Biochemistry

by Marks, Dawn B.

• ISBN13: 9780683304916
• ISBN10: 0683304917
• Edition: 3rd
• Format: Paperback
• Copyright: 1998-11-01
• Publisher: Lippincott Williams & Wilkins

Summary

BRS Biochemistry embodies the popular BRS format of succinct outline review of content followed by approximately 500 USMLE-style questions with explanations. This current edition has numerous illustrations and contains notable review features such as summary boxes. The overall content and questions have been updated to reflect the evolving nature of USMLE.

Table of Contents

Preface	ix
Acknowledgments	xi
Fuel Metabolism	1	(16)
Overview	1	(1)
Metabolic fuels and dietary components	1	(3)
The fed or absorptive state	4	(3)
Fasting	7	(2)
Prolonged fasting (starvation)	9	(1)
Clinical correlations	10	(3)
Review test	13	(4)
Basic Aspects of Biochemistry	17	(28)
Overview	17	(1)
Brief review of organic chemistry	17	(1)
Acids, bases, and buffers	18	(2)
Amino acids and peptide bonds	20	(4)
Protein structure	24	(6)
Enzymes	30	(5)
Clinical correlations	35	(2)
Review test	37	(8)
Gene Expression and the Synthesis of Proteins	45	(60)
Overview	45	(1)
Nucleic acid structure	45	(7)
Synthesis of DNA (replication)	52	(8)
Synthesis of RNA (transcription)	60	(5)
Protein synthesis (translation of mRNA)	65	(6)
Regulation of protein synthesis	71	(8)
Biotechnology involving recombinant DNA	79	(9)
Clinical correlations	88	(3)
Review test	91	(14)
Generation of ATP from Metabolic Fuels	105	(30)
Overview	105	(1)
Bioenergetics	106	(2)
Properties of adenosine triphosphate	108	(1)
Electron carriers and vitamins	109	(8)
TCA cycle	117	(5)
Electron transport chain and oxidative phosphorylation	122	(4)
Clinical correlations	126	(2)
Review test	128	(7)
Carbohydrate Metabolism	135	(58)
Overview	135	(1)
Carbohydrate structure	135	(5)
Proteoglycans, glycoproteins, and glycolipids	140	(3)
Digestion of carbohydrates	143	(3)
Glycogen structure and metabolism	146	(7)
Glycolysis	153	(8)
Gluconeogenesis	161	(6)
Fructose and galactose metabolism	167	(3)
Pentose phosphate pathway	170	(3)
Maintenance of blood glucose levels	173	(5)
Clinical correlations	178	(3)
Review test	181	(12)
Lipid Metabolism	193	(44)
Overview	193	(1)
Lipid structure	194	(1)
Membranes	195	(1)
Digestion of dietary triacylglycerol	196	(2)
Fatty acid and triacylglycerol synthesis	198	(6)
Formation of triacylglycerol stores in adipose tissue	204	(1)
Cholesterol and bile salt metabolism	205	(3)
Blood lipoproteins	208	(4)
Fate of adipose triacylglycerols	212	(1)
Fatty acid oxidation	213	(4)
Ketone body synthesis and utilization	217	(2)
Phospholipid and sphingolipid metabolism	219	(3)
Metabolism of the eicosanoids	222	(2)
Clinical correlations	224	(3)
Review test	227	(10)
Nitrogen Metabolism	237	(46)
Overview	237	(1)
Protein digestion and amino acid absorption	237	(4)
Addition and removal of amino acid nitrogen	241	(2)
Urea cycle	243	(3)
Synthesis and degradation of amino acids	246	(6)
Interrelationships of various tissues in amino acid metabolism	252	(4)
Tetrahydrofolate, vitamin B12, and S-adenosylmethionine	256	(4)
Special products derived from amino acids	260	(9)
Clinical correlations	269	(4)
Review test	273	(10)
Molecular Endocrinology	283	(26)
Overview	283	(1)
Synthesis of hormones	284	(1)
General mechanisms of hormone action	285	(6)
Regulation of hormone levels	291	(2)
Actions of specific hormones	293	(7)
Clinical correlations	300	(9)
Review test	303	(6)
The Biochemical Functions of Tissues and Their Clinical Implications	309	(12)
Overview	309	(1)
Use of biochemical measurements to diagnose pathologic conditions	309	(1)
Biochemical functions of tissues	310	(11)
Comprehensive Examination	321	(24)
Index	345