Cerebellar Disorders: A Practical Approach to Diagnosis and Management

by Edited by Mario Ubaldo Manto

• ISBN13: 9780521878135
• ISBN10: 0521878136
• Edition: 1st
• Format: Hardcover
• Copyright: 2010-04-30
• Publisher: Cambridge University Press

Summary

During the last three decades, many laboratories worldwide have dedicated their research activities to understanding the roles of the cerebellum in motor control, cognitive processes and the biology of mental processes, behavioral symptoms and emotion. These advances have been associated with discoveries of new clinical disorders, in particular in the field of genetic ataxias, and the growing number of diseases presents a source of difficulty for clinicians during daily practice. This practical guide summarizes and evaluates current knowledge in the field of cerebellar disorders. Encompassing details of both common and uncommon cerebellar ataxias, including vascular, immune, neoplastic, infectious, traumatic, toxic and inherited disorders, this book will assist clinicians in the diagnosis and management of the full spectrum of cerebellar ataxias encountered in daily practice. Essential reading for clinicians, including general practitioners, neurologists, pediatricians, radiologists, psychiatrists and neuropsychologists, this will also prove a valuable tool for students, trainees and researchers.

Author Biography

Mario Ubaldo Manto is the founding editor of the journal The cerebellum and the founder of the Society for Research on the Cerebellum (SRC).

Table of Contents

Foreword	p. ix
Preface	p. xi
Acknowledgments	p. xii
Introduction	p. 1
Embryology and anatomy	p. 2
Physiology of the cerebellum	p. 23
Symptoms of cerebellar disorders	p. 36
Clinical scales	p. 53
Diagnosis of cerebellar disorders as a function of age	p. 69
Overview of the general management of cerebellar disorders	p. 75
Malformations	p. 78
Cerebellar stroke	p. 88
Immune diseases	p. 102
Endocrine disorders	p. 113
Infectious diseases	p. 118
Corticobasal degeneration	p. 133
Tumors and paraneoplastic disorders	p. 135
Trauma of the posterior fossa	p. 149
Toxic agents	p. 157
Autism spectrum disorders and ataxia	p. 171
Progressive myoclonic epilepsies	p. 174
Multiple system atrophy	p. 179
Essential tremor	p. 184
Autosomal recessive cerebellar ataxias	p. 189
Mitochondrial disorders	p. 229
X-linked ataxias	p. 237
Dominant ataxias	p. 242
Index	p. 284
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