Ashgate Handbook of Endocrine Agents and Steroids

by Milne, G. W. A.

• ISBN13: 9780566083839
• ISBN10: 0566083833
• Edition: 1st
• Format: Hardcover
• Copyright: 2000-09-01
• Publisher: WILEY

Summary

Treatment of endocrine disorders is an important branch of medicine and many drugs have been developed for use in this area. Endocrine disorders and the drugs used to treat them are quite diverse, ranging from iodine-containing thyroxine analogs used to treat hypothyroidism, to steroid androgens, progestins and estrogens.This Handbook contains records for all the major drugs currently used in endocrinology. Monographs are provided for 818 endocrine agents and steroids. For each main entry, the following information is provided: the chemical name and a list of trade names and synonyms; the Chemical Abstracts Service (CAS) Registry Number; the European Inventory of Existing Commercial Chemical Substances (EINECS) Number, and the Merck Index (12th edition) Number. The physical properties of each compound are described and the known biological activity and indicated applications are presented. The structure of each compound is provided, together with a summary of the acute toxicity data associated with it, and the manufacturers and suppliers of the drug are also given. Indexes, including a master index of names and synonyms, are appended.

Author Biography

G W A Milne was a Senior Researcher at the National Institutes of Health in Bethesda, MD, USA for 35 years where he worked on the use of spectroscopy for structure determination of organic compounds, and on molecular modeling in the design of drugs for the treatment of cancer and AIDS. He has been active for many years in the fields of chemical information and chemical computation and is the Editor of the American Chemical Society’s Journal of Chemical Information and Computer Science; Gardner’s Chemical Synonyms and Trade Names, Eleventh Edition (Ashgate); and Drugs: Synonyms and Properties (Ashgate).

Table of Contents

Preface	vii
Acknowledgements	ix
How to Use This Book	xi
Glossary of Units	xv
Abbreviations and Symbols	xvii
PART I MAIN ENTRIES	1	(146)
Pituitary/Hypothalamic Agents	3	(17)
Adrenocorticotropic Hormones	3	(1)
Antidiuretics	3	(1)
Antigonadotropins	4	(1)
Gonad Stimulating Principles	5	(3)
Growth Hormone-Releasing Factors	8	(1)
Growth Stimulants	8	(3)
Lactation Stimulating Hormones	11	(1)
LH-RH Agonists	11	(2)
Oxytocics	13	(4)
Prolactin Inhibitors	17	(2)
Somatostatins	19	(1)
Thyrotropic Hormones	19	(1)
Adrenocortical Agents	20	(3)
Adrenocortical Suppressants	20	(1)
Aldosterone Antagonists	21	(2)
Androgens and Anabolic Steroids	23	(19)
Anabolic Steroids	23	(8)
Androgens	31	(8)
Antiprostatic Hypertrophy Agents	39	(3)
Calcium Metabolizing Agents	42	(8)
Antiosteoporotics	42	(4)
Antipagetics	46	(2)
Bone Resorption Inhibitors	48	(2)
Estrogens and Progestins	50	(30)
Antiestrogens	50	(5)
Contraceptives	55	(3)
Estrogens	58	(9)
Progestogens	67	(13)
Glucose Regulating Agents	80	(18)
Aldose Reductase Inhibitors	80	(1)
Antidiabetics	81	(15)
CCK Antagonists	96	(1)
Insulin Sensitizers	97	(1)
Thyroids and Antithyroids	98	(6)
Antihyperthyroids	98	(2)
Antihypothyroids	100	(2)
Thyroid Hormones	102	(2)
Steroids, General	104	(43)
Mineralocorticoids and Glucocorticoids	104	(26)
Steroidal Anti-inflammatories	130	(17)
PART II INDEXES	147	(72)
CAS Registry Number Index	149	(10)
EINECS Number Index	159	(6)
Name and Synonym Index	165	(54)
PART III MANUFACTURERS AND SUPPLIERS DIRECTORY	219