9780120103416

Advances in Clinical Chemistry

by
  • ISBN13:

    9780120103416

  • ISBN10:

    0120103419

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2006-03-31
  • Publisher: Elsevier Science
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Summary

Volume forty-two in the internationally acclaimed Advances in Clinical Chemistry series, contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics ranging from basic biochemical exploration to cutting edge microarray technology. In keeping with the tradition of the series, this volume emphasizes novel laboratory advances with application not only to both clinical laboratory diagnostics, but as well as practical basic science studies. This volume of Advances in Clinical Chemistry is an indispensable resource and practical guide for twenty-first century practitioners of clinical chemistry, molecular diagnostics, pathology, and clinical laboratory sciences in general.

Table of Contents

Contributors ix
Preface xiii
Is Taurine a Biomarker?
Georgia Schuller-Levis
Eunkyue Park
Taurine
1(12)
Taurine as a Biomarker
13(3)
Conclusions
16(7)
References
17(6)
Application of Nanoscale Bioassemblies to Clinical Laboratory Diagnostics
Jarrod Clark
Steven S. Smith
Introduction
23(2)
Protein Scaffolds
25(3)
DNA Scaffolds
28(8)
Organic Polymer Scaffolds
36(2)
Inorganic Scaffolds
38(3)
Discussion
41(1)
Conclusions
42(8)
References
42(8)
Cardiac Troponins: Clinical and Analytical Aspects
Ravinder Sodi
Abstract
50(1)
Introduction
50(1)
Structure and Biochemistry of Troponins
51(13)
Clinical Significance of Measured Cardiac Troponins
64(12)
Measurement of Cardiac Troponins
76(17)
Factors Affecting the Measurement of Cardiac Troponins
93(13)
Conclusions and Future Directions
106(17)
References
107(16)
Leptin Physiology and Pathophysiology in the Elderly
Elena Zoico
Mauro Zamboni
Vincenzo Di Francesco
Gloria Mazzali
Francesco Fantin
Ottavio Bosello
Abstract
123(1)
Introduction
124(1)
Background
125(1)
Regulation of Leptin Levels in the Elderly
126(14)
Clinical Implications of Leptin Physiology in the Elderly
140(1)
Leptin and the Anorexia of the Elderly
141(1)
Leptin and Glucose Metabolism
142(2)
Leptin, Leptin Resistance, and the Metabolic Syndrome
144(2)
Leptin and Bone Metabolism
146(11)
Conclusions
157(11)
References
158(10)
Biochemical Pathways of Wound Healing: Implications for Development of Disease-Specific Diagnostics
Nathan B. Menke
Robert F. Diegelmann
Abstract
168(1)
Introduction
168(1)
Acute Wound Healing
168(11)
Chronic Wounds: Overview
179(1)
Pressure Ulcers
179(2)
Diabetic Ulcers
181(1)
Venous Stasis Ulcers
182(1)
Fibrosis
182(1)
Modeling
183(2)
Summary
185(4)
References
186(3)
Clinical Laboratory Tools to Diagnose Inflammation
Undurti N. Das
Abstract
189(1)
Introduction
190(10)
Mediators of Inflammation
200(14)
Clinical Laboratory Tools to Diagnose Inflammation
214(5)
High Sensitive-CRP and Other Proinflammatory Indices as Markers of Cardiovascular Diseases: But, Why, and How?
219(3)
Conclusions
222(10)
References
223(9)
Advances in Prostate-Specific Antigen Testing
Ping Wu
Hannu Koistinen
Patrik Finne
Wan-Ming Zhang
Lei Zhu
Jari Leinonen
Ulf-Hakan Stenman
Abstract
232(1)
Introduction
232(1)
Prostate-Specific Antigen
233(4)
Measurement of PSA in Circulation
237(5)
New Approaches for Detection of PSA
242(4)
Detection of Circulating Prostate Cancer Cells by Measurement of PSA mRNA
246(1)
Enhancing Utility of PSA by Multivariate Methods
246(4)
Conclusions
250(13)
References
251(12)
Advances in Prion Disease Surveillance
Kristen Hatcher
Carrie Harris
Pierluigi Gambetti
Shu G. Chen
Abstract
263(1)
Introduction
264(2)
Prion Diagnostics
266(12)
Human Prion Disease Surveillance
278(10)
Conclusions
288(5)
References
289(4)
Index 293

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