When Experiments Travel

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  • Edition: 1st
  • Format: Paperback
  • Copyright: 2009-04-27
  • Publisher: Princeton Univ Pr

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The phenomenal growth of global pharmaceutical sales and the quest for innovation are driving an unprecedented search for human test subjects, particularly in middle- and low-income countries. Our hope for medical progress increasingly depends on the willingness of the world's poor to participate in clinical drug trials. While these experiments often provide those in need with vital and previously unattainable medical resources, the outsourcing and offshoring of trials also create new problems. In this groundbreaking book, anthropologist Adriana Petryna takes us deep into the clinical trials industry as it brings together players separated by vast economic and cultural differences. Moving between corporate and scientific offices in the United States and research and public health sites in Poland and Brazil,When Experiments Traveldocuments the complex ways that commercial medical science, with all its benefits and risks, is being integrated into local health systems and emerging drug markets.Providing a unique perspective on globalized clinical trials,When Experiments Travelraises central questions: Are such trials exploitative or are they social goods? How are experiments controlled and how is drug safety ensured? And do these experiments help or harm public health in the countries where they are conducted? Empirically rich and theoretically innovative, the book shows that neither the language of coercion nor that of rational choice fully captures the range of situations and value systems at work in medical experiments today.When Experiments Travelchallenges conventional understandings of the ethics and politics of transnational science and changes the way we think about global medicine and the new infrastructures of our lives.

Author Biography

Adriana Petryna is associate professor of anthropology at the University of Pennsylvania. She is the author of the award-winning Life Exposed: Biological Citizens after Chernobyl (Princeton) and the coeditor of Global Pharmaceuticals: Ethics, Markets, Practices.

Table of Contents

Abbreviationsp. ix
Introduction: Experimental Fieldsp. 1
The Search for Human Subjectsp. 1
Anthropology and the Global Clinical Trialp. 5
Ethical Variabilityp. 10
Why Are Clinical Trials Globalizing?p. 10
Treatment Saturationp. 19
Experimentalityp. 26
Ethics as "Workable Document"p. 33
Floater Sites and Hidden Harmsp. 41
The Aftermath of Clinical Trialsp. 44
Arts of Drug Developmentp. 47
Study Millsp. 47
Drug-Development Servicesp. 53
From Vulnerable to Professional Subjectsp. 61
The Pharmaceutical Boom and Everyday Researchp. 68
Engineering Out Harmp. 77
The Scientific Plateau and the New Safety Paradigmp. 85
The Global Clinical Trialp. 89
How Many Clinical Trials Are Being Carried Out Worldwide?p. 89
The Polish Market and the "Nonexistent" Patientp. 98
Clinical Research Frontiersp. 106
Collaborations in Global Sciencep. 109
Akademia Klinicznap. 116
The Work of Slackp. 119
Patient-Consumersp. 124
"Our society was not competitive"p. 127
Pivotal Countriesp. 130
Insurance and Legal Protectionp. 132
Pharmaceuticals and the Right to Healthp. 139
Reclaiming Patients and the Evidence Base of Drugsp. 139
"Pharmaceuticals are the new gold"p. 142
Health Technology Assessment in Brazilp. 146
The Judicialization of Healthp. 150
Alternative Treatment Guidelinesp. 153
The Clinical Research Unitp. 156
When a Country Is a Pharmacyp. 160
A Public Health Experimentp. 165
What Happens When Clinical Trials Endp. 167
The Values Patients Bringp. 173
Information Asymmetry and Agencyp. 179
Conclusion: The Future of Global Medicinep. 186
Scientific Evidence and Valuep. 186
Drugs as Public Goodsp. 190
Global Health Marketsp. 192
Innovationp. 195
Acknowledgmentsp. 201
Notesp. 205
Referencesp. 225
Indexp. 249
Table of Contents provided by Ingram. All Rights Reserved.

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