Endocrinology

by Shlomo, Melmed, M.D.; Conn, P. Michael; Melmed, Shlomo

• ISBN13: 9781588294272
• ISBN10: 1588294277
• Edition: 2nd
• Format: Hardcover
• Copyright: 2005-07-15
• Publisher: Humana Pr Inc

Summary

Maintaining the original goal of the first edition to integrate the basic science of endocrinology with its physiological and clinical principles, this new edition succinctly summarizes in 450 pages the latest findings on hormone secretion and hormone action, as well as all the most recent insights into the physiology and pathophysiology of hormonal disorders. Coverage extends across the entire spectrum of endocrinology-from mammalian cells, plants, and insects to animal models and human diseases-with much increased coverage of diabetes and metabolism. Highlights include cutting-edge discussions of appetite disorders, obesity, reproductive failure, control of thyroid function, hormone action in man and the lower species, and the mechanisms subserving hormone secretion.

Table of Contents

Preface	vii
Contributors	ix
Value Added eBook	xi
Part I. Introduction
Introduction to Endocrinology	3	(6)
P. Michael Conn
Part II. Hormone Secretion and Action
Receptors: Molecular Mediators of Hormone Action	9	(26)
Kelly E. Mayo
Second-Messenger Systems and Signal Transduction Mechanisms	35	(14)
Eliot R. Spindel
Steroid Hormones	49	(18)
Derek Henley
Jonathan Lindzey
Kenneth S. Korach
Plasma Membrane Receptors for Steroid Hormones in Cell Signaling and Nuclear Function	67	(18)
Richard J. Pietras
Clara M. Szego
Growth Factors	85	(8)
Derek LeRoith
William L. Lowe Jr.
Prostaglandins and Leukotrienes: Locally Acting Agents	93	(20)
John A. McCracken
The Neuroendocrine-Immune Interface	113	(14)
Michael S. Harbuz
Stafford L. Lightman
Part III. Insects/Plants/Comparative
Insect Hormones	127	(10)
Lawrence I. Gilbert
Phytohormones and Signal Transduction Pathways in Plants	137	(12)
William Teale
Ivan Paponov
Olaf Tietz
Klaus Palme
Comparative Endocrinology	149	(24)
Fredrick Stormshak
Part IV. Hypothalamic---Pituitary
Hypothalamic Hormones: GnRH, TRH, GHRH, SRIF, CRH, and Dopamine	173	(24)
Constantine A. Stratakis
George P. Chrousos
Anterior Pituitary Hormones	197	(14)
Ilan Shimon
Shlomo Melmed
Posterior Pituitary Hormones	211	(22)
Daniel G. Bichet
Endocrine Disease: Value for Understanding Hormonal Actions	233	(22)
Anthony P. Heaney
Glenn D. Braunstein
The Pineal Hormone (Melatonin)	255	(12)
Irina V. Zhdanova
Richard J. Wurtman
Thyroid Hormones (T4, T3)	267	(16)
Takahiko Kogai
Gregory A. Brent
Calcium-Regulating Hormones: Vitamin D and Parathyroid Hormone	283	(18)
Geoffrey N. Hendy
Oncogenes and Tumor Suppressor Genes in Tumorigenesis of the Endocrine System	301	(10)
Anthony P. Heaney
Shlomo Melmed
Insulin Secretion and Action	311	(10)
Run Yu
Hongxiang Hui
Shlomo Melmed
Cardiovascular Hormones	321	(16)
Willis K. Samson
Meghan M. Taylor
Adrenal Medulla (Catecholamines and Peptides)	337	(16)
William J. Raum
Hormones of the Kidney	353	(14)
Masashi Mukoyama
Kazuwa Nakao
Reproduction and Fertility	367	(8)
Neena B. Schwartz
Endocrinology of Fat, Metabolism, and Appetite	375	(16)
Rachel L. Batterham
Michael A. Cowley
Endocrinology of the Ovary	391	(14)
Denis Magoffin
Ashim Kumar
Bulent Yildiz
Ricardo Azziz
The Testis	405	(14)
Amiya Sinha Hikim
Ronald S. Swerdloff
Christina Wang
Endocrinology of Aging	419	(10)
Steven W. J. Lamberts
Index	429

Excerpts

"For this new edition of Conn & Melmed's Endocrinology: Basic and Clinical Principles, a panel of scientists and clinicians has completely rewritten every chapter to reflect the latest advances in our understanding of the endocrine system. Maintaining the original goal of the first edition to integrate the basic science of endocrinology with its physiological and clinical principles, the authors have succinctly summarized in 500 pages the latest findings on hormone secretion and hormone action, as well as all the most recent insights into the physiology and pathophysiology of hormonal disorders." "Concise yet comprehensive, Endocrinology: Basic and Clinical Principles, Second Edition offers students, clinicians, and scientists access to the entire spectrum of endocrinological knowledge, authoritatively illuminating the basic scientific principles underlying every aspect of hormone secretion and action, and leading the reader towards a full understanding of the pathogenesis and management of human endocrine disease."--BOOK JACKET.