp. xiii
Prefacep. xvii
Acknowledgmentsp. xix
Executive Summaryp. xxi
Biofuelsp. xxi
Bioremediationp. xxii
Biomaterialsp. xxiv
Novel Developments in Synthetic Biologyp. xxv
Introductionp. 7
What Are Synthetic Biology Applications?p. 1
Which Synthetic Biology Applications Did We Consider?p. 2
Selecting and Assessing Synthetic Biology Applicationsp. 3
The Regulatory Context for Synthetic Biologyp. 4
Referencesp. 6
Biofuelsp. 7
Biofuels in Generalp. 7
Introductionp. 7
Economic Potentialp. 8
Environmental Impactp. 13
Land Requirements for Projected Biofuel Usep. 14
Other Environmental Concernsp. 16
Impact of Legislative Decicionsp. 16
Foreseeable Social and Ethical Aspectsp. 17
How Could the New SB Application Impact Society at Large?p. 18
Ethanolp. 19
Introductionp. 19
Economic Potentialp. 20
Environmental Impactp. 21
Foreseeable Social and Ethical Aspectsp. 24
Could the Application Change Social Interactions?p. 26
Producing Countries, Rich Countries?p. 26
Non-ethanol Fuelsp. 27
Introductionp. 27
Economic Potentialp. 31
Environmental Impactp. 32
Foreseeable Social and Ethical Aspectsp. 33
Impact on Social Interactionp. 34
Algae-based Fuelsp. 35
Introductionp. 35
Economic Potentialp. 37
Environmental Impactp. 41
Foreseeable Social and Ethical Aspectsp. 42
Could the Application Change Social Interactions?p. 42
Hydrogen Productionp. 43
Introductionp. 43
Economic Potentialp. 46
Cost Comparison with Gasoline for Transport Fuelsp. 46
Environmental Impactp. 49
Environmental Concernsp. 51
Foreseeable Social and Ethical Aspectsp. 51
Could the Application Change Social Interactions? If Yes, in Which Way?p. 52
Microbial Fuel Cells and Bio-photovoltaicsp. 52
Introductionp. 52
Economic Potentialp. 56
Environmental Impactp. 56
Foreseeable Social and Ethical Aspectsp. 59
Recommendations for Biofaelsp. 59
Referencesp. 61
Bioremediationp. 67
Bioremediation in Generalp. 67
Introductionp. 67
Economic Potentialp. 68
Environmental Impactp. 69
Foreseeable Social and Ethical Aspectsp. 70
Detection of Environmental Pollutants (Biosensors)p. 70
Introductionp. 70
Economic Potentialp. 73
Environmental Impactp. 74
Foreseeable Social and Ethical Aspectsp. 76
Water Treatmentp. 77
Introductionp. 77
Economic Potentialp. 78
Environmental Impactp. 78
Foreseeable Social and Ethical Aspectsp. 79
Water Desalination with Biomembranesp. 79
Introductionp. 79
Economic Potentialp. 80
Environmental Impactp. 81
Foreseeable Social and Ethical Aspectsp. 81
Soil and Groundwater Decontaminationp. 82
Introductionp. 82
Economic Potentialp. 83
Environmental Impactp. 84
Foreseeable Social and Ethical Aspectsp. 85
Solid Waste Treatmentp. 85
Introductionp. 85
Economic Potentialp. 87
Environmental Impactp. 87
Foreseeable Social and Ethical Aspectsp. 87
CO2 Recapturingp. 89
Introductionp. 89
Economic Potentialp. 92
How Is Carbon Traded?p. 93
Environmental Impactp. 95
A Foreseeable Social and Ethical Aspectsp. 96
Recommendations for Bioremediationp. 98
Referencesp. 99
Further Readingp. 101
Biomaterialsp. 103
Biomaterials in Generalp. 103
Introductionp. 103
Economic Potentialp. 104
Environmental Impactp. 106
Foreseeable Social and Ethical Aspectsp. 107
Biopolymers/Plasticsp. 108
Introductionp. 108
Economic Potentialp. 111
Environmental Impactp. 113
Foreseeable Social and Ethical Aspectsp. 115
Bulk Chemical Productionp. 117
Introductionp. 117
Economic Potentialp. 120
Environmental Impactp. 123
Foreseeable Social and Ethical Aspectsp. 124
Fine Chemical Productionp. 126
Introductionp. 126
Vitamins and Pharmaceuticalsp. 128
Economic Potentialp. 129
Environmental Impactp. 131
Foreseeable Social and Ethical Aspectsp. 133
Cellulosomesp. 134
Introductionp. 134
Economic Potentialp. 136
Environmental Impactp. 137
Foreseeable Social and Ethical Aspectsp. 138
Recommendations for Biomaterialsp. 139
Referencesp. 140
Further Readingp. 143
Other Developments in Synthetic Biologyp. 145
Protocellsp. 145
Introductionp. 145
Economic Potentialp. 147
Environmental Impactp. 147
Foreseeable Social and Ethical Aspectsp. 149
Xenobiologyp. 150
Introductionp. 150
Economic Potentialp. 152
Environmental Impactp. 152
Foreseeable Social and Ethical Aspectp. 154
Recommendations for Protocells and Xenobiologyp. 154
Referencesp. 155
Further Readingp. 156
Regulatory Frameworks for Synthetic Biologyp. 157
United States of Americap. 157
Introductionp. 157
United States Federal Regulations and Guidelinesp. 158
National Institutes of Health: Guidelines for Research Involving Recombinant DNA Moleculesp. 158
Environmental Protection Agency, US Department of Agriculture and Food and Drug Administrationp. 164
USDA Animal and Plant Heath Inspection Servicep. 167
Food and Drug Administrationp. 169
Department of Commerce Regulationsp. 170
Select Agent Rulesp. 172
Screening Guidance for Providers of Synthetic Double-Stranded DNAp. 175
International Conventions and Agreementsp. 176
The Convention on Biological Diversityp. 176
The Cartagena Protocol on Biosafery and the Nagoya-Kuala Lumpar Supplementary Protocol on Liabilityp. 177
The Biological Weapons Conventionp. 178
The Australia Group Guidelinesp. 179
Conclusions: Current Coverage and Future Considerationsp. 181
Current Coveragep. 181
Future Prospectsp. 183
Europep. 185
Introductionp. 185
Synthetic Biology as a Novel Science and Engineering Fieldp. 186
Synthetic Biology versus Genetic Engineeringp. 189
Existing Regulationsp. 190
European Unionp. 190
Examples of National Regulationsp. 195
Austriap. 196
Germanyp. 198
United Kingdomp. 201
Switzerlandp. 203
Options for Adapting and Improving Regulationsp. 205
Outlookp. 209
Chinap. 210
Introductionp. 210
General Provisionsp. 211
Biosecurity and Dual Usep. 217
Options for Adapting and Improving Regulationsp. 218
Outlookp. 219
Referencesp. 220
Further Readingp. 226
List of Biofuel Companiesp. 227
List of Bioremediation Companiesp. 229
Indexp. 237
Table of Contents provided by Ingram. All Rights Reserved.

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