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List of contributors | p. ix |
Preface | p. xi |
Introduction | p. 1 |
Ecological function of secondary metabolites | p. 1 |
Presence of defence and signal compounds at the right time and place | p. 4 |
Molecular modes of action of SM | p. 8 |
Biotechnology and utilization of SM | p. 13 |
Conclusions | p. 16 |
Molecular Modes of Action of Defensive Secondary Metabolites | p. 21 |
Introduction | p. 21 |
Molecular modes of action - an overview | p. 22 |
Accumulation of defence and signal compounds in plants | p. 128 |
Animal responses: detoxification mechanisms and adaptations | p. 132 |
Concluding remarks | p. 137 |
Chemical Defence in Marine Ecosystems | p. 162 |
Introduction | p. 162 |
Marine natural products in allelopathic interactions | p. 165 |
Chemical defence against fouling | p. 168 |
Chemical defences of marine invertebrates and algae against consumers | p. 173 |
Favoured allocation of defensive metabolites in vulnerable and valuable parts of marine invertebrates and algae | p. 182 |
The flexible response: stress-induced accumulation of defence metabolites and activation of protoxins | p. 186 |
Endosymbionts as sources for allelochemicals found in marine invertebrates | p. 193 |
Conclusions and outlook | p. 201 |
Plant-Microbe Interactions and Secondary Metabolites with Antibacterial, Antifungal and Antiviral Properties | p. 214 |
Introduction | p. 215 |
Phytoalexins | p. 217 |
Antibacterial and antifungal agents of higher plants | p. 232 |
Secondary metabolities from higher plants with antiviral properties | p. 278 |
Conclusions | p. 317 |
New Medical Applications of Plant Secondary Metabolites | p. 348 |
Introduction | p. 349 |
Compounds with anticancer and chemopreventive activity | p. 349 |
Antiviral compounds | p. 359 |
Antimalarial drugs | p. 360 |
Anti-inflammatory drugs | p. 361 |
Antidepressant drugs | p. 363 |
Anti-ischaemic drugs | p. 364 |
Immunostimulatory drugs | p. 365 |
Conclusions | p. 366 |
Production of Natural Products by Plant Cell and Organ Cultures | p. 381 |
Introduction | p. 381 |
Production of natural products by cell and organ cultures | p. 383 |
Elicitation | p. 383 |
Increase/decrease of product yields by genetic manipulation | p. 384 |
Biosynthetic pathways delineation using RNA-interference | p. 385 |
Mass cultivation of plant cell cultures | p. 386 |
Production of recombinant proteins by plants and plant cell cultures | p. 388 |
Production of plant natural products in microbes | p. 389 |
Perspectives | p. 390 |
Index | p. 399 |
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The Used, Rental and eBook copies of this book are not guaranteed to include any supplemental materials. Typically, only the book itself is included. This is true even if the title states it includes any access cards, study guides, lab manuals, CDs, etc.