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| Introduction to the Study of Cell and Molecular Biology | |
| The Discovery of Cells | |
| Basic Properties of Cells | |
| Two Fundamentally Different Classes of Cells | |
| Viruses | |
| The Chemical Basis of Life | |
| Covalent Bonds | |
| Noncovalent Bonds | |
| Acids, Bases, and Buffers | |
| The Nature of Biological Molecules | |
| Four Types of Biological Molecules | |
| The Formation of Complex Macromolecular Structures | |
| Bioenergetics, Enzymes, and Metabolism | |
| Bioenergetics | |
| Enzymes as Biological Catalysts | |
| Metabolism | |
| The Structure of Function of the Plasma Membrane | |
| An Overview of Membrane Functions | |
| A Brief History of Studies on Plasma Membrane Structure | |
| The Chemical Composition of Membranes | |
| The Structure and Functions of Membrane Proteins | |
| Membrane Lipids and Membrane Fluidity | |
| The Dynamic Nature of the Plasma Membrane | |
| The Movement of Substances Across Cell Membranes | |
| Membrane Potentials and Nerve Impulses | |
| Aerobic Respiration and the Mitochondrion | |
| Mitochondrial Structure and Function | |
| Oxidative Metabolism in the Mitochondrion | |
| The Role of Mitochondria in the Formation of ATP | |
| Translocation of Protons and Establishment of a Proton-Motive Force | |
| The Machinery for ATP Formation | |
| Peroxisomes | |
| Photosynthesis and the Chloroplast | |
| Chloroplast Structure and Function | |
| An Overview of Photosynthetic Metabolism | |
| The Absorption of Light | |
| Photosynthetic Units and Reaction Centers | |
| Photophosphorylation | |
| Carbon Dioxide Fixation and the Synthesis of Carbohydrate | |
| Interactions Between Cells and Their Environment | |
| The Extracellular Space | |
| Interactions of Cells With Extracellular Materials | |
| Interactions of Cells With Other Cells | |
| Tight Junctions: Sealing the Extracellular Space | |
| GAP Junctions and Plasmodesmata: Mediating Intercellular Communication | |
| Cytoplasmic Membrane Systems: Structure, Function, and Membrane Trafficking | |
| An Overview of the Endomembrane System | |
| A Few Approaches to the Study of Endomembranes | |
| The Endoplasmic Reticulum | |
| The Golgi Complex | |
| Types of Vesicle Transport and Their Functions | |
| Lysosomes | |
| Plant Cell Vacuoles | |
| The Endocytic Pathway: Moving Membrane and Materials into the Cell Interior | |
| Posttranslational Uptake of Proteins By Peroxisomes, Mitochondria, and Chloroplasts | |
| The Cytoskeleton and Cell Motility | |
| Overview of the Major Functions of the Cytoskeleton | |
| The Study of the Cytoskeleton | |
| Microtubules | |
| Intermediate Filaments | |
| Microfilaments | |
| Muscle Contractility | |
| Nonmuscle Motility | |
| The Nature of the Gene and the Genome | |
| The Concept of a Gene as a Unit of Inheritance | |
| Chromosomes: The Physical Carriers of the Genes | |
| The Chemical Nature of the Gene | |
| The Structure of the Genome | |
| The Stability of the Genome | |
| Sequencing Genomes: The Footprints of Biological Evolution | |
| Gene Expression: From Transcription to Translation | |
| The Relationship Between Genes and Proteins | |
| An Overview of Transcription in Both Prokaryotic and Eukaryotic Cells | |
| Synthesis and Processing of Ribosomal and Transfer RNAs | |
| Synthesis and Processing of Messenger RNAs | |
| Small Regulatory RNAs and RNA Silencing Pathways | |
| Encoding Genetic Information | |
| Decoding the Condons: The Role of Transfer RNAs | |
| Translating Genetic Information | |
| The Cell Nucleus and the Control of Gene Expression | |
| The Nucleus of a Eukaryotic Cell | |
| Control of Gene Expression in Bacteria | |
| Control of Gene Expression in Eukaryotes | |
| Transcriptional-Level Control | |
| Processing-Level Control | |
| Translational-Level Control | |
| Postranslational Control Determining Protein Stability | |
| DNA Replication and Repair | |
| DNA Replication | |
| DNA Repair | |
| Between Replication and Repair | |
| Cellular Reproduction | |
| The Cell Cycle | |
| M Phase: Mitosis and Cytokinesis | |
| Meiosis | |
| Cell Signaling and Signal Transduction: Communication Between Cells | |
| The Basic Elements of Cell Signaling Systems | |
| A Survey of Extracellular Messengers and Their Receptors | |
| G Protein-Coupled Receptors and Their Second Messengers | |
| Protein-Tyrosine Phosphorylation as a Mechanism for Signal Transduction | |
| The Role of Calcium as an Intracellular Messenger | |
| Convergence, Divergence, and Crosstalk Among Different Signaling Pathways | |
| The Role of No As An Intercellular Messenger | |
| Apoptosis (Programmed Cell Death) | |
| Cancer | |
| Basic Properties of a Cancer Cell | |
| The Causes of Cancer | |
| The Genetics of Cancer | |
| New Strategies for Combating Cancer | |
| The Immune Response | |
| An Overview of the Immune Response | |
| The Clonal Selection Theory As It Applies To B Cells | |
| T Lymphocytes: Activation and Mechanism of Action | |
| Selected Topics on the Cellular and Molecular Basis of Immunity | |
| Techniques in Cell and Molecular Biology | |
| The Light Microscope | |
| Transmission Electron Microscopy | |
| Scanning Electron and Atomic Force Microscopy | |
| The Use of Radioisotopes | |
| Cell Culture | |
| The Fractionation of a Cell's Contents by Differential Centrifugation | |
| Isolation, Purification, and Fractionation of Proteins | |
| Determining the Structure of Proteins and Multisubunit Complexes | |
| Purification of Nucleic Acids, | |
| Fractionation of Nucleic Acids | |
| Nucleic Acid Hybridization | |
| Chemical Synthesis of DNA | |
| Recombinant DNA Technology | |
| Enzymatic Amplification of DNA by PCR | |
| DNA Sequencing | |
| DNA Libraries | |
| DNA Transfer Into Eukaryotic Cells and Mammalian Embryos | |
| Determining Eukaryotic Gene Function by Gene Elimination or Silencing | |
| The Use of Antibodies | |
| Glossary | |
| Additional Readings | |
| Index | |
| Table of Contents provided by Publisher. All Rights Reserved. |
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