Comprehensive Textbook of Genitourinary Oncology

by Vogelzang, Nicholas J., M.D.; Shipley, William U., M.D.; Scardino, Peter T.; Coffey, Donald S.

• ISBN13: 9780683306453
• ISBN10: 0683306456
• Edition: 2nd
• Format: Hardcover
• Copyright: 2000-01-01
• Publisher: Lippincott Williams & Wilkins

Summary

Thoroughly revised for its Third Edition, this volume is the most comprehensive, multidisciplinary text on genitourinary cancers. This edition has two new editors Frans M.J. Debruyne and W. Marston Linehan and more than 50% new contributors. Seventeen new chapters cover familial prostate cancer, biology of bone metastases, molecular pathology and biologic determinants, PSA and related kallikreins, needle biopsy, laparoscopic surgical procedures, 3D conformal radiotherapy, hormones and radiotherapy, integration of chemotherapy and other modalities, quality of life after treatment of localized prostate cancer, management of rising PSA after local therapy, the role of surgery in advanced bladder cancer, post-chemotherapy node dissections and resection of metastatic disease, and stem cell transplantation.

Table of Contents

Contributing Authors	xv
Preface	xxix
Preface to the First Edition	xxxi
Acknowledgments	xxxiii
PART I. OVERVIEW OF GENITOURINARY ONCOLOGY
Measuring Genitourinary Cancer Therapy Outcome
Reviewing the Genitourinary Oncology Literature	1	(7)
Malcolm J. Moore
Sue-Anne McLachlan
Principles of Sample Size Computation	8	(8)
Brent A. Blumenstein
Analyzing Health-Related Quality of Life	16	(6)
Mark S. Litwin
Quantitative Approaches to Diagnostic Testing and Decision Making in Genitourinary Oncology	22	(11)
Michael W. Kattan
J. Robert Beck
Brian J. Miles
Supporting the Cancer Patient
Cancer Patient Support and Advocacy	33	(6)
Eugene P. Schonfeld
Charlotte Omohundro
Pain Control in Genitourinary Malignancies	39	(4)
Stuart A. Grossman
The Role of the Social Worker	43	(6)
Janet R. Aminoff
Oncology Nursing Practice	49	(7)
Diana L. Karius
Sheila M. O'Brien
Mary C. Dumas
Hospice Care	56	(4)
Balfour M. Mount
Anemia and Transfusions	60	(5)
Beverly W. Baron
Joseph M. Baron
PART II. PEDIATRIC CANCERS
Wilms' Tumor	65	(8)
Judith Ann Wilimas
Carol A. Greenwald
Bhaskar N. Rao
Neuroblastoma: Natural History and Current Therapeutic Approaches	73	(10)
J. Robert Cassady
John J. Hutter, Jr.
Luke J. Whitesell
Management of Pediatric Genitourinary Rhabdomyosarcoma	83	(8)
John C. Breneman
Sarah S. Donaldson
Eugene S. Wiener
K. Scott Baker
Testicular, Sacrococcygeal, and Other Tumors	91	(10)
Jeffrey S. Palmer
Morris Kletzel
Gary D. Steinberg
William E. Kaplan
PART III. KIDNEY CANCERS
Epidemiology of Renal Cell Carcinoma	101	(10)
Wong-Ho Chow
Susan S. Devesa
Joseph F. Fraumeni, Jr.
Clinical Signs and Symptoms of Renal Cell Carcinoma	111	(5)
W. Scott McDougal
Marc B. Garnick
Molecular Genetics of Renal Cell Carcinoma	116	(13)
McClellan M. Walther
Erik G. Enquist
Scott B. Jennings
James R. Gnarra
Berton Zbar
W. Marston Linehan
Monoclonal Antibodies in the Diagnosis and Treatment of Renal Cancer	129	(7)
Neil H. Bander
Classification of Renal Cancer: Correlation of Morphology and Cytogenetics	136	(7)
Stephan F. Storkel
Radiologic Imaging of Renal Cell Carcinoma: Its Role in Diagnosis, Staging, and Management	143	(136)
Richard A. Leder
Philip J. Walther
Surgical Management of Localized Renal Cell Carcinoma
Radical Nephrectomy for Localized Renal Cell Carcinoma	166	(10)
Joel W. Slaton
David A. Swanson
Nephron-Sparing Surgery for Renal Cell Carcinoma	176	(7)
Andrew C. Novick
Surgical Treatment of Locally Advanced Renal Cell Carcinoma	183	(18)
Joel B. Nelson
Fray F. Marshall
Lymph Node Dissection in the Treatment of Renal Cell Carcinoma	201	(6)
Miguel Srougi
Management of Metastatic Renal Cell Carcinoma
Treatment of Metastatic Renal Cell Cancer with High-Dose Interleukin-2	207	(11)
Jared A. Gollob
Michael B. Atkins
Low-Dose Interleukin-2	218	(16)
Ronald M. Bukowski
Janice P. Dutcher
Cellular and Gene Therapy	234	(14)
Barbara J. Gitlitz
Arie S. Belldegrun
Robert A. Figlin
Chemotherapy, Hormonal Therapy, and Interferons	248	(11)
Christopher P.G. Tretter
Marc S. Ernstoff
Surgical Resection	259	(17)
James M. Kozlowski
Roles of Radiation Therapy and Surgical Resection in the Management of Osseous Metastases from Renal Cell Carcinoma	276	(3)
Ira J. Spiro
Dempsey S. Springfield
PART IV. TRANSITIONAL CELL CARCINOMAS OF THE URINARY TRACT
Clinical Signs and Symptoms of Bladder Cancer	279	(3)
Niall M. Heney
Epidemiology of Bladder Cancer	282	(7)
Edward Schatte
Jennifer Gruenenfelder
Yves Fradet
Brian J. Miles
Biochemical and Molecular Bladder Cancer Carcinogenesis	289	(9)
Santhanam Swaminathan
Catherine A. Reznikoff
Molecular Biology of Bladder Cancer	298	(12)
Isabel D.C. Markl
Carol E. Salem
Peter A. Jones
Pathology of Carcinomas of the Urinary Bladder	310	(12)
Robert H. Young
Cytology of Bladder Cancer	322	(11)
George P. Hemstreet III
Rebecca B. Bonner
Robert E. Hurst
Jian Yu Rao
Screening, Early Detection, and Prevention of Bladder Cancer	333	(10)
Ichabod S. Jung
Edward M. Messing
Staging of Bladder Cancer	343	(13)
Michael J. Droller
Mary K. Gospodarowicz
Imaging for Transitional Cell Carcinomas	356	(69)
Robert A. Badalament
Paul R. Ryan
Duke K. Bahn
Management of Upper Tract Transitional Cell Carcinomas
Endoscopic Management	367	(9)
Jeffry L. Huffman
Surgical Management	376	(8)
Scott D. Dudak
Mark S. Soloway
Endre Z. Neulander
Management of Superficial Ta/T1/TIS Bladder Cancer
Natural History and Surgical Management	384	(10)
Jeffrey M. Holzbeierlein
Joseph A. Smith, Jr.
Intravesical Chemotherapy	394	(14)
J. Alfred Witjes
Frans M. J. Debruyne
Bacille Calmette-Guerin Immunotherapy	408	(9)
M'Liss A. Hudson
Adam J. Gerber
Timothy L. Ratliff
Alternative Immunotherapies for Superficial Bladder Cancer	417	(8)
Donald L. Lamm
Radical Cystectomy for Bladder Cancer	425	(48)
Seth P. Lerner
Donald G. Skinner
Urinary Diversions and Reconstructions
Introduction and Standards	448	(6)
Rodney J. Taylor
Martin T. Grune
Continent Cutaneous Urinary Diversion: The Indiana Pouch	454	(5)
Randall G. Rowland
Orthotopic Bladder Substitution	459	(14)
William H. Turner
Urs E. Studer
Adjuvant and Neoadjuvant Chemotherapy for Invasive Urothelial Carcinoma	473	(40)
John A. McCaffrey
Dean F. Bajorin
Bladder-Preserving Treatments
Role of Transurethral Surgery Alone and with Combined Modality Therapy	483	(4)
Reginald R. Hall
Radiation Therapy for Organ Conservation for Invasive Bladder Carcinoma	487	(9)
Mary K. Gospodarowicz
John P. Blandy
Chemotherapy and Conservative Surgery	496	(9)
Cora N. Sternberg
Vito Pansadoro
Tri-Modality Therapy of Invasive Bladder Cancer with Selective Organ Sparing	505	(8)
Donald S. Kaufman
William U. Shipley
Chemotherapy for Metastatic Disease	513	(12)
Walter M. Stadler
Bruce J. Roth
PART V. PROSTATE CANCER
Clinical Symptoms and Signs of Prostate Cancer	525	(8)
Edward D. Kim
John T. Grayhack
Epidemiology of Prostate Cancer	533	(12)
Otis W. Brawley
Edward Giovannucci
Barnett S. Kramer
Molecular Genetics of Prostate Cancer	545	(8)
William B. Isaacs
Donald S. Coffey
Molecular Biology of Prostate Cancer	553	(12)
Timothy C. Thompson
Terry L. Timme
Chris H. Bangma
Yasutomo Nasu
Gerald W. Hull
Simon J. Hall
Alan M.F. Stapleton
The Androgen Receptor and the Physiology and Endocrinology of the Prostate	565	(60)
Eric J. Small
Gail S. Prins
Mary-Ellen Taplin
Anatomy and Pathology of Prostate Cancer
Anatomy of the Prostate and the Pathology of Prostate Cancer	587	(17)
Thomas M. Wheeler
Prostatic Intraepithelial Neoplasia	604	(8)
David G. Bostwick
Prostatic Prognostic Factors	612	(9)
Gary J. Miller
Neuroendocrine Differentiation in Prostate Cancer	621	(4)
P. Anthony di Sant'Agnese
Prevention of Prostate Cancer	625	(48)
Albert C. Leung
Dov Kadmon
William R. Fair
Prostate-Specific Antigen
Value of Molecular Forms of Prostate-Specific Antigen and Related Kallikrein, hK2, in Diagnosis and Staging of Prostate Cancer	638	(12)
Hans Lilja
Timo P. Piironen
Harry G. Rittenhouse
Stephen D. Mikolajczyk
Kevin M. Slawin
Use of Prostate-Specific Antigen Density and Velocity	650	(4)
Alan W. Partin
H. Ballentine Carter
Screening for Prostate Cancer	654	(19)
Darrel E. Drachenberg
Michael K. Brawer
Staging Systems for Prostate Cancer	673	(7)
James E. Montie
Emerging Prognostic Factors for Outcome Prediction in Clinically Localized Prostate Cancer: Prostate-Specific Antigen Level, Race, Molecular Markers, and Neural Networks	680	(21)
Anthony V.D'Amico
Judd W. Moul
Michael W. Kattan
Imaging in Prostate Cancer	701	(176)
Perinchery Narayan
Kyle K. Yu
Manoj Patel
Hedvig Hricak
Treatment of Early Stage Prostate Cancer
Expectant Management	715	(7)
Peter C. Albertsen
Radical Prostatectomy for Clinical Stage T1 and T2 Prostate Cancer	722	(17)
James A. Eastham
Peter T. Scardino
External-Beam Radiation Therapy for Stage T1 and T2 Prostate Cancer	739	(15)
Deborah A. Kuban
Paul F. Schellhammer
Anas M. El-Mahdi
Brachytherapy	754	(7)
John C. Blasko
Timothy P. Mate
Management Options for Patients with Lymph Node Metastases from Prostate Cancer	761	(13)
Colleen A. Lawton
Gary D. Steinberg
Treatment Options for Locally Advanced Prostate Cancer
Role of Radiation Therapy in the Management of Stage T3 and T4 Prostate Cancer: Rationale, Technique, and Results	774	(8)
W. Robert Lee
Gerald E. Hanks
Timothy E. Schultheiss
Hormonal Therapy Combined with Radiation or Surgery in Treatment of Locally Advanced Nonmetastatic Prostate Cancer	782	(7)
Eric M. Horwitz
Gerald E. Hanks
Primary Surgery for Clinical Stage T3 Adenocarcinoma of the Prostate	789	(10)
Seth E. Lerner
Michael L. Blute
Angelo J. Iocca
Horst Zincke
Primary Hormonal Therapy for Locally Advanced Prostate Cancer	799	(5)
Matthew R. Smith
Marc B. Garnick
Treatment of Locally Recurrent Prostate Cancer
Salvage and Adjuvant Radiation after Radical Prostatectomy	804	(9)
Anthony L. Zietman
Salvage Radical Prostatectomy for Local Recurrence of Prostate Cancer after Radiation Therapy	813	(11)
Brian J. Miles
James R. Herman
Robert E. Reiter
Peter T. Scardino
Initial Management of Metastatic Prostate Cancer
Androgen Blockade: Monotherapy and Quality-of-Life Issues	824	(18)
David G. McLeod
Nicholas J. Vogelzang
Combined Androgen Blockade: Current Controversies. Intermittent/Early versus Late	842	(13)
Keith J.O'Reilly
E. David Crawford
J. Brantley Thrasher
Management of Hormone-Refractory Disease
Secondary Hormonal Manipulation	855	(7)
David C. Smith
Nancy A. Dawson
Donald L. Trump
Current Treatment and Investigative Approaches to the Management of Hormone-Refractory Prostate Cancer	862	(8)
Christopher J. Logothetis
Nicholas J. Vogelzang
Role of Radiation Therapy in the Management of Hormone-Refractory Metastatic Prostate Cancer	870	(7)
Vaneerat Ratanatharathorn
Charles W. Scarantino
PART VI. TESTIS CANCER
Clinical Signs and Symptoms	877	(3)
B.J. Kennedy
Epidemiology of Testis Cancer: A Clinical Perspective	880	(11)
R.T.D. Oliver
Molecular Biology of Adult Male Germ Cell Tumors	891	(6)
R.S.K. Chaganti
Jane Houldsworth
George J. Bosl
Carcinoma in Situ of the Testis--A Precursor of Testicular Germ Cell Cancer: Biological and Clinical Aspects	897	(12)
Ewa Rajpert-De Meyts
Aleksander Giwercman
Niels E. Skakkebaek
Anatomy and Pathology of Testis Cancer	909	(18)
Fathollah K. Mostofi
Isabell A. Sesterhenn
Charles J. Davis, Jr.
Serum Tumor Markers and Their Role in Monitoring Germ Cell Cancers of the Testis	927	(12)
Mark Bower
Gordon J.S. Rustin
Staging and Imaging of Testis Cancer	939	(36)
Graeme S. Steele
Philip W. Kantoff
Jerome P. Richie
Surgical Management
Radical Orchiectomy	950	(5)
Judd W. Moul
Robert C. Dean
David G. McLeod
Retroperitoneal Lymph Node Dissection	955	(6)
Richard S. Foster
John P. Donohue
Resection of Metastatic Disease	961	(14)
W. Bedford Waters
Ryan Manecke
Observation and Expectant Management for Low-Stage Seminoma and Nonseminoma	975	(6)
Gedske Daugaard
Mikael Roerth
Chemotherapy for Stage I and II Testis Cancer	981	(51)
Robert J. Amato
Radiation Therapy
Treatment of Patients with Stage I Seminoma of the Testis	987	(11)
Gillian M. Thomas
Seminoma: Management of Stage II Disease, Posttherapy Residual Masses, and Other Special Considerations	998	(12)
Stephen R. Smalley
Peter J. Van Veldhuizen
Chemotherapeutic Management of Metastatic Germ Cell Testis Cancer
Overview of Initial Therapy for Metastatic Seminoma and Nonseminoma	1010	(7)
Scott B. Saxman
Patrick J. Loehrer
Risk-Adapted Therapy/Good-Risk Patients	1017	(7)
Dean F. Bajorin
Risk-Adapted Therapy/Poor-Risk Patients	1024	(8)
G.M. Mead
Extragonadal Germ Cell Tumors	1032	(5)
Jean-Pierre Droz
Alan Horwich
Relapsed Testis Cancer: Treatment of Recurrent Germ Cell Tumors	1037	(8)
Craig R. Nichols
Late Toxicity after Chemotherapy of Germ Cell Testis Cancer	1045	(28)
Sophie D. Fossa
Nina Aass
Derek Raghavan
Nicholas J. Vogelzang
PART VII. PENILE CANCER
Penile Cancer
Overview	1051	(6)
Walter M. Stadler
Nicholas J. Vogelzang
Christine M. Elwell
William G. Jones
Surgical Management of Penile Cancer	1057	(8)
Gerald L. Andriole
David C. Miller
John W. Colberg
William J. Catalona
Radiation Therapy for Penile Cancer	1065	(5)
Christine M. Elwell
William G. Jones
Chemotherapy for Penile Cancer	1070	(3)
Walter M. Stadler
PART VIII. OTHER UROLOGIC MALIGNANCIES
Adrenal Neoplasms	1073	(29)
Ronald M. Bukowski
Eric A. Klein
Genitourinary Sarcomas and Carcinosarcomas in Adults	1102	(18)
Igor Frank
Satoru Takahashi
Taiji Tsukamoto
Michael M. Lieber
Malignant Lymphoma of the Genitourinary Tract	1120	(13)
A. Dimitrios Colevas
Philip W. Kantoff
William C. DeWolf
George P. Canellos
Urethral Tumors	1133	(8)
Perry W. Grigsby
Harry W. Herr
Miscellaneous Tumors of the Genitourinary Tract	1141	(18)
Javid Javidan
Howard J. Korman
Mahul B. Amin
James O. Peabody
Index	1159