Annual Reports in Medicinal Chemistry

by Desai

• ISBN13: 9780123743442
• ISBN10: 0123743443
• Edition: 1st
• Format: Paperback
• Copyright: 2008-10-20
• Publisher: Elsevier Science

Summary

Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies. * covers findings related to cardiovascular, inflammation, and pulmonary diseases * examines issues in oncology, from mTor inhibitors to drug targets * incorporates up-to-date information on drug design and discovery, including delivery to market

Table of Contents

Central Nervous System Diseases ¿C ROBICHAUD

Recent Advances in Corticotropin Releasing Factor Receptor Antagonists

Recent Advances on the 5-HT5A, 5-HT6 and 5-HT7 Receptors

Recent Advances in Voltage Gated Sodium Channel Blockers: Therapeutic Potential as Drug Targets in the CNS

Medication Development for the Treatment of Substance Abuse

Cardiovascular and Metabolic Diseases - STAMFORD

GPR40 (FFAR1) Modulators

Rho-Kinase Inhibitors for Cardiovascular Disease

LXR Agonists for the Treatment of Atherosclerosis - Recent Highlights

Glucagon Receptor Antagonists for Type II Diabetes

Inflammation / Pulmonary / GI ¿C BARRISH

Advances Towards Dissociated Non-Steroidal Glucocorticoid Receptor Agonists

Advances in the Discovery of IkB Kinase Inhibitors

Protease Inhibitors for the Potential Treatment of Chronic Obstructive Pulmonary Disease and Asthma

Oncology - MYLES

mTor Inhibitors in Oncology

Oncology Drug Targets in the Sphingomyelin Signaling Path

Infectious Diseases - Primeau

Inhibitors of Respiratory Syncytial Virus

Recent Developments in  --Lactamases and Inhibitors

Recent Development in the Treatment of Clostridium Difficile Associated Disease (CDAD)

Recent Advances in the Discovery of Hybrid Antibacterial Agents

Topics in Biology - LOWE

Recent Renaissance of Prostaglandin Research

Human Exposure and Dose Projections

Modeling Networks of Glycolysis, Overall Energy Metabolism and Drug Metabolism under a Systems Biology Approach

Topics in Drug Design and Discovery ¿C DESAI

Contrasting the Gastrointestinal Tracts of Mammals: Factors that Influence Absorption

The Emerging Utility of Co-Crystals in Drug Discovery and Development

Pregnane X Receptor: Prediction and Attenuation of Human CYP3A4 Enzyme Induction and Drug-Drug Interactions

Formulation in Drug Discovery

To Market, To Market

To Market, To Market - 2007

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