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Acknowledgments | p. 9 |
Preface | p. 11 |
The Inspiration | p. 15 |
The Largest Kindred in the World with Familial Alzheimer's Disease | p. 15 |
One Family's Story of Familial Alzheimer's: The Noonans | p. 28 |
Alzheimer's Disease on the World Stage | p. 39 |
Why We Need Neighborhood Cognitive Shops | p. 59 |
Nowhere to Turn | p. 59 |
The Neighborhood Cognitive Shop | p. 65 |
Community Acceptance of Cognitive Centers and Physician Referral Patterns | p. 70 |
Achieving Lifelong Brain Health | p. 72 |
Finding Support in the Community | p. 73 |
Understanding The Basics: Where We are, How We Got Here | p. 79 |
The Academy Delivers the Fundamental Biology | p. 80 |
Big Pharma Sets the Agenda | p. 82 |
On to the Food and Drug Administration | p. 84 |
Getting the Basics Right: The First Step toward Drug Discovery | p. 86 |
Alzheimer's Disease Research Goes Molecular | p. 90 |
The Plaque and Tangle Cartels: How Research Was Stymied | p. 95 |
Pure Alzheimer's Disease Is Not the Most Common Form of Dementia | p. 97 |
New Directions | p. 98 |
The Medical Model Hits The Shoals | p. 107 |
What Is the Medical Model? | p. 107 |
Medicine and Social Change | p. 114 |
Reappraising the Problem of Cognition in Elders | p. 120 |
The Medical Model Will Not Work in the Coming Genetic Revolution | p. 122 |
At the Boundaries of the Medical Model | p. 125 |
Application of the Medical Model to Conditions That Affect the Mind | p. 127 |
Application of the Medical Model to Conditions That Affect the Brain | p. 128 |
The Alzheimer Burden and The Coming Epidemic | p. 137 |
Alzheimer Disease by the Numbers | p. 138 |
Institutionalization | p. 140 |
The Alzheimer Epidemic Is Coming at a Time When the Healthcare System is in Peril | p. 150 |
A Dance With Two Partners: The Marketplace and The Regulators | p. 161 |
The System Stymies Physician Creativity | p. 161 |
Regulation: Can't Live with It and Can't Live without It | p. 163 |
Paying High Prices for Drugs with Modest Effects | p. 166 |
Biological Research Will Create a Medical Treatment Tier Available to Only a Select Few: High Medical Costs are about to Soar | p. 170 |
The Off-Label Quagmire and the Compassionate-Use Quicksand | p. 173 |
Employer Coverage Will Require Lifestyle Changes to Reduce Risk | p. 176 |
Cognitive Impairment and Decision Making | p. 179 |
Why Do People Who are Strongly Opposed to Receiving Total Care Often End Up Receiving Total Care If They Become Demented? | p. 179 |
Apathy Replaces Despondency | p. 183 |
Predicting Alzheimer's Disease | p. 184 |
Physician-Assisted Suicide Rules are Not Applicable to Alzheimer's Disease | p. 187 |
End-of-Life Issues for Alzheimer's Patients: The Need for a New Ethical Landscape | p. 189 |
Facing the Prospect of Alzheimer's Disease while Still Cognitively Intact | p. 194 |
Alzheimer's In The Information Age | p. 199 |
Thirst for Information in a Sea of Information | p. 199 |
From Information to Knowledge: Social Networks and the Medical Wiki | p. 203 |
The Privacy Issue ... or Not? | p. 213 |
Doctors Will No Longer Diagnose | p. 214 |
Your Doc Goes Virtual | p. 216 |
Telling Our Story in an E-World Setting | p. 224 |
The Challenge of Optimizing Lifestyles | p. 227 |
Exercise | p. 228 |
Diet | p. 234 |
Cognitive Challenges | p. 237 |
Friends | p. 243 |
Chronic Stress-An Inner Time Bomb | p. 246 |
The Happiness Solution | p. 251 |
Social Networks Drive Adherence | p. 255 |
Conclusions | p. 263 |
Index | p. 271 |
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The Used, Rental and eBook copies of this book are not guaranteed to include any supplemental materials. Typically, only the book itself is included. This is true even if the title states it includes any access cards, study guides, lab manuals, CDs, etc.