Bacillus Subtilis and Its Closest Relatives

by Sonenshein, Abraham L.; Losick, Richard M.; Hoch, James A.; Losick, Richard

• ISBN13: 9781555812058
• ISBN10: 1555812058
• Format: Hardcover
• Copyright: 2001-10-01
• Publisher: Amer Society for Microbiology

Summary

Bacillus subtilis has become the principle paradigm for analysis of the physiology of gram-positive bacteria, bacterial differentiation, and useful applications of bacterial products. Sequencing of whole bacterial genomes and the experimental approaches made possible by accessibility to the sequences have brought a new perspective to microbiology. Focussing on issues of gene organization, regulation, and evolution in the context of the whole life of the cell, this new volume complements the editors' classic 1993 volume Bacillus subtilis and Other Gram-Positive Bacteria. Building upon the previous edition, Bacillus subtilis and Its Closest Relatives contains an updated annotation of the complete B. subtilis genome and includes a unique compilation of major pathways of metabolism and macromolecular synthesis, correlating genes and proteins and assigning new functions to many genes. It also provides clear explanations of the major regulatory mechanisms that are unique to

Table of Contents

Contributors	ix
Preface	xv
BACILLUS SUBTILIS: A GENOMIC VIEW
Bacillus subtilis: from Cells to Genes and from Genes to Cells	1	(6)
Abraham L. Sonenshein
James A. Hoch
Richard Losick
The Bacillus subtilis Genome, Genes, and Functions	7	(8)
Ivan Moszer
CELL ARCHITECTURE
The Dynamic Architecture of the Bacillus Cell	15	(6)
Marc D. Sharp
Kit Pogliano
Structure and Synthesis of Cell Wall, Spore Cortex, Teichoic Acids, S-Layers, and Capsules	21	(22)
Simon J. Foster
David L. Popham
Biosynthesis and Function of Membrane Lipids	43	(14)
Diego de Mendoza
Gustavo E. Schujman
Pablo S. Aguilar
Cell Wall-Anchored Surface Proteins and Lipoproteins of Gram-Positive Bacteria	57	(16)
Sarkis K. Mazmanian
Olaf Schneewind
CHROMOSOME REPLICATION AND CELL DIVISION
Chromosome Replication and Segregation	73	(14)
Katherine P. Lemon
Shigeki Moriya
Naotake Ogasawara
Alan D. Grossman
Termination of Chromosome Replication	87	(10)
I. G. Duggin
R. G. Wake
Cell Division during Growth and Sporulation	97	(16)
Jeff Errington
Richard A. Daniel
METABOLISM AND ITS REGULATION
Overview of Transport in Bacillus subtilis	113	(16)
Milton H. Saier, Jr.
Seth R. Goldman
Randal R. Maile
Matthew S. Moreno
Walter Weyler
Nelson Yang
Ian T. Paulsen
Carbohydrate Uptake and Metabolism	129	(22)
Josef Deutscher
Anne Galinier
Isabelle Martin-Verstraete
The Krebs Citric Acid Cycle	151	(12)
Abraham L. Sonenshein
Respiratory Cytochromes, Other Heme Proteins, and Heme Biosynthesis	163	(18)
Claes Von Wachenfeldt
Lars Hederstedt
Nitrogen Source Utilization and Its Regulation	181	(12)
Susan H. Fisher
Michel Debarbouille
The Pho Regulon	193	(10)
F. Marion Hulett
Biosynthesis of Amino Acids of the Glutamate and Aspartate Families, Alanine, and Polyamines	203	(30)
Boris R. Belitsky
Aromatic Amino Acid Metabolism in Bacillus subtilis	233	(12)
Paul Gollnick
Paul Babitzke
Enrique Merino
Charles Yanofsky
Synthesis of Serine, Glycine, Cysteine, and Methionine	245	(10)
Frank J. Grundy
Tina M. Henkin
Purine, Pyrimidine, and Pyridine Nucleotide Metabolism	255	(16)
Robert L. Switzer
Howard Zalkin
Hans Henrik Saxild
Vitamin Biosynthesis	271	(18)
John B. Perkins
Janice Pero
MACROMOLECULAR SYNTHESIS
RNA Polymerase and Sigma Factors	289	(24)
John D. Helmann
Charles P. Moran, Jr
Ribosomes, Protein Synthesis Factors, and tRNA Synthetases	313	(10)
Tina M. Henkin
Regulation by Termination-Antitermination: a Genomic Approach	323	(14)
Enrique Merino
Charles Yanofsky
Protein Transport Pathways in Bacillus subtilis: a Genome-Based Road Map	337	(22)
Jan Maarten Van Dijl
Albert Bolhuis
Harold Tjalsma
Jan D. H. Jongbloed
Anne De Jong
Sierd Bron
ADAPTATION AND DIFFERENTIATION
Regulation and Function of Heat-Inducible Genes in Bacillus subtilis	359	(10)
Wolfgang Schumann
Michael Heckler
Tarek Msadek
General Stress Response	369	(16)
Chester W. Price
Adaptation to Changing Osmolarity	385	(8)
Erhard Bremer
Anaerobiosis	393	(12)
Michiko M. Nakano
Peter Zuber
Metal Ion Uptake and Oxidative Stress	405	(10)
Andrew F. Herbig
John D. Helmann
Nonribosomal Assembly of Peptide Antibiotics on Modular Protein Templates	415	(22)
Torsten Stachelhaus
Henning D. Mootz
Mohamed A. Marahiel
Chemotaxis and Motility	437	(16)
Shin-Ichi Aizawa
Igor B. Zhulin
Leticia Marquez-Magana
George W. Ordal
Transformation and Recombination	453	(20)
David Dubnau
Charles M. Lovett, Jr
Two-Component Systems, Phosphorelays, and Regulation of Their Activities by Phosphatases	473	(10)
Marta Perego
James A. Hoch
Sporulation Genes and Intercompartmental Regulation	483	(36)
Patrick J. Piggot
Richard Losick
A Gene Odyssey: Exploring the Genomes of Endospore-Forming Bacteria	519	(8)
Patrick Stragier
Proteins of the Spore Coat and Coat	527	(10)
Adam Driks
Spore Germination and Outgrowth	537	(12)
Madan Paidhungat
Peter Setlow
Color Plates	549	(3)
Appendix 1: General View of the Bacillus subtilis Chromosome	552	(18)
Appendix 2: Functional Classification of the Bacillus subtilis Protein-Encoding Genes	570	(47)
Index	617