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9783540285434

35th Hemophilia Symposium

by
  • ISBN13:

    9783540285434

  • ISBN10:

    3540285431

  • Edition: 1st
  • Format: Paperback
  • Copyright: 2005-12-01
  • Publisher: SPRINGER

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Supplemental Materials

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Summary

This book contains the contribution to the 35th Hemophilia Symposium, Hamburg 2004. The main topics are epidemiology, risk of infections and inhibitors in hemophilia, chronic hemophilic synovitis and long-term results of orthopedic treatment, laboratory diagnostics and pediatric hemostaseology. The volume is rounded off by numerous free papers and posters on hemophilia and hemorrhagic disorders and inhibitors in hemophilia.

Table of Contents

Johann Lukas Schoenlein Prize 2004
I. SCHARRER
XXXI
I. Epidemiology
HIV Infection and Causes of Death in Patients with Hemophilia in Germany (Year 2003/2004 Survey)
W. SCHRAMM, H. KREBS, on behalf of the participating German hemophilia centers
3(10)
Hemophilia Registry of the Medical Committee of the Swiss Hemophilia Association - Update and Annual Survey 2004
S. HARTMANN, K. LOCHER
13(8)
II. Risk of Infections and Inhibitors in Hemophilia
Update on the Safety of Clotting Factors, Mainly Regarding the Risk of Transmission of vCJD (Variant Creutzfeldt Jakob Disease)
L.G. GÜRTLER
21(8)
nvCJD and Blood Products in the UK
P.L.F. GIANGRANDE
29(4)
Mutation Type Dependent Inhibitor Risk - a Single Center Study on 432 Patients with Severe Hemophilia A
J. OLDENBURG, J. SCHRÖDER, R. SCHWAAB, C. MÜLLER-REIBLE, E. SEIFRIED, P. HANFLAND, H.-H. BRACKMANN
33(1)
Inhibitor Incidence in Previously Untreated Patients (PUPs) with Hemophilia A and B. A Prospective Multi-Center Study of the Pediatric Committee of the German, Swiss and Austrian Society for Thrombosis and Hemostasis Research (GTH)
W. KREUZ, G. AUERSWALD, U. BUDDE, H. J. KLOSE, H. LENK and the GTH-PUP-Study-Group
34(4)
A DVATE Inhibitor Risk Profile: 18 Months post-Licensure
E. GOMPERTS
38(4)
EACH-Registry: An European Registry for Acquired Hemophilia
A. HUTH-KÜHNE, P. LAGES, R. FISCHER, R. ZIMMERMANN
42(2)
Elective Orthopedic Surgery for Hemophilia Patients with Inhibitors
P.L.F. GIANGRANDE
44(5)
III. Chronic Synovitis and Long-term Results of Orthopedic Treatment
Results after Total Knee and Hip Replacement in Patients with Hemophilia A - A Single Center Experience
R. KLAMROTH, CH. HEINRICHS, S. GOTTSTEIN, R. KOCH
49(3)
Motion Analysis Epidemiology in Hemophilic Children
A. SEUSER, G. SCHUMPE, T. WALLNY, H.-H. BRACKMANN
52(5)
Radiosynoviorthesis in Hemophilic Arthropathy - A Single Center Experience
S. GOTTSTEIN, R. KLAMROTH
57(4)
IV. Laboratory Diagnostics: Coagulation Factors, Inhibitors, Monitoring
Individual Therapy of Hemophilia - New Laboratory Methods Considering Platelets
TH. SIEGEMUND, A. SIEGEMUND, S. BASSUS, W. WEGERT, S. PETROS, U. SCHOLZ, L. ENGELMANN
61(5)
Epitope Mapping during FVIII Inhibitor Elimination with Rituximab Reveals Conformational Epitopes on FVIII and Identifies Small Molecules Blocking Inhibitor and Targeting B Cells
C. KESSEL, C. KÖNIGS, R. LINDE, C. ESCURIOLA-ETTINGSHAUSEN, J. ROLAND, H. STOLL, T. KLINGEBIEL, U. DIETRICH, W. KREUZ
66(15)
Lack of Factor VIII Expression Represents a Novel Mechanism Leading to Hemophilia A
O. EL-MAARRI, H. SINGER, H.-H. BRACKMANN, SCHRÖDER, T. GRAW, C.R. MÜLLER, W. SCHRAMM, R. SCHWAAB, P. HANFLAND, J. OLDENBURG
81(6)
V. Pediatric Hemostaseology
Effects of the Factor V G1691A Mutation and the Factor II G20210A Variant on the Clinical Expression of Severe Hemophilia A (less than 2%) in Children -Results of a Multicenter Study
K. KURNIK, C. ESCURIOLA-ETTINGSHAUSEN, S. HORNEFF, C. DÜRING, R. SCHOBESS, C. BIDLINGMAIER, S. HALIMEH, H. POLLMANN, N. BOGDANOVA, U. NOWAK-GÖTTL
87(8)
Continuous Infusion of Factor Concentrates in Children with Hemophilia A in Comparison to Bolus Injections
C. BIDLINGMAIER, M. DEML, K. KURNIK
95(7)
Decreased Clotting Factor Activity (VIII, IX, XI, and XII) due to Inhibitors with Lupus-like Activity in Childhood
V. AUMANN, L. WIENS, G. LUTZE, U. MITTLER
102(7)
VI. Free Lectures
Effect of Activated Recombinant Coagulation Factor VII on the Function of Glycoprotein IIb/IIIa-Inhibited Platelets in Vitro
M. UDVARDY
109(11)
Mutation Analysis in Hereditary Angioedema Identifies Patients at Risk for Developing Acute and Life Threatening Edema
T. FÖRSTER, A. KOCOT, J. SCHRÖDER, W. KREUZ, E. AYGÖREN-PÜRSÜN, I. MARTINEZ-SAGUER, K. BORK, I. SCHARRER, C. MÜLLER, J. OLDENBURG
120(3)
Recurrent Mutation in ADAMTS13 Gene as a Cause of a Hereditary Thrombotic Thrombocytopenic Purpura in the Czech Republic
I. HRACHOVINOVÁ, P. SALAJ, J. SUTTNAR, Š. RITTICH, P. JINOCH, T. ŠULÁKOVÁ, J. PTÁK, P. DULICEK, T. SEEMAN
123(3)
Clinical Manifestations of Patients with Dysfibrinogenemia
W. MIESBACH, V. CATANIA, M. BOEHM, TH. VIGH, I. SCHARRER
126(4)
Case Report of a FXIII Inhibitor in a 77-year-old Patient
W. MIESBACH, M. BOEHM, CH. VON AUER, I. SCHARRER
130(5)
VII. Poster
a) Hemophilia and Hemorrhagic Disorders
The ABC's of Hemophilia
German Working Group of Hemophilia Nurses
135(1)
The Long Journey to Being Diagnosed as a Carrier of Hemophilia A - A Woman with Abnormally Prolonged Bleeding after Myocardial Infarction
W. MIESBACH, B. PUTZ, CH. VON AUER, I. SCHARRER
136(2)
Clinical Investigation of Orthopedic Outcome in Patients with Severe Hemophilia - Advantage of an Early Prophylactic Treatment?
S. MEISTER, K. CHRISTENSEN, A. WEIDENHAMMER, T. SPRANGER, G. AUERSWALD
138(4)
The Relevance of Thrombophilic Risk Factors on Bleeding Tendency in Hemophilia A Patients
M. KRAUSE, A. HAHN, F. PEYVANDI, I. SCHARRER
142(2)
Magnetic Field Therapy in Patients with Severe Hemophilia - Motion Analysis and Quality Control
A. SEUSER, G. SCHUMPE, T. WALLNY, H.-H. BRACKMANN
144(6)
The Clinical Course of two Patients Receiving High Dose Factor VIII -Replacement Therapy
K.H. BECK, M. MOHRMANN
150(3)
Determination of the Factor VIII Plasma Activity of Hemophilia A Patients Treated with a New Recombinant Factor VIII Concentrate
K.-W. VON PAPE, R. KLAMROTH, U. KYANK, J. BOHNER
153(4)
Socio-Economic Aspects of Hemophilia Treatment in Romania
D. MIHAILOV, M. SERBAN, B. LIPPERT, W. SCHRAMM, S. ARGHIRESCU
157(8)
Immunosuppressive Treatment in Acquired von Willebrand's Syndrome
H.-H. WOLF, A. HARBA, A. FRÜHAUF, H.-J. SCHMOLL
165(3)
HCV-Infection in HIV-Infected and Non-Infected People with Hemophilia -A Retrospective Study: Medical Aspects
H. KREBS, M.M. SCHNEIDER, W. SCHRAMM
168(5)
HCV-Infection in HIV-Infected and Non-Infected People with Hemophilia -A Retrospective Study: Psychosocial Aspects
M.M. SCHNEIDER, H. KREBS, W. SCHRAMM
173(6)
Testing Factor VIII Activity by Using the Chromogenic Assay in Carriers of Hemophilia A
W. MIESBACH, TH. VIGH, I. SCHARRER
179(4)
Hip Replacement in Hemophilic Patients - A 30 Years Single Center Experience
A. KURTH, CH. EBERHARDT, L. HOVY, M. KRAUSE, I. SCHARRER
183(4)
b) Inhibitors in Hemophilia
Successful Therapy with anti CD20 Monoclonal Antibody Rituximab in Patients with Acquired Hemophilia against Factor VIII
M. KRAUSE, CH. VON AUER, I. STIER-BRUCK, I. SCHARRER
187(3)
Unusual Prolonged Course of an Immune Tolerance Therapy (ITT) in a Patient with Severe Hemophilia A and a High-Titer Inhibitor Development
S. MEISTER, T. SPRANGER, K. CHRISTENSEN, H.-H. BRACKMANN, G. AUERSWALD
190(4)
Successful Major Surgery with Minimal Dosage of rFVIIa in a Hemophilia A Patient with High Level of Alloantibodies to Factor VIII
M. SERBAN, P. TEPENEU, S. ARGHIRESCU, R. BADETI, C. JINCA, D. MIHAILOV, D. LIGHEZAN, W. SCHRAMM
194(4)
Inhibitor Development after Continuous Infusion of Factor VIII: A Retrospective Study in Germany
CH. VON AUER, J. OLDENBURG, M. KRAUSE, W. MIESBACH, I. SCHARRER and CI-Study Group
198(3)
Inhibitors in PTP'S: A Retrospective Study in Germany
CH. VON AUER, J. OLDENBURG, M. KRAUSE, W. MIESBACH, I. SCHARRER and PTP-Study Group
201(4)
Elective Orthopedic Surgery in Inhibitor Patients - the Frankfurt Concept
A. KURTH, U. STUMPF, B. HABERMANN, M. KRAUSE, I. SCHARRER
205(4)
c) Clinic and Casuistics
The Frequency of Venous Thromboembolism in Women with FV Leiden in Association with Pregnancy and Puerperium
P. DULICEK, J. MALY M. PECKA, M. BERÁNEK
209(6)
d) Diagnostics
Spectrum of Molecular Defects and Mutation Detection Date in Patients with Severe Hemophilia A
N. BOGDANOVA, A. MARKOFF, U. NOWAK-GÖTTL, R. EISERT, C. WERMES, H. POLLMANN, A. TODOROVA, A. EIGEL, B. DWORNICZAK, J. HORST
215(4)
Hemophilia Patients and Prothrombotic Gene Mutation
A. HLUSI, V. KRCOVÁ, P. NOVÁK, L. SLAVIK
219(2)
γAla82Gly Represents a Common Fibrinogen Chain Variant in Caucasians
V. IVASKEVICIUS, E. JUSCIUTE, M. STEFFENS, CH. GEISEN, P. HANFLAND, TH. F. WIENKER, E. SEIFRIED, J. OLDENBURG
221(5)
A Novel Mutation (Asp36Tyr) in the Vitamin K Epoxide Reductase Complex Subunit 1 Gene (VKORC1) Causes Increased Phenprocoumon Requirement
C. GEISEN, G. SPOHN, K. SITTINGER, S. ROST, M. WATZKA, P. LAGES, A. HUTH-KÜHNE, R. ZIMMERMANN, C.R. MÜLLER, E. SEIFRIED, J. OLDENBURG
226(4)
Denaturing High Performance Liquid Chromatography Represents an Efficient Technique for Detection of Heterozygous Large Deletions in Antithrombin Gene
A. PAVLOVA, O. EL-MAARRI, B. LUXEMBOURG, E. LINDHOFF-LAST, D. DELEV, M. WATZKA, E. SEIFRIED, J. OLDENBURG
230(5)
e) Miscellaneous
Recurrent Coronary Stent Thrombosis in a Patient with Combined Aspirin and Clopidogrel Resistance
CH. TEMPLIN, A. SCHAEFER, B. STUMME, H. DREXLER, M. VON DEPKA PRONDZINSKI
235(4)
Coagulation Factor XIII Mutation Profile: Update 2004
V. IVASKEVICIUS, R. SEITZ, H.-H. BRACKMANN, W. EBERL, K. KURNIK, W. KREUZ, R. KLAMROTH, H. ROTT, R.M. LORETH, F. HERRMANN, E. SEIFRIED, J. OLDENBURG
239(3)
Site-Directed Mutagenesis of VKORC1, the Target Protein of Coumarin-Type Anticoagulants
S. ROST, A. FREGIN, M. HÜNERBERG, C.R. MÜLLER, J. OLDENBURG
242(3)
Treatment of Dilution Coagulopathy by Fibrinogen and Platelet Concentrates
C. DE LORENZO, M. SPANNAGL, B. HEINDL
245(2)
Pathogenesis of Hepatic Veno-Occlusive Disease in Patients Undergoing Hematopoietic Stem Cell Transplantation
M. DÁVID, O. TÓTH, Á. NAGY, B. MENG, J. TÁBORI, H. LOSONCZY
247(12)
Subject Index 259

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