Behavioral Genetics of the Mouse: Volume 1, Genetics of Behavioral Phenotypes

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  • Format: Hardcover
  • Copyright: 6/30/2013
  • Publisher: Cambridge Univ Pr
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The first volume in the new Cambridge Handbooks in Behavioral Genetics series, Behavioral Genetics of the Mouse provides baseline information on normal behaviors, essential in both the design of experiments using genetically modified or pharmacologically treated animals and in the interpretation and analyses of the results obtained. The book offers a comprehensive overview of the genetics of naturally occurring variation in mouse behavior, from perception and spontaneous behaviors such as exploration, aggression, social interactions and motor behaviors, to reinforced behaviors such as the different types of learning. Also included are numerous examples of potential experimental problems, which will aid and guide researchers trying to troubleshoot their own studies. A lasting reference, the thorough and comprehensive reviews offer an easy entrance into the extensive literature in this field, and will prove invaluable to students and specialists alike.

Table of Contents

Contributor list
Current status of the field
Natural neurobiology and behavior of the mouse: relevance for behavioral studies in the laboratory
Replicability and reliability of behavioral tests
Behavioral measurement of mouse visual function
Tactile system and nociception
Olfactory acuity in Mus musculus
Taste genetics
Autonomous and Motor Behaviors:
Motor coordination in inbred mouse strains and the crucial role of the cerebellum
Reflex development
Feeding and drinking
Rhythms and sleep: circadian and seasonal activity patterns
Exploratory behavior
Strains, SNPs and selected lines: genetic factors influencing variation in murine anxiety-like behavior
Genetic influences on infant mouse ultrasonic vocalizations
Startle behavior and prepulse inhibition
Mouse models of stress-induced depression-like behavior: stress vulnerability and antidepressant response as traits
Behavioral phenotyping of mouse grooming and barbering
Social Behavior:
Social interaction
Mouse sex: sexual differentiation and sexual behavior in Mus musculus
Nest-building behavior and the genetic correlation structure of adaptive phenotypes in house mice
Learning and Memory:
Latent inhibition
Executive function: response inhibition, attention, and cognitive flexibility
Water navigation tasks
Active and passive avoidance
Radial maze
Other mazes
Cued and contextual fear conditioning
Taste and odor
Object recognition in the mouse
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