Bovine Genomics

by Womack, James

• ISBN13: 9780813821221
• ISBN10: 0813821223
• Edition: 1st
• Format: Hardcover
• Copyright: 2012-06-26
• Publisher: Wiley-Blackwell

Summary

Bovine Genomics provides a thorough overview of bovine genetics and genomics in the post-sequencing era. Covering the topic from its roots in quantitative genetic through to applications of the most up-to-date technologies, this volume will serve as a definitive source of information on bovine genomics. Bovine Genomics opens with chapters that look at the origins of cattle domestication and Mendelian inheritance of key traits, then transitions from quantitative genetics to genomics, with six chapters spanning the mapping to sequencing phases of bovine genome research making up the core of the book. The final section focuses on applications of genomic information, including informatics, QTL mapping, marker assisted selection, and the application of genomics to gene discovery. Bovine Genomics will be an essential resource for all researchers and professional working in the livestock and genomics fields.

Author Biography

James E. Womack is the W. P. Luse Endowed and Distinguished Professor of Veterinary Pathobiology at Texas AM University and Professor of Animal Genetics and Disease, WCU Biomodulation Program, Seoul National University.

Table of Contents

List of Contributors	p. vii
Foreword	p. ix
The Origins of Cattle	p. 1
Mendelian Inheritance in Cattle	p. 11
Genetics of Coat Color in Cattle	p. 20
From Quantitative Genetics to Quantitative Genomics: A Personal Odyssey	p. 34
Cartography of the Bovine Genome	p. 51
History of Linkage Mapping the Bovine Genome	p. 63
Bovine X and Y Chromosomes	p. 75
Cattle Comparative Genomics and Chromosomal Evolution	p. 101
Sequencing the Bovine Genome	p. 109
Bovine Genome Architecture	p. 123
Bovine Epigenetics and Epigenomics	p. 144
Mapping Quantitative Trait Loci	p. 169
Genome-Wide Association Studies and Linkage Disequilibrium in Cattle	p. 192
Genomic Selection in Beef Cattle	p. 211
Impact of High-Throughput Genotyping and Sequencing on the Identification of Genes and Variants Underlying Phenotypic Variation in Domestic Cattle	p. 234
Index	p. 259
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