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Foreword | p. v |
Preface | p. xi |
List of Contributors | p. xiii |
Screening, Bioinformatics, Chemoinformatics, and Drug Design | p. 1 |
Drug Discovery Approaches Toward Anti Parasitic Agents | p. 3 |
New Bioinformatic Strategies Against Apicomplexan Parasites | p. 21 |
Sorting Potential Therapeutic Targets in Apicompiexa | p. 35 |
Alternatives to Drug Development in the Apicompiexa | p. 53 |
Metabolic Pathways and Processes Addressed by Current Drug Discovery Approaches | p. 75 |
Energy Metabolism as an Antimalarial Drug Target | p. 77 |
Polyamines in Apicomplexan Parasites | p. 97 |
The Reducing Milieu of Parasitized Cells as a Target of Antimalarial Agents: Methylene Blue as an Ethical Drug | p. 225 |
Lipids as Drug Targets for Malaria Therapy | p. 137 |
Targeting Apicoplast Pathways in Plasmodium | p. 163 |
Lipoic Acid Acquisition and Glutathione Biosynthesis in Apicomplexan Parasites | p. 287 |
Antimalarial Drugs and Molecules Inhibiting Hemozoin Formation | p. 205 |
Exploiting the Vitamin Metabolism of Apicomplexa as Drug Targets | p. 235 |
Vitamin Biosynthetic Pathways, the PLP Synthase Complex, and the Potential for Targeting Protein-Protein Interaction | p. 251 |
Targeting Prokaryotic Enzymes in the Eukaryotic Pathogen Cryptosporidium | p. 271 |
Drug Targets in Apicomplexan Parasites | p. 287 |
Novel Apicomplexan Phosphatases and Immunophilins as Domain Specific Drug Targets | p. 289 |
Dehydrogenases and Enzymes of the Mitochondrial Electron Transport Chain as Anti-Apicomplexan Drug Targets | p. 307 |
Calcium Dependent Protein Kinases as Drug Targets in Apicomplexan Parasites | p. 319 |
Protein Acylation: New Potential Targets for Intervention Against the Apicomplexa | p. 335 |
Drugs and Drug Targets in Neospora caninum and Related Apicomplexans | p. 359 |
Compounds | p. 373 |
Subversive Substrates of Glutathione Reductases from Plasmodium falciparum-Infected Red Blood Cells as Antimalarial Agents | p. 375 |
Ferroquine: A Concealed Weapon | p. 397 |
Current Aspects of Endoperoxides in Antiparasitic Chemotherapy | p. 413 |
Plasmodium Hsp90 as an Antimalarial Target | p. 431 |
Drug Discovery Against Babesia and Toxoplasma | p. 453 |
Search for Drugs and Drug Targets against Babesia bovis, Babesia bigemina, Babesia caballi, and Babesia (Theileria) equi | p. 469 |
Orlistat: A Repositioning Opportunity as a Growth Inhibitor of Apicomplexan Parasites? | p. 482 |
Recent Drug Discovery Against Cryptosporidium | p. 493 |
Index | p. 523 |
Table of Contents provided by Ingram. All Rights Reserved. |
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The Used, Rental and eBook copies of this book are not guaranteed to include any supplemental materials. Typically, only the book itself is included. This is true even if the title states it includes any access cards, study guides, lab manuals, CDs, etc.