Atlas of Renal Pathology

by Kern, William F., M.D.; Silva, Fred G.

• ISBN13: 9780721670676
• ISBN10: 0721670679
• Format: Hardcover
• Copyright: 1999-02-01
• Publisher: Elsevier Science Health Science div

Summary

This atlas/text is based on a broad overview of medical and surgical diseases of the kidney and organized upon a consistent and well-utilized approach to the study of renal diseases. Covers both neoplastic and non-neoplastic conditions, and also includes a section devoted to renal tumors. Features over 350 renal pathology slides, including light microscopy, immunofluorescence and electron microscopy, from the standout collections of two respected experts!

Table of Contents

CHAPTER 1 The Normal Kidney	1	(6)
Gross Anatomy	1	(1)
Microscopic Anatomy	1	(6)
CHAPTER 2 Classification of Renal Diseases and Mechanisms of Renal Injury	7	(5)
Classification of Renal Diseases	7	(2)
Mechanisms of Renal Injury	9	(3)
CHAPTER 3 Tissue Sampling, Preparation, and Interpretation	12	(2)
Introduction	12	(1)
Light Microscopy	12	(1)
Immunofluorescence	12	(1)
Electron Microscopy	13	(1)
Generalizations About Glomerular Diseases	13	(1)
CHAPTER 4 The True (Hypercellular of "Proliferative") Glomerulonephritides: Diseases Associated With the Nephritic Syndrome	14	(24)
Introduction	14	(1)
Mesangial Proliferative Glomerulonephritis	15	(1)
Acute Diffuse Intracapillary Proliferative Glomerulonephritis (Usually Postinfectious)	16	(5)
Membranoproliferative (Mesangiocapillary) Glomerulonephritis	21	(7)
Diffuse Extracapillary Proliferative (Crescentic) Glomerulonephritis	28	(6)
Focal Glomerulonephritis	34	(4)
CHAPTER 5 The Nonglomerulonephritic Glomerulonephropathies: Diseases Manifested as Severe Proteinuria or Idiopathic Nephrotic Syndrome	38	(19)
Introduction	38	(1)
Minimal Change Nephrotic Syndrome	39	(6)
Focal Segmental Glomerulosclerosis	45	(5)
Membranous Glomerulonephropathy	50	(7)
CHAPTER 6 Conditions With Isolated or Predominant Hematuria: IgA Nephropathy, Henoch-Schonlein Purpura, and Loin Pain -- Hematuria Syndrome	57	(11)
Conditions With Isolated Hematuria	57	(1)
IgA Nephropathy	58	(6)
Henoch-Schonlein Purpura	64	(2)
Loin Pain--Hematuria Syndrome	66	(2)
CHAPTER 7 Diseases Associated With Acellular Closure of Glomerular Capillaries: The Thrombotic Microangiopathies	68	(10)
Hemolytic-Uremic Syndrome and Thrombotic Thrombocytopenic Purpura	68	(9)
Preeclampsia and Eclampsia	77	(1)
CHAPTER 8 The Nephropathies of Systemic Lupus Erythematosus and Other Rheumatologic Disorders	78	(19)
Introduction	78	(1)
Systemic Lupus Erythematosus	78	(15)
Rheumatoid Arthritis	93	(1)
Mixed Connective Tissue Disease	93	(1)
Progressive Systemic Sclerosis (Systemic Scleroderma)	93	(2)
Sjogren's Syndrome	95	(2)
CHAPTER 9 The Kidney in Metabolic Disorders: Diabetes Mellitus, Hyperuricemia, Oxalosis, Nephrocalcinosis, and Nephrolithiasis	97	(16)
Diabetic Nephropathy	97	(10)
Urate Nephropathy	107	(1)
Oxalosis	108	(1)
Nephrocalcinosis	109	(2)
Nephrolithiasis	111	(2)
CHAPTER 10 The End-Stage Kidney	113	(5)
Introduction	113	(1)
Morphologic Changes	113	(1)
Gross Findings	113	(1)
Light Microscopy	114	(2)
Immunofluorescence Microscopy	116	(1)
Electron Microscopy	116	(1)
Changes in the Renal Medulla	117	(1)
Oxalate Deposits	117	(1)
Complications	117	(1)
CHAPTER 11 Disorders of the Glomerular Basement Membrane: Alport's Syndrome, Nail-Patella Syndrome, and Thin-Basement-Membrane Disease	118	(8)
Alport's Syndrome	118	(4)
Nail-Patella Syndrome	122	(2)
Thin-Basement-Membrane Nephropathy	124	(2)
CHAPTER 12 Disorders of the Tubules	126	(10)
Acute Tubular Necrosis: Ischemic Acute Tubular Nephropathy and Toxic Renal Injury	126	(4)
Other Tubular Abnormalities	130	(6)
CHAPTER 13 Disorders of the Interstitium: Interstitial Nephritis, Pyelonephritis, Papillary Necrosis, Analgesic Nephropathy, and Obstructive Nephropathy (Hydronephrosis)	136	(23)
Interstitial Nephritis	136	(6)
Pyelonephritis	142	(9)
Papillary Necrosis and Analgesic Nephropathy	151	(2)
Obstructive Nephropathy (Hydronephrosis)	153	(6)
CHAPTER 14 Vascular Diseases of the Kidney: Ischemic Renal Disease, Thromboembolism, Hypertension, Renal Cortical Necrosis, and Renal Vein Thrombosis	159	(13)
Introduction	159	(1)
Renal Artery Stenosis	159	(2)
Renal Infarction	161	(2)
Cholesterol Emboli	163	(2)
Hypertension and the Kidney	165	(3)
Renal Cortical Necrosis	168	(1)
Renal Vein Thrombosis	169	(3)
CHAPTER 15 Vasculitis and the Kidney: Polyarteritis Nodosa, Wegener's Granulomatosis, Churg-Strauss Syndrome, Mixed Cryoglobulinemia, and Other Forms of Vasculitis	172	(15)
Introduction	172	(1)
Polyarteritis (Periarteritis) Nodosa	172	(5)
Wegener's Granulomatosis	177	(3)
Churg-Strauss Syndrome (Allergic Granulomatosis)	180	(1)
Essential Mixed Cryoglobulinemia	181	(4)
The Kidney in Other Forms of Vasculitis	185	(2)
CHAPTER 16 HIV-Associated Nephropathy and Intravenous Drug Abuse	187	(7)
Introduction	187	(1)
HIV-Associated Nephropathy	187	(5)
Heroin-Associated Nephropathy	192	(2)
CHAPTER 17 Miscellaneous Conditions Affecting the Kidney: Liver Disease, Sickle Cell Nephropathy, Clq Nephropathy, Collagen Type III Glomerulopathy, and Fibronectin Glomerulopathy	194	(15)
Introduction	194	(1)
Liver Disease and the Kidney	194	(4)
Sickle Cell Anemia and the Kidney	198	(3)
Clq Nephropathy	201	(2)
Collagen Type III Glomerulopathy	203	(3)
Fibronectin Glomerulopathy	206	(3)
CHAPTER 18 Renal Effects of Extrarenal Neoplasms	209	(3)
Introduction	209	(1)
Renal Metastases From Extrarenal Neoplasms	209	(1)
Systemic and Metabolic Effects of Extrarenal Neoplasms	209	(1)
Renal Toxicities of Cancer Chemotherapy	210	(1)
Radiation Nephritis	210	(1)
Glomerular Effects of Extrarenal Neoplasms	210	(2)
CHAPTER 19 Plasma Cell Dyscrasias, Monoclonal Gammopathies, and the Fibrillary Glomerulopathies: Multiple Myeloma, Light Chain Deposition Disease, Amyloidosis, Fibrillary Glomerulonephritis, and Immunotactoid Glomerulopathy	212	(23)
Introduction	212	(1)
Multiple Myeloma and Renal Disease (Myeloma Cast Nephropathy)	213	(5)
Light Chain Deposition Disease	218	(3)
Waldenstrom's Macroglobulinemia	221	(1)
Amyloidosis	221	(7)
The Fibrillary Glomerulopathies: Fibrillary Glomerulonephritis and Immunotactoid Glomerulopathy	228	(7)
CHAPTER 20 Cystic Renal Diseases and Renal Dysplasia	235	(12)
Introduction	235	(1)
Autosomal Dominant Polycystic Kidney Disease	235	(3)
Autosomal Recessive Polycystic Kidney Disease	238	(2)
Nephronophthisis--Medullary Cystic Disease Complex	240	(1)
Medullary Sponge Kidney	241	(1)
Acquired Cystic Kidney Disease	241	(2)
Simple Renal Cysts	243	(1)
Renal Dysplasia	244	(3)
CHAPTER 21 Pathology of Renal Transplantation	247	(14)
Introduction	247	(1)
Hyperacute Rejection	247	(1)
Acute Interstitial (Cellular) Rejection	248	(3)
Acute Vascular (Humoral) Rejection	251	(2)
Chronic Rejection	253	(3)
Banff Classification of Renal Transplant Rejection	256	(1)
Cyclosporine and FK-506 Nephrotoxicity	256	(2)
Posttransplant Lymphoproliferative Disorders	258	(3)
CHAPTER 22 Pediatric Tumors and Tumor-Like Conditions of the Kidney	261	(14)
Introduction	261	(1)
Nephroblastoma (Wilms Tumor)	261	(5)
Nephrogenic Rests and Nephroblastomatosis	266	(1)
Cystic Nephroma (Multilocular Cyst) and Cystic Partially Differentiated Nephroblastoma	266	(2)
Mesoblastic Nephroma	268	(2)
Clear Cell Sarcoma of the Kidney	270	(1)
Rhabdoid Tumor	271	(1)
Metanephric Adenofibroma	272	(1)
Ossifying Renal Tumor of Infancy	273	(1)
Lymphangioma	273	(1)
Intrarenal Teratomas	273	(1)
Other Uncommon Pediatric Neoplasms	273	(2)
CHAPTER 23 Adult Renal Tumors and Tumor-Like Conditions	275	(34)
Introduction	275	(1)
Classification of Renal Epithelial Neoplasms	275	(1)
Renal Cell Carcinoma	275	(4)
Clear Cell (Nonpapillary) Renal Cell Carcinoma	279	(4)
Papillary (Chromophil) Renal Cell Carcinoma	283	(1)
Chromophobe Renal Cell Carcinoma	284	(2)
Collecting Duct Carcinoma	286	(2)
Sarcomatoid Renal Cell Carcinoma	288	(1)
Cystic Renal Cell Carcinoma	289	(1)
Renal Cell Carcinoma, Unclassified	289	(1)
Renal Epithelial Hyperplasia and Cortical Adenoma	290	(1)
Oncocytoma	291	(2)
Metanephric Adenoma	293	(1)
Miscellaneous Tumors With Epithelial or Renal Parenchymal Differentiation	294	(1)
Neuroendocrine Tumors	294	(1)
Primitive Neuroectodermal Tumor (PNET)	295	(1)
Juxtaglomerular Cell Tumor	296	(1)
Cystic Nephroma and Cystic Partially Differentiated Nephroblastoma	297	(1)
Nephroblastoma (Wilms Tumor)	297	(1)
Teratoma	297	(1)
Benign Renal Mesenchymal Neoplasms	298	(1)
Angiomyolipoma	298	(3)
Renomedullary Interstitial Cell Tumor	301	(1)
Adult Mesoblastic Nephroma	301	(1)
Other Benign Mesenchymal Neoplasms	302	(1)
Leiomyoma	302	(1)
Hemangioma	302	(1)
Lymphangioma	303	(1)
Lipoma	303	(1)
Solitary Fibrous Tumor	303	(1)
Malignant Mesenchymal Tumors	303	(1)
Leiomyosarcoma	303	(1)
Liposarcoma	304	(1)
Hemangiopericytoma	304	(1)
Fibrous and Malignant Fibrous Histiocytoma	304	(1)
Other Renal Sarcomas	304	(1)
Metastatic Neoplasms Involving the Kidney	304	(5)
CHAPTER 24 Tumors and Tumor-Like Conditions of the Renal Pelvis	309	(10)
Introduction	309	(1)
Malignant Epithelial Neoplasms	310	(1)
Transitional Cell Carcinoma	310	(4)
Squamous Cell Carcinoma	314	(1)
Adenocarcinoma	314	(1)
Small Cell Carcinoma	315	(1)
Benign Epithelial Neoplasms	315	(1)
Nonneoplastic Proliferative, Metaplastic, and Inflammatory Lesions	315	(2)
Mesenchymal Neoplasms	317	(2)
Index	319