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Basic and Clinical Pharmacology



Pub. Date:
Appleton & Lange
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The most current, authoritative, and comprehensive pharmacology book for medical, pharmacy, and other health science students. Widely respected for its clarity, comprehensiveness, and organization, this pharmacology course book presents the essential concepts that students need to know about the science of pharmacology and their application.

Table of Contents

Schedule of Controlled Drugsp. Inside Front
Prefacep. ix
Authorsp. xi
Basic Principlesp. 1
Introductionp. 1
Drug Receptors & Pharmacodynamicsp. 11
Pharmacokinetics & Pharmacodynamics: Rational Dosing & the Time Course of Drug Actionp. 34
Drug Biotransformationp. 51
Basic & Clinical Evaluation of New Drugsp. 64
Autonomic Drugsp. 75
Introduction to Autonomic Pharmacologyp. 75
Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugsp. 94
Cholinoceptor-Blocking Drugsp. 109
Adrenoceptor-Activating & Other Sympathomimetic Drugsp. 122
Adrenoceptor Antagonist Drugsp. 142
Cardiovascular-Renal Drugsp. 160
Antihypertensive Agentsp. 160
Vasodilators & the Treatment of Angina Pectorisp. 184
Drugs Used in Heart Failurep. 201
Agents Used in Cardiac Arrhythmiasp. 216
Diuretic Agentsp. 241
Drugs With Important Actions on Smooth Musclep. 259
Histamine, Serotonin, & the Ergot Alkaloidsp. 259
Vasoactive Peptidesp. 281
The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compoundsp. 298
Nitric Oxide, Donors, & Inhibitorsp. 313
Drugs Used in Asthmap. 319
Drugs That Act in the Central Nervous Systemp. 336
Introduction to the Pharmacology of CNS Drugsp. 336
Sedative-Hypnotic Drugsp. 351
The Alcoholsp. 367
Antiseizure Drugsp. 379
General Anestheticsp. 401
Local Anestheticsp. 418
Skeletal Muscle Relaxantsp. 428
Pharmacologic Management of Parkinsonism & Other Movement Disordersp. 447
Antipsychotic Agents & Lithiump. 462
Antidepressant Agentsp. 482
Opioid Analgesics & Antagonistsp. 497
Drugs of Abusep. 517
Drugs Used to Treat Diseases of the Blood, Inflammation, & Goutp. 529
Agents Used in Anemias; Hematopoietic Growth Factorsp. 529
Drugs Used in Disorders of Coagulationp. 543
Agents Used in Hyperlipidemiap. 561
Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Goutp. 576
Endocrine Drugsp. 604
Hypothalamic & Pituitary Hormonesp. 604
Thyroid & Antithyroid Drugsp. 625
Adrenocorticosteroids & Adrenocortical Antagonistsp. 641
The Gonadal Hormones & Inhibitorsp. 661
Pancreatic Hormones & Antidiabetic Drugsp. 693
Agents That Affect Bone Mineral Homeostasisp. 716
Chemotherapeutic Drugsp. 733
Beta-Lactam Antibiotics & Other Inhibitors of Cell Wall Synthesisp. 734
Chloramphenicol, Tetracyclines, Macrolides, Clindamycin, & Streptograminsp. 754
Aminoglycosides & Spectinomycinp. 764
Sulfonamides, Trimethoprim, & Quinolonesp. 773
Antimycobacterial Drugsp. 782
Antifungal Agentsp. 792
Antiviral Agentsp. 801
Miscellaneous Antimicrobial Agents; Disinfectants, Antiseptics, & Sterilantsp. 828
Clinical Use of Antimicrobial Agentsp. 836
Basic Principles of Antiparasitic Chemotherapyp. 852
Antiprotozoal Drugsp. 864
Clinical Pharmacology of the Anthelmintic Drugsp. 886
Cancer Chemotherapyp. 898
Immunopharmacologyp. 931
Toxicologyp. 958
Introduction to Toxicology: Occupational & Environmentalp. 958
Heavy Metal Intoxication & Chelatorsp. 970
Management of the Poisoned Patientp. 982
Special Topicsp. 995
Special Aspects of Perinatal & Pediatric Pharmacologyp. 995
Special Aspects of Geriatric Pharmacologyp. 1007
Dermatologic Pharmacologyp. 1015
Drugs Used in the Treatment of Gastrointestinal Diseasesp. 1034
Therapeutic & Toxic Potential of Oyer-the-Counter Agentsp. 1064
Botanicals ("Herbal Medications") & Nutritional Supplementsp. 1076
Rational Prescribing & Prescription Writingp. 1091
Vaccines, Immune Globulins, & Other Complex Biologic Productsp. 1101
Important Drug Interactions & Their Mechanismsp. 1110
Indexp. 1125
Table of Contents provided by Rittenhouse. All Rights Reserved.

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