9780120398546

Advances in Virus Research

by
  • ISBN13:

    9780120398546

  • ISBN10:

    0120398540

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 1999-10-01
  • Publisher: ACADEMIC PRESS INC

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Supplemental Materials

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Summary

Published since 1953, Advances in Virus Research covers a diverse range of in-depth reviews providing a valuable overview of the current field of virology.In 2004, the Institute for Scientific Information released figures showing that the series has an Impact Factor of 2.576, with a half-life of 7.1 years, placing it 11th in the highly competitive category of Virology.

Table of Contents

The Life and Times of Adenoviruses
Harold S. Ginsberg
Text
1(11)
References
12(3)
Role of Outer Capsid Proteins in Transmission of Phytoreovirus by Insect Vectors
Toshihiro Omura
Jin Yan
Introduction
15(2)
Localization of Structural Proteins in Particles of Phytoreovirus
17(1)
Role of P2 Protein in Viral Infection of Insect Vector Cells
18(5)
Correlation between Infectivity and Presence of P2 Protein in RGDV
23(4)
P2 Protein Allowing RDV to Adsorb to Insect Vector Cells
27(4)
Absence of P2 Protein Expression in Transmission-Defective Isolate of RDV
31(6)
P8 Outer Capsid Protein of RDV Involved in Viral Infection of Insect Vector Cells
37(1)
Concluding Remarks
38(7)
References
39(6)
Replication of Human Hepatitis Delta Virus: Influence of Studies on Subviral Plant Pathogens
John M. Taylor
Introduction and Scope
45(1)
Early History
46(1)
Transmission, Epidemiology, and Pathogenesis
47(1)
Initial Application of Molecular Virology
48(1)
Initial Similarities to Plant Agents
49(1)
Subsequent Molecular Virology
50(4)
Subsequent Similarities to Plant Agents
54(3)
Conclusions and Outlook
57(4)
References
58(3)
Regulation of Human Cytomegalovirus Gene Expression
Elizabeth A. Fortunato
Deborah H. Spector
Introduction
61(2)
Viral Entry
63(1)
Immediate Early Events Mediated by Initial Virus--Host Interaction
64(5)
Utilization of Preexisting Nuclear Architecture by HCMV
69(1)
Influence of Host Cell Cycle Phase on IE Gene Expression
69(1)
Major Immediate Early Gene Expression IE1/IE2 (UL123/122)
70(21)
Other IE Gene Products
91(5)
Activation of Early Genes
96(12)
Regulation of True Late Genes
108(3)
Conclusions
111(18)
References
112(17)
DNA Vaccines: A Review
P. Jeff Lewis
Lorne A. Babiuk
DNA-Based Vaccines
129(3)
Serum Kinetics and Uptake Mechanisms
132(2)
Mechanism of Antigen Presentation
134(5)
Adjuvancy Effects of Bacterially Derived DNA
139(2)
Immune Response to DNA-Based Vaccines
141(9)
Mucosal and Epidermal Delivery
150(4)
Transdermal Delivery
154(1)
Cytokine Modulation of Immunity to DNA-Based Vaccines
155(9)
Safety
164(4)
Future Directions
168(7)
Summary
175(14)
References
177(12)
Epidemiological Risks from Mixed Virus Infections and Transgenic Plants Expressing Viral Genes
John Hammond
Herve Lecoq
Benjamin Raccah
Introduction
189(3)
Mixed Infections
192(39)
Transgenic Plants
231(30)
Analysis of Risk and Proactive Risk Reduction
261(22)
Concluding Remarks
283(36)
References
289(28)
Special Section: RESPIRATORY VIRUSES
Joseph L. Waner
Introduction
Joseph L. Waner
Text
317(2)
Replication of Orthomyxoviruses
Agustin Portela
Thomas Zurcher
Amelia Nieto
Juan Ortin
Introduction
319(1)
Ion Channel Protein
320(4)
Return Ticket for RNP: Nucleocytoplasmic Transport of Influenza Genome
324(4)
Transcription and Replication: Structure and Regulation of RNP Complex
328(8)
Virus Assembly
336(3)
Future Prospects
339(10)
References
340(9)
Influenza Vaccines: Present and Future
Kanta Subbarao
Introduction
349(2)
Trivalent Inactivated Vaccine
351(4)
Recombinant and Subunit Vaccines
355(1)
Live Attenuated Influenza Vaccines
356(6)
Future Developments in Vaccines
362(2)
Summary
364(11)
References
365(10)
Influenza Neuraminidase as Target for Antivirals
Gillian M. Air
Anita A. Ghate
Stephen J. Stray
Introduction
375(1)
Antiviral Agents
376(9)
Structure-Based Drug Design
385(6)
Concluding Remarks
391(12)
References
397(6)
Replication of Paramyxoviruses
Joseph Curran
Daniel Kolakofsky
Virion Structure and Genome Organization
403(2)
Key Players
405(8)
Supporting Cast
413(3)
Genome Expression
416(1)
Summary
417(6)
References
418(5)
Rational Design of Live-Attenuated Recombinant Vaccine Virus for Human Respiratory Syncytial Virus by Reverse Genetics
Peter L. Collins
Stephen S. Whitehead
Alexander Bukreyev
Rachel Fearns
Michael N. Teng
Katalin Juhasz
Robert M. Chanock
Brian R. Murphy
Introduction
423(1)
Respiratory Syncytial Virus
424(6)
RSV Disease
430(1)
Immunity of RSV
431(1)
Obstacles to Development of RSV Vaccine
432(1)
RSV Reverse Genetics: Antigenic Subgroup A
433(4)
Expression of Foreign Genes in Recombinant RSV
437(1)
Gene Knockouts
438(1)
Biologically Derived RSV Subgroup A Candidate Vaccine Viruses
439(4)
Rational Design of Recombinant RSV Subgroup A Vaccine
443(1)
Advantages of Recombinant DNA Method
444(2)
Current Directions
446(1)
Summary
446(7)
References
447(6)
Clinical Virology of Rhinoviruses
J. Owen Hendley
Introduction
453(1)
Attributes of Virus and Epidemiology of Disease
454(2)
Detection of Rhinovirus
456(4)
Pathogenesis of Symptoms
460(4)
Summary
464(3)
References
465(2)
Index 467

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