Behavioral Genetics of the Mouse

by Crusio, Wim E.; Slyuter, Frans; Gerlai, Robert T.; Pietropaolo, Susanna

• ISBN13: 9781107034815
• ISBN10: 1107034817
• Format: Hardcover
• Copyright: 2013-06-30
• Publisher: Cambridge Univ Pr

Summary

The first volume in the new Cambridge Handbooks in Behavioral Genetics series, Behavioral Genetics of the Mouse provides baseline information on normal behaviors, essential in both the design of experiments using genetically modified or pharmacologically treated animals and in the interpretation and analyses of the results obtained. The book offers a comprehensive overview of the genetics of naturally occurring variation in mouse behavior, from perception and spontaneous behaviors such as exploration, aggression, social interactions and motor behaviors, to reinforced behaviors such as the different types of learning. Also included are numerous examples of potential experimental problems, which will aid and guide researchers trying to troubleshoot their own studies. A lasting reference, the thorough and comprehensive reviews offer an easy entrance into the extensive literature in this field, and will prove invaluable to students and specialists alike.

Table of Contents

Contributor list

General:

Current status of the field

Natural neurobiology and behavior of the mouse: relevance for behavioral studies in the laboratory

Ethogram

Replicability and reliability of behavioral tests

Perception:

Audition

Behavioral measurement of mouse visual function

Tactile system and nociception

Olfactory acuity in Mus musculus

Taste genetics

Autonomous and Motor Behaviors:

Motor coordination in inbred mouse strains and the crucial role of the cerebellum

Reflex development

Feeding and drinking

Lateralization

Rhythms and sleep: circadian and seasonal activity patterns

Exploratory behavior

Strains, SNPs and selected lines: genetic factors influencing variation in murine anxiety-like behavior

Genetic influences on infant mouse ultrasonic vocalizations

Startle behavior and prepulse inhibition

Mouse models of stress-induced depression-like behavior: stress vulnerability and antidepressant response as traits

Behavioral phenotyping of mouse grooming and barbering

Social Behavior:

Social interaction

Mouse sex: sexual differentiation and sexual behavior in Mus musculus

Nest-building behavior and the genetic correlation structure of adaptive phenotypes in house mice

Aggression

Learning and Memory:

Latent inhibition

Executive function: response inhibition, attention, and cognitive flexibility

Water navigation tasks

Active and passive avoidance

Radial maze

Other mazes

Cued and contextual fear conditioning

Taste and odor

Object recognition in the mouse

Index

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