Concepts of Genetics

by Klug, William S.; Cummings, Michael R.; Spencer, Charlotte A.; Palladino, Michael A.

• ISBN13: 9780321524041
• ISBN10: 0321524047
• Edition: 9th
• Format: Hardcover
• Copyright: 2008-02-06
• Publisher: Benjamin Cummings

Summary

Known for its focus on concepts and problem-solving, this best-selling book has been extensively updated with new coverage of genomics, bioinformatics, proteomics and more.Concepts of Genetics, 9/eis written in a clear and accessible style for readers. Introduction to Genetics, Mitosis and Meiosis, Mendelian Genetics, Extensions of Mendelian Ratios, Chromosome Mapping in Eukaryotes, Genetic Analysis and Mapping in Bacteria and Bacteriophages, Sex Determination and Sex Chromosomes, Chromosome Mutations: Variation in Chromosome Number and Arrangement, Extranuclear Inheritance, DNA Structure and Analysis, DNA Replication and Recombination, DNA Organization in Chromosomes, Recombinant DNATechnology and Gene Cloning, The Genetic Code and Transcription, Translation and Proteins, Gene Mutation and DNA Repair, Regulation of Gene Expression in Prokaryotes, Regulation of Gene Expression in Eukaryotes, Developmental Genetics of Model Organisms, Cancer and Regulation of the Cell Cycle, Genomics, Proteomics, and Bioinformatics, Genome Dynamics: Transposons, Immunogenetics, and Eukaryotic Viruses, Genomic Analysis--Dissection of Gene Function, Applications and Ethics of Genetic Engineering and Biotechnology, Quantitative Genetics and Multifactorial Traits, Genetics and Behavior, Population Genetics, Evolutionary Genetics, Conservation Genetics.Intended for those interested in learning the basics of genetics

Author Biography

William S. Klug is currently Professor of Biology at the College of New Jersey (formerly Trenton State College) in Ewing, New Jersey. He served as chair of the Biology Department for 17 years, a position to which he was first elected in 1974. He received his B.A. degree in Biology from Wabash College in Crawfordsville, Indiana, and his Ph.D. from Northwestern University in Evanston, Illinois. Prior to coming to the College of New Jersey, he was on the faculty of Wabash College as an Assistant Professor. His research interests have involved ultrastructural and molecular genetic studies of oogenesis in Drosophila. He has taught the genetics course as well as the senior capstone seminar course in human and molecular genetics to undergraduate biology majors for each of the last 35 years. In 2002, he was the recipient of the initial teaching award given at the College of New Jersey granted to the faculty member who most challenges students to achieve high standards. He also received the 2004 Outstanding Professor Award from the Sigma Pi International, and in the same year, he was nominated as the Educator of the Year, an award given by the Research and Development Council of New Jersey.

 

Michael R. Cummings is currently Research Professor in the Department of Biological, Chemical and Physical Sciences at Illinois Institute of Technology, Chicago, Illinois. For more than 25 years, he was a faculty member in the Department of Biological Sciences and in the Department of Molecular Genetics at the University of Illinois at Chicago. He has also served on the faculties of Northwestern University and Florida State University. He received his B.A. from St. Mary's College in Winona, Minnesota, and his M.S. and Ph.D. from Northwestern University in Evanston, Illinois. In addition to Concepts of Genetics and its companion volumes, he has also written textbooks in human genetics and general biology for nonmajors. His research interests center on the molecular organization and physical mapping of the heterochromatic regions of human acrocentric chromosomes. At the undergraduate level, he teaches courses in Mendelian and molecular genetics, human genetics, and general biology, and has received numerous awards for teaching excellence given by university faculty, student organizations and graduating seniors.

 

Charlotte A. Spencer is currently an Associate Professor in the Department of Oncology at the University of Alberta in Edmonton, Alberta, Canada. She has also served as a faculty member in the Department of Biochemistry at the University of Alberta. She received her B.Sc. in Microbiology from the University of British Columbia and he Ph.D. in Genetics from the University of Alberta, followed by postdoctoral training at the Fred Hutchinson Cancer Research Center in Seattle, Washington. Her research interests involve the regulation of RNA polymerase II transcription in cancer cells, cells infected with DNA viruses and cells transversing the mitotic phase of the cell cycle. She has taught courses in Biochemistry, Genetics, Molecular Biology and Oncology, at both undergraduate and graduate levels. She has contributed Genetics, Technology and Society essays for several editions of Concepts of Genetics as well as Essentials of Genetics. In addition, she has written booklets in the Exploring Biology series, which are aimed at the undergraduate nonmajors level.

 

Michael A. Palladino is Associate Professor in the Department of Biology at Monmouth University in West Long Branch, New Jersey. He received his B.S. degree in Biology from Trenton State College (now known as The College of New Jersey) and his Ph.D. in Anatomy and Cell Biology from the University of Virginia. He directs an active laboratory of undergraduate student researchers studying molecular mechanisms involved in innate immunity of mammalian male reproductive organs and genes involved in oxygen homeostasis and ischemic injury of the testis. He has taught a wide range of courses for both majors and nonmajors and currently teaches genetics, biotechnology, endocrinology, and laboratory in cell and molecular biology. He has received several awards for research and teaching, including the New Investigator Award of the American Society of Andrology, the 2005 Distinguished Teacher Award from Monmouth University, and the 2005 Caring Heart Award from the New Jersey Association for Biomedical Research. He is co-author of the undergraduate textbook Introduction to Biotechnology, Series Editor for the Benjamin Cummings Special Topics in Biology booklet series, and author of the first booklet in the series, Understanding the Human Genome Project. 

 

Table of Contents

Introduction to Genetics

Mitosis and Meiosis

Mendelian Genetics

Extensions of Mendelian Ratios

Chromosome Mapping in Eukaryotes

Genetic Analysis and Mapping in Bacteria and Bacteriophages

Sex Determination and Sex Chromosomes

Chromosome Mutations: Variation in Chromosome Number and Arrangement

Extranuclear Inheritance

DNA Structure and Analysis

DNA Replication and Recombination

DNA Organization in Chromosomes

Recombinant DNATechnology and Gene Cloning

The Genetic Code and Transcription

Translation and Proteins

Gene Mutation and DNA Repair

Regulation of Gene Expression in Prokaryotes

Regulation of Gene Expression in Eukaryotes

Developmental Genetics of Model Organisms

Cancer and Regulation of the Cell Cycle

Genomics, Proteomics, and Bioinformatics

Genome Dynamics: Transposons, Immunogenetics, and Eukaryotic

Viruses

Genomic Analysis--Dissection of Gene Function

Applications and Ethics of Genetic Engineering and Biotechnology

Quantitative Genetics and Multifactorial Traits

Genetics and Behavior

Population Genetics

Evolutionary Genetics

Conservation Genetics

Glossary

Answers To Selected Problems

Credits

Index

Table of Contents provided by Publisher. All Rights Reserved.