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William Small Jr, MD, Professor of Radiation Oncology, Professor and Chair of the Department of Radiation Oncology, Loyola University Chicago Stritch School of Medicine, Chicago, IL, USA
Associate Editors Nancy J. Tarbell, MD, Dean for Academic and Clinical Affairs and the C.C. Wang Professor of Radiation Oncology, Harvard Medical School, MA, USA
Min Yao, MD, PhD, Department of Radiation Oncology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH, USA
Section Editors Minesh Mehta, MD, Jason A. Efstathiou, MD, and Chis Willet, MD
Dr Chiu-Chen Wang, Founding Editor of Clinical Radiation Oncology
Edited for two successful editions (1988 and 2000) by the eminent physician Dr Chiu-Chen Wang, this book was designed to offer highly practical, application-based comprehensive overview of the biological basis of radiation oncology and the clinical efficacy of radiation therapy. Dr Wang, widely known as "C.C." and well known for his "???skilled and no-nonsense methods of dealing with the various types of major organ cancers," passed away in 2005. He was a highly acclaimed leader in the field of radiation oncology based at Harvard Medical School, which established the "C.C. Wang Professorship in Radiation Oncology."
Dedication ix
Preface xi
Contributors xiii
Section 1 Scientific Foundations 1Section Editor:William Small Jr.
1 Basic Concepts of Clinical Radiation Oncology 3Hannah Yoon, Karan Shah,William Small Jr,Minesh P.Mehta and John P. Hayes
2 Radiation Biology for Radiation Oncologists 15Timothy A. Chan, Boris Hristov and Simon N. Powell
3 Treatment Planning 62George T.Y. Chen and Jong H. Kung
4 Image-Guided Radiation Therapy 83Monique Youl, Kristy K. Brock and Laura A. Dawson
5 A Guide to Understanding Statistics in Radiation Oncology 99Kathryn Winter
6 Use of Protons for Radiation Therapy 115Mark Pankuch, Nasiruddin Mohammed, Draik Hecksel, Steve Laub, Sean Boyer and William F. Hartsell
7 Principles of Palliative Radiation Therapy 141Randy L. Wei, Bo A. Wan, Edward Chowand Stephen Lutz
8 Patient Safety and Quality: Management for the Radiation Oncologist 158Fiori Alite and Abhishek A. Solanki
Section 2 Cancers of the Head and Neck 175Section Editor: Min Yao
9 Carcinoma of the Oral Cavity 177Keith Unger, Felix Ho, James Melotek and Nancy Lee
10 Oropharyngeal Cancer 202Charles Woods, Mitchell Machtay and Min Yao
11 Larynx and Hypopharynx 227Changhu Chen
12 Carcinoma of the Nasopharynx 248Keith Unger, Felix Ho, James Melotek and Nancy Lee
13 Carcinoma of the Paranasal Sinuses and Nasal Cavity 269Farzan Siddiqui, Nicholas Galanopoulos and Min Yao
14 Salivary Gland Carcinomas 288Allen M. Chen
15 Cervical Nodes with Unknown Primary Carcinomas 300Min Yao, Pierre Lavertu and Mitchell Machtay
16 Temporal Bone Tumors 313Allen M. Chen
17 Thyroid Cancer 318Roi Dagan and Robert J. Amdur
18 Head and Neck Radiation Therapy Sequelae and Late Complications and the Role of IMRT 335Xiaoshen Wang and Avraham Eisbruch
Section 3 Cancer of the Intrathorax 349Section Editor: Minesh P. Mehta
19 Lung Cancer 351Deepak Khuntia, Pranshu Mohindra and Minesh P. Mehta
20 Carcinoma of the Esophagus 385Grace J. Kim and Mohan Suntharalingam
Section 4 Gastrointestinal Malignancies 397Section Editor: Christopher G.Willett
21 Gastric Cancer 399Joanna Y. Chin and Theodore S. Hong
22 Pancreatic Cancer 409Manisha Palta, Christopher G.Willett and Brian G. Czito
23 Colon Cancer 429Jennifer Y. Wo
24 Rectal Cancer 438Jennifer Y. Wo
25 Anal Cancer 466Brian G. Czito, Manisha Palta and Christopher G. Willett
Section 5 Genitourinary Malignancies 481Section Editor: Jason A. Efstathiou
26 Bladder Cancer 483Phillip J. Gray,William U. Shipley and Jason A. Efstathiou
27 Prostate Cancer 497Abhishek A. Solanki, Rebecca I. Hartman, Phillip J. Gray, Brent S. Rose, Jonathan J. Paly, Kent W. Mouw and Jason A. Efstathiou
28 Carcinoma of the Upper Urinary Tract 531Anthony L. Zietman, Jonathan J. Paly and Jason A. Efstathiou
29 Testicular Cancer 539Jonathan J. Paly and Jason A. Efstathiou
30 Penile Cancer 549Kent W. Mouw, Anthony L. Zietman and Jason A. Efstathiou
Section 6 Gynecological Malignancies 557Section Editor:William Small Jr.
31 Endometrium 559Ann Klopp and Patricia Eifel
32 Vulva 576Kanokpis Townamchai, Caitlin Newhouse and Akila N. Viswanathan
33 Ovary 597Charles A. Kunos
34 Vagina 618Charles A. Kunos
35 Cervix 631Charles A. Kunos
Section 7 Miscellaneous Sites 673Section Editor:William Small, Jr
36 Cancer of the Skin 675Justin Lee, Elizabeth Barnes, May Tsao and Phillip Devlin
37 Cancer of the Breast 694Jonathan B. Strauss, Monica Morrow and William Small Jr
38 Soft-Tissue Sarcomas 739Jonathan B. Ashman and Kaled M. Alektiar
39 Tumors of the Central Nervous System 757Phillip J. Gray, Jay S. Loeffler and Helen A. Shih
40 The Lymphomas 775Caitlin Costello, Loren K. Mell and Parag Sanghvi
41 Pediatric Tumors 805Shannon M. MacDonald, Torunn I. Yock, Nancy J. Tarbell and Tamara Z. Vern-Gross
Index 845
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