Combined Modality Therapy of Central Nervous System Tumors

by Petrovich, Zbigniew; Brady, Luther W.; Apuzzo, Michael L. J.; Bamberg, Michael; Brady, Luther W.

• ISBN13: 9783540006275
• ISBN10: 3540006273
• Format: Paperback
• Copyright: 2003-09-01
• Publisher: Springer Nature

Summary

The American Cancer Society anticipates that 16,500 patients will be diagnosed with primary malignant tumors of the central nervous system in 2000, with about 200,000 individuals presenting with brain metastases. The advances in the treatment of solid tumors have contributed significantly to the major increase in metastatic cancers to the brain. Of the primary malignant tumors of the brain, more than 50% are high-grade gliomas; the incidence has been increasing among older patients over the past decade. Major developments in new technologies in the treatment of primary brain tumors as well as metastatic disease are covered in depth. Even though management is difficult, advances are being made. This book is a concerted effort to present data regarding basic science research efforts alongside their translation into clinical practice using combined, integrated multimodal programs of treatment. Progress has been made, but innovatice approaches need to be pursued.

Table of Contents

1 Epidemiology of Primary Brain Tumors
S. PRESTON-MARTIN	1	(18)
2 Pathology of CNS Tumors
R.ATKINSON	19	(18)
3 Molecular Biology
R.CLASS	37	(16)
4 Biological Principles of Radiotherapy in the Central Nervous System
J.L. DAIGLE, W.H. MCBRIDE, and H.R. WITHERS	53	(10)
5 Principles of Physics of External Beam Radiotherapy
G. JOZSEF	63	(18)
6 Principles of Physics of Stereotactic Radiosurgery
C. Yu	81	(28)
7 Imaging of Intracranial and Spinal Neoplasms
C.S. ZEE, P. KIM, J.L. GO, and P. CONTI	109	(36)
8 Surgical Management of Pituitary Adenomas
M.D. KRIEGER, A.P. AMAR, and M.H. WEISS	145	(22)
9 Radiotherapy for Pituitary Adenomas
A.-L. GROSU, M. KOCHER, J. VOGES, R.-P. MÜLLER, and M. MOLLS	167	(20)
10 Craniopharyngiomas: Surgical Management
L.T. KHOO, J. FLAGEL, M. LIKER, and M.L. LEVY	187	(28)
11 Radiation Therapy for Craniopharyngioma
M. SELCH	215	(16)
12 Management of Vestibular Schwannomas
S. GHOSH and S. GIANNOTTA	231	(20)
13 Surgical Therapy and Problems in the Treatment of Meningioma
B. GEORGE	251	(14)
14 Radiotherapy for Meningioma
Z. PETROVICH, G. JOZSEF, C.-S. ZEE, and C. YU	265	(14)
15 Management of Low-grade Gliomas: A Surgical Perspective
L.T. KHOO and M.L.J. Aguzzo	279	(38)
16 Radiotherapy in the Management of Low-grade Gliomas
R.D. KORTMANN, B. JEREMIC, and M. BAMBERG	317	(10)
17 Surgical Therapy and Problems in the Treatment of Malignant Gliomas
M. SALCMAN	327	(18)
18 Radiation Therapy Principles for High-Grade Gliomas
C.T. MIYAMOTO	345	(20)
19 The Role of Stereotactic Radiosurgery in the Management of Primary Brain Tumors
D. HUANG, J. CHEN, C. Th, and Z. PETROVICH	365	(22)
20 Frameless Stereotactic Radiosurgery
S.D. CHANG, M.J. MURPHY, D.P. MARTIN, and J.R. ADLER, JR.	387	(10)
21 Treatment of Brain Metastasis
Z. PETROVICH, C. YU, and M.L.J. APUZZO	397	(16)
22 Management of Skull Base Tumors
J.D. DAY and R.A. FREIDMAN	413	(16)
23 Treatment of CNS Lymphomas
S.C. FORMENTI and A. BETTINI	429	(8)
24 Chemotherapy in Adult CNS Tumors
S. O'DAY and B. DYKES	437	(12)
25 Immunotherapy for Primary Brain Tumors
J.E. LAHANIATIS and L.W. BRADY	449	(4)
26 Prospects for Gene Therapy for Brain Tumors
V.C.-K. TSE and G. HARSH	453	(12)
27 Radiation Therapy in the Management of Pediatric Brain Tumors
R.S. LAVEY	465	(14)
28 Surgical Management of Pediatric Patients with CNS Tumors
M.D. KRIEGER, J.G. McCOMB, and M.LEVY	479	(12)
29 Chemotherapy in Pediatric Patients
D.J. HYDER	491	(12)
30 Surgery for Primary and Metastatic Tumors of the Spine
A.T. PARSA, B.D. BIRCH, M.G. KAISER, and P. MCCORMICK	503	(44)
31 Radiotherapy of Tumors of the Spine
Z. PETROVICH,M. LIKER,and G. JOZSEF	547	(16)
32 Management of Rare Central Nervous System Tumors
G. HSU and R. SAWAYA	563	(32)
33 Toxicity of Therapy and Quality of Life in Patients Treated for CNS Tumors
S.C. FORMENTI and Z. PETROVICH	595	(12)
34 Complexity of Nursing in Patients Undergoing Treatment for CNS Tumors
E.M. THOMSON	607	(18)
Subject Index	625	(12)
List of Contributors	637