Toxocara : The Enigmatic Parasite

by C. V. Holland; H. V. Smith

• ISBN13: 9781845930264
• ISBN10: 1845930266
• Format: Hardcover
• Copyright: 2006-04-20
• Publisher: Cab Intl

Summary

Toxocara is a parasitic helminth worm which continues to stimulate both public concern and scientific interest. Toxocara canis and T.cati, the most studied species, are gastrointestinal parasites of dogs and cats and their eggs can contaminate the environment, thus exposing humans and other mammals and birds to infection. Many questions remain unanswered about the host-parasite relationship, its epidemiology and public health significance. Veterinarians and clinicians are interested in its importance as a zoonosis. The parasite's capacity to cause ocular disease is of concern to ophthalmologists, while its propensity to stimulate allergic manifestations is of interest to allergologists, dermatologists and respiratory medicine specialists. Furthermore Toxocara provides a unique model system to explore questions in parasite biology.This book provides a comprehensive review of Toxocara and the disease it causes known as toxocariasis.

Table of Contents

List of Contributors	vii
Introduction	ix
SECTION 1: BIOLOGY OF TOXOGARA	1	(86)
Molecular Biology
Molecular Biology and Immunology of Toxocara canis	3	(15)
Rick M. Maizels
Irma Schabussova
Deborah M. Callister
Gavin Nicoll
Molecular Genetic Characterization of Members of the Genus Toxocara - Taxonomic, Population Genetic and Epidemiological Considerations	18	(14)
Robin B. Gasser
Xing-Quan Zhu
Min Hu
Dennis E. Jacobs
Neil B. Chilton
The Larval Surface	32	(10)
Malcolm W. Kennedy
Toxocara as a model system
Toxocara and Asthma	42	(16)
Elena Pinelli
Jan Dormans
Irma van Die
The Significance of Cerebral Toxocariasis	58	(16)
Celia V. Holland
Clare Hamilton
Animal models for toxocariasis
Critical Assessment of Existing and Novel Model Systems of Toxocariasis	74	(13)
Nobuaki Akao
SECTION 2: CLINICAL ASPECTS AND PUBLIC HEALTH	87	(150)
Human disease
Diagnostic Limitations and Future Trends in the Serodiagnosis of Human Toxocariasis	89	(24)
Huw Smith
Rahmah Noordin
Management and Treatment Options for Human Toxocariasis	113	(14)
Jean-Francois Magnaval
Lawrence T. Glickman
Ocular Toxocariasis	127	(18)
Mervyn R.H. Taylor
Toxocariasis and the Skin	145	(13)
Renaud Piarroux
Beatrice Gavignet
Stephanie Hierso
Philippe Humbert
Immunology of toxocariasis
Inflammatory and Immunological Responses to Toxocara canis	158	(16)
Stephen G. Kayes
Novel Approaches to Immunoprophylaxis for Toxocariasis	174	(21)
Gabriela Hrckova
Epidemiology of toxocariasis
Epidemiological Surveillance of Toxocara and Toxocariasis	195	(16)
John W. Lewis
Exposure and Environmental Contamination	211	(17)
Hanna Mizgajska-Wiktor
Shoji Uga
Baylisascariasis: an Emerging and Potentially Fatal Form of Larval Migrans	228	(9)
Corey S. Watts
Jennifer L. Liang
Peter M. Schantz
SECTION 3: TOXOCARA IN THE VETERINARY CONTEXT	237	(42)
Current and Future Options for the Prevention and Treatment of Canids	239	(14)
Christian Epe
Toxocariasis: the Veterinarian's Role in Prevention of Zoonotic Transmission	253	(7)
Peter M. Schantz
Toxocara vitulorum in Livestock	260	(19)
Wilma A. Starke-Buzetti
SECTION 4: ECONOMIC IMPACT OF THE DISEASE	279	(15)
Economic Impact of Toxocara spp	281	(13)
Paul R. Torgerson
Christine M. Budke
Index	294