Foreword | p. vii |
Preface | p. ix |
User's Guide | p. xiii |
Acknowledgements | p. xvii |
Reviewers | p. xix |
Energy: the Basis of Human Movement | p. 1 |
Exercise Bioenergetics: Energy Developed | |
Introduction to Exercise Physiology | p. 2 |
A Future Perspective on Exercise | p. 2 |
What is Exercise Physiology? | p. 5 |
The Academic Setting | p. 5 |
A Unified Vision of Exercise Science as a Discipline | p. 6 |
Exercise Physiology and the Disablement Model | p. 8 |
Movement, Physical Activity, and Exercise | p. 11 |
Exercise and Physical Activity as Stressors | p. 15 |
A Brief History of Exercise in Medicine | p. 17 |
The "Laws of Health" from Ancient Medicine to the 19th Century | p. 17 |
19th Century Foundation and The Rise of Exercise Physiology | p. 18 |
Nutrients for Physical Activity | p. 21 |
Nutrients: Building Blocks of Energy | p. 22 |
Carbohydrates | p. 22 |
Monosaccharides | p. 23 |
Disaccharides | p. 23 |
Polysaccharides | p. 23 |
Digestion and Absorption of Carbohydrates | p. 25 |
The Role of Carbohydrates in the Body | p. 25 |
Fats | p. 27 |
Triglycerides and Fatty Acids | p. 27 |
Phospholipids | p. 30 |
Lipoproteins | p. 30 |
Glycolipids | p. 31 |
Sterols | p. 31 |
Digestion and Absorption of Fats | p. 31 |
The Role of Fats in the Body | p. 31 |
Proteins | p. 32 |
Digestion and Absorption of Proteins | p. 33 |
The Role of Proteins in the Body | p. 34 |
Vitamins | p. 34 |
Fat-Soluble Vitamins | p. 36 |
Water-Soluble Vitamins | p. 37 |
Minerals | p. 38 |
The Major Minerals | p. 38 |
The Trace Minerals | p. 40 |
Water | p. 40 |
Dietary Guidelines | p. 43 |
Food Guide Pyramid | p. 43 |
Vegetarianism | p. 45 |
Energy Sources and Production | p. 49 |
Energy Defined | p. 49 |
Energy Forms | p. 51 |
Biochemical Reactions are Linked | p. 51 |
Anabolism and Catabolism | p. 52 |
Phosphate Energy | p. 53 |
ATP-The Energy Exchange Currency | p. 53 |
Energy Flows from Creatine Phosphate to ADP | p. 54 |
Oxidation-Reduction Reactions | p. 55 |
Sarcoplasmic Catabolism | p. 56 |
The Energy Continuum | p. 56 |
Immediate Energy | p. 58 |
Short-term Energy | p. 60 |
Lypolysis | p. 64 |
Mitochondrial Catabolism | p. 66 |
[beta] Oxidation | p. 68 |
Krebs Cycle | p. 68 |
Electron Transport Chain | p. 71 |
Tallying ATP | p. 73 |
Metabolic Transitions During Exercise | p. 75 |
Rest-to-Exercise Transitions | p. 76 |
Energy Accessibility | p. 76 |
Energy Systems Stressed by Exercise | p. 77 |
Response to Exercise Energy Demands: Hormonal Regulation | p. 78 |
Results of an Exercise-Induced Rise in Metabolism | p. 86 |
Maintaining Energy Supply During Exercise | p. 89 |
Exercise Intensity and Fuel Selection | p. 91 |
Exercise Duration and Fuel Supply | p. 92 |
Recovery From Exercise: Resynthesis of Fuels | p. 94 |
Regeneration of ATP and PC | p. 94 |
Reformation of Glucose | p. 94 |
Synthesis of Glycogen | p. 95 |
Synthesis of Fatty Acids and Triglycerides | p. 96 |
Ergometry and Calorimetry: The Measurement of Work and Energy | p. 98 |
Ergometry: The Measurement of Work | p. 98 |
Units of Measurement | p. 100 |
Common Ergometers | p. 104 |
Calorimetry: The Measurement of Energy | p. 107 |
Direct Calorimetry | p. 107 |
Indirect Calorimetry | p. 109 |
Measuring Vo[subscript 2] and Vco[subscript 2] by Open-Circuit Spirometry | p. 111 |
Standardizing Gas Volumes | p. 111 |
Energy Expenditure | p. 114 |
Expressing Vo[subscript 2] | p. 114 |
Respiratory Exchange Ratio | p. 115 |
Basal and Resting Metabolic Rate | p. 116 |
Efficiency and Economy | p. 116 |
Efficiency | p. 117 |
Economy | p. 119 |
Clinical Applications | p. 120 |
Energy Cost of Physical Activity | p. 120 |
Relationship Between Heart Rate and VO[subscript 2] | p. 123 |
Estimating Submaximal Vo[subscript 2]: The Metabolic Equations | p. 124 |
Heart and Lungs: Energy Delivered | |
Respiratory Exercise Physiology | p. 127 |
Exchange of Respiratory Gases at the Alveolar-Capillary Interface | p. 128 |
Respiratory Gases Move By Diffusion | p. 129 |
Driving Pressure and Gas Diffusion | p. 129 |
Short Distances Enhance Diffusion | p. 132 |
Diffusivity Determines Rapidity of Diffusion | p. 132 |
Diffusion and Transit Time | p. 133 |
Ventilating the Lungs | p. 134 |
Ventilatory Parameters | p. 134 |
The Ventilatory Pump | p. 137 |
The Respiratory Tree | p. 139 |
Ventilation/Perfusion Matching | p. 141 |
Pulmonary Perfusion | p. 141 |
Physiology of V/Q Matching | p. 143 |
Transport of Oxygen and Carbon Dioxide | p. 145 |
Oxygen Transport | p. 145 |
Carbon Dioxide Transport | p. 149 |
Control of Breathing | p. 151 |
Exercise Ventilation | p. 151 |
Central and Peripheral Roles | p. 153 |
Chemical Control of Respiration | p. 155 |
Cardiovascular Exercise Physiology | p. 161 |
The Heart and Circulation | p. 161 |
Cardiac Structure | p. 162 |
Cardiac Electrical Activity | p. 164 |
Cardiac Cycle | p. 169 |
Arteries, Arterioles, Metarterioles, and Capillaries | p. 173 |
Veins | p. 173 |
Regulation of Peripheral Blood Flow | p. 175 |
Distribution of Blood Flow | p. 175 |
Factors Controlling Muscle Blood Flow | p. 175 |
Determinants of Blood Flow | p. 176 |
Cardiac and Circulatory Dynamics | p. 177 |
Blood Pressure | p. 178 |
Cardiac Output | p. 181 |
Cardiovascular Adjustments to Acute and Chronic Exercise | p. 184 |
Heart Rate | p. 185 |
Cardiac Output and Stroke Volume | p. 188 |
Blood Pressure | p. 191 |
[Delta]a-vO[subscript 2] | p. 193 |
Homothermal Control: Temperature Regulation During Exercise | p. 195 |
Temperature Balance During Exercise | p. 195 |
Heat Exchange by Conduction | p. 197 |
Heat Exchange by Convection | p. 197 |
Heat Exchange by Radiation | p. 198 |
Heat Exchange by Evaporation | p. 198 |
Assessment of Body Temperature | p. 199 |
Integration of Heat Transfer Mechanisms | p. 199 |
Temperature Regulation in Hot Environments | p. 201 |
The Thermal Regulatory Center | p. 201 |
Cardiovascular Adjustments to Heat Exposure | p. 202 |
Acclimatization to Heat | p. 203 |
Heat Disorders | p. 204 |
Assessing Environmental Heat Stress | p. 205 |
Age and Gender Differences in Heat Regulation | p. 207 |
Protection Against Heat Disorders | p. 209 |
Temperature Regulation in Cold Environments | p. 211 |
The Thermal Regulatory Center | p. 211 |
Cardiovascular Adjustments to Cold Exposure | p. 212 |
Acclimatization to the Cold | p. 212 |
Health Risks from Cold Exposure | p. 212 |
Assessing Environmental Cold Stress | p. 212 |
Age and Gender Differences in Cold Tolerance | p. 212 |
Protection Against Cold Exposure | p. 213 |
Muscles: Energy Used | |
Neuroanatomy and Neuromuscular Control of Movement | p. 217 |
Nervous System Organization | p. 218 |
The Neuron | p. 218 |
Parts of the Neuron | p. 219 |
Functions of Neurons | p. 220 |
Action Potentials | p. 220 |
Synaptic Transmission | p. 221 |
Central Nervous System | p. 225 |
The Brain | p. 225 |
The Spinal Cord | p. 229 |
Supporting Cells of the Central Nervous System | p. 233 |
Peripheral Nervous System | p. 233 |
Cranial Nerves | p. 233 |
Spinal Nerves | p. 235 |
Autonomic Nervous System | p. 237 |
Sympathetic Nervous System | p. 237 |
Parasympathetic Nervous System | p. 237 |
Somatic Motor System | p. 239 |
Motor Neurons | p. 239 |
Spinal Control of Motor Units | p. 240 |
Motor Programming | p. 244 |
Feedback and Practice | p. 245 |
Skeletal Muscle Architecture and Contraction | p. 247 |
Skeletal Muscle Structure | p. 247 |
Gross Structure of Muscle | p. 248 |
Muscle Morphology and Architecture | p. 252 |
Muscle Contraction | p. 255 |
Sliding Filament Theory | p. 255 |
Energy for Contraction | p. 255 |
Excitation-Contraction Coupling | p. 256 |
Muscle Fiber Types | p. 258 |
Muscle Biopsy | p. 259 |
Histochemical Classification | p. 259 |
Biochemical Classification | p. 259 |
Molecular Classification | p. 259 |
Physiologic Properties of Fiber Types | p. 261 |
Maximum Tension Generation | p. 262 |
Maximal Velocity of Shortening | p. 263 |
Metabolic and Biochemical Differences | p. 263 |
Structural Differences | p. 263 |
Muscle Fiber Plasticity | p. 264 |
Aerobic Exercise | p. 264 |
Resistance Training | p. 264 |
Age-related Changes | p. 264 |
Immobilization-Induced Changes | p. 266 |
Muscle Mechanics During Activity | p. 270 |
The Motor Unit | p. 270 |
Motor Unit Anatomy and Function | p. 271 |
Fatigue Index | p. 272 |
Motor Unit Recruitment | p. 272 |
Muscle Mechanics | p. 273 |
Length-Tension Curve | p. 275 |
Force-Velocity Relationship | p. 275 |
Muscle Fatigue | p. 276 |
Muscle Strength | p. 277 |
Skeletal Muscle Adaptations to Strength Training | p. 277 |
Measurement of Muscle Strength | p. 278 |
Applied Exercise Physiology | p. 287 |
Physiology of Health, Fitness, and Performance | |
Nutrition and Exercise Performance | p. 288 |
Carbohydrate Intake and Exercise Performance | p. 288 |
High-Carbohydrate Diets | p. 289 |
Carbohydrate Ingestion Prior to Exercise | p. 290 |
Carbohydrate Ingestion During Exercise | p. 291 |
Carbohydrate Ingestion After Exercise | p. 292 |
High-Fat Diets | p. 295 |
High-Protein Diets | p. 296 |
Fad Diets and Weight Loss | p. 297 |
Exercise Performance and Vitamin/Mineral Supplements | p. 300 |
Vitamin Supplements | p. 300 |
Mineral Supplements | p. 301 |
Evaluation of Dietary Supplements | p. 303 |
Exercise Performance and Fluid Intake | p. 306 |
Assessment of Body Composition | p. 310 |
Ideal Body Weight | p. 310 |
Body Fat and Disease Risk | p. 311 |
Body Composition and Athletic Performance | p. 312 |
Methods for the Assessment of Body Composition | p. 313 |
Measures of Circumference | p. 314 |
Body Mass Index (BMI) | p. 315 |
Hydrostatic Weighing | p. 316 |
Air Displacement Plethysmography | p. 318 |
Skinfold Thickness | p. 320 |
Total Body Water Measures | p. 323 |
Total Body Electrical Conductivity (TOBEC) | p. 323 |
Bioelectrical Impedance Analysis (BIA) | p. 323 |
Ultrasound | p. 324 |
Nuclear Magnetic Resonance (NMR) | p. 324 |
Near-Infrared Interactance | p. 326 |
Computed Tomography | p. 326 |
Dual-energy X-ray Absorptiometry (DXA) | p. 326 |
Body Composition Assessment in Children | p. 331 |
Body Mass Index in Children | p. 331 |
Body Composition Measures in Children | p. 332 |
Training for Physical Fitness and Sport | p. 334 |
Principles of Training | p. 334 |
Specificity | p. 335 |
Overload | p. 341 |
Training for Muscular Fitness | p. 344 |
Training for Strength Performance | p. 344 |
Training for Power Performance | p. 347 |
Training for Speed Performance | p. 351 |
Training for Aerobic Endurance | p. 352 |
Exercise Dosage | p. 353 |
Determining Exercise Intensity | p. 354 |
Endurance Training Techniques | p. 358 |
Exercise Performance for Specific Populations | |
Pediatric Exercise Physiology | p. 361 |
Growth, Development and Maturation | p. 361 |
Anthropometric Growth and Development | p. 362 |
Physiological Development | p. 362 |
Evaluating Fitness and Physical Activity in Children | p. 365 |
Fitness Testing of Children | p. 366 |
Clinical Exercise Testing of Children | p. 372 |
Assessing Physical Activity in Children | p. 374 |
Childhood Responses to Physical Activity and Exercise Training | p. 378 |
Exercise Capacities of Children Versus Adults | p. 379 |
Exercise Injuries in Children | p. 379 |
Emotional Distress in Young Athletes | p. 382 |
Behavior Carryover | p. 383 |
Exercise Prescription, Guidelines, and Recommendations for Children | p. 384 |
Geriatric Exercise Physiology | p. 387 |
Aging | p. 387 |
Definition of Aging | p. 388 |
Theories of Aging | p. 389 |
Aging, Physical Inactivity, and Disability | p. 390 |
Aging, Health Status, and Functional Capacity | p. 391 |
Exercise Physiological Changes with Aging | p. 393 |
The Cardiovascular System | p. 394 |
The Pulmonary System | p. 397 |
The Neuromuscular System | p. 397 |
Exercise Training for the Elderly | p. 400 |
Exercise Guidelines for Older Adults | p. 400 |
Female-Specific Issues | p. 405 |
Comparisons Between the Sexes | p. 405 |
Morphological Differences | p. 406 |
Physiological Differences | p. 407 |
Trainability | p. 411 |
Gynecological Considerations | p. 413 |
Menstruation | p. 413 |
Pregnancy | p. 414 |
Lactation | p. 417 |
Menopause | p. 419 |
Nutritional Issues | p. 419 |
Osteoporosis | p. 420 |
Iron Deficiency | p. 421 |
Eating Disorders | p. 421 |
Female Athlete Triad | p. 423 |
Excessive Exercise Disorder | p. 424 |
Special Nutritional Needs for Women | p. 424 |
Exercise Physiology for Clinical Populations | p. 429 |
Clinical Foundations | |
Introduction to Pharmacology and Pathophysiology | p. 430 |
Basic Pharmacology | p. 430 |
Definition of Pharmacology | p. 431 |
Pharmacokinetics and Pharmacodynamics | p. 431 |
Commonly Encountered Medications in Clinical Exercise Programs | p. 436 |
Cardiovascular Medications | p. 436 |
Pulmonary Medications | p. 442 |
Overview of Cardiovascular Pathophysiology | p. 444 |
Signs and Symptoms of Cardiovascular Disease | p. 444 |
Cardiovascular Disorders | p. 447 |
Overview of Pulmonary Pathophysiology | p. 450 |
Chronic Obstructive Pulmonary Diseases | p. 451 |
Restrictive Lung Disease | p. 452 |
Respiratory Acidosis and Alkalosis | p. 453 |
Overview of Metabolic Pathophysiology | p. 455 |
Diabetes Mellitus | p. 455 |
Metabolic Acidosis and Alkalosis | p. 455 |
Disablement and Exercise Prescription | p. 458 |
Conceptualization of Disability | p. 458 |
A Public Health Initiative | p. 458 |
Pathway to Disablement | p. 460 |
Disablement Models | p. 462 |
The Nagi Model of Disablement | p. 462 |
A New Perspective on the Disablement Process Model | p. 464 |
Disability and the Exercise Prescription | p. 466 |
Passive Stimulus-Response Paradigm | p. 466 |
Exercise Prescription Intervention Triad | p. 468 |
Functional Status | p. 471 |
Activity and Dosage | p. 471 |
Clinical Exercise Testing | p. 474 |
Measuring Cardiovascular Endurance | p. 474 |
Ventilatory and Lactate Threshold | p. 475 |
Determining VO[subscript 2max] | p. 475 |
Principles of Exercise Testing | p. 479 |
Sensitivity, Specificity, and Predictive Accuracy of Exercise Testing | p. 480 |
Health Screening and Risk Stratification Prior to Exercise Testing | p. 481 |
Selecting the Graded Exercise Protocol | p. 484 |
Treadmill Protocols | p. 486 |
Leg and Arm Ergometer Protocols | p. 487 |
Field and Submaximal Exercise Testing | p. 488 |
Exercise Electrocardiography | p. 489 |
The 12-Lead Electrocardiogram | p. 489 |
Recognizing Ischemic Responses | p. 496 |
Recognizing Arrhythmias | p. 499 |
The Graded Exercise Test | p. 506 |
Preparation for Testing | p. 506 |
Components of the Graded Exercise Test | p. 509 |
Absolute Indications | p. 509 |
Relative Indications | p. 510 |
Interpreting Results | p. 510 |
Exercise Rehabilitation and Specific Disorders | |
Exercise for Cardiopulmonary Disorders | p. 513 |
Cardiovascular Endurance, Physical Activity, and Health | p. 513 |
The Exercise Prescription | p. 517 |
The Exercise Prescription Intervention Triad | p. 518 |
Exercise Prescription for Cardiovascular Endurance Impairment | p. 518 |
Cardiopulmonary Rehabilitation | p. 519 |
The Exercise Session | p. 523 |
Sequencing | p. 525 |
Environment and Feedback | p. 526 |
Exercise for Obesity and Weight Control | p. 529 |
Problems with Obesity | p. 529 |
The Prevalence of Obesity | p. 530 |
Obesity and Disease Risk | p. 530 |
Exercise, Body Weight, and Health | p. 531 |
Assessment of the Overweight Patient | p. 532 |
Etiology of Obesity | p. 532 |
Genetics and Body Weight | p. 532 |
Energy Intake and Body Fatness | p. 535 |
Diet Composition and Body Composition | p. 536 |
Inactivity and Overweight | p. 537 |
Metabolic Rate and Overweight | p. 538 |
Psychological Aspects of Obesity | p. 539 |
The Psychological Profile of the Obese Person | p. 539 |
Body Image Disparagement | p. 540 |
Emotional Distress and Weight Control | p. 541 |
Barriers to Weight Control | p. 543 |
Effectiveness of Exercise in Weight Control | p. 544 |
Exercise and Metabolism | p. 544 |
Exercise Intensity and Substrate Use | p. 547 |
Exercise and Weight-Loss Success | p. 547 |
The Exercise Prescription | p. 548 |
Relapse Prevention | p. 550 |
Exercise for Oncological and Neuromusculoskeletal Disorders | p. 554 |
Brain and Nerve Disorders | p. 554 |
Stroke | p. 555 |
Multiple Sclerosis | p. 557 |
Muscular Dystrophy | p. 560 |
Epilepsy | p. 562 |
Parkinson Disease | p. 563 |
Alzheimer Disease | p. 563 |
Cancers | p. 566 |
Etiologies, Symptoms, and Prognosis | p. 566 |
Exercise Benefits | p. 568 |
Exercise Prescription | p. 571 |
Bone and Joint Disorders | p. 571 |
Etiologies, Symptoms and Prognosis | p. 572 |
Exercise Benefits | p. 573 |
Exercise Prescription | p. 573 |
Experiences in Work Physiology | p. 577 |
Tests and Measures Used in Exercise Physiology | p. 578 |
Analyzing Your Diet | p. 579 |
Temperature Regulation During Exercise | p. 581 |
Measuring Metabolic Transitions from Rest to Exercise | p. 582 |
Measuring Cycling Efficiency | p. 584 |
Ventilatory Threshold | p. 585 |
Isometric Contractions and Cardiovascular Function | p. 586 |
Cardiovascular Adjustments to Exercising in the Heat or Cold | p. 588 |
Nerve Conduction Velocity | p. 590 |
Muscle-Length Tension Relationship | p. 591 |
Taking SOAP Notes to Evaluate Dietary Supplements | p. 592 |
Body Composition | p. 594 |
Fitness Testing and Activity Monitoring | p. 597 |
Comparison of Fitness Evaluations Between Genders | p. 599 |
Discussing Differential Diagnosis of Chest Pain | p. 602 |
The Relationship Between VO[subscript 2] and Heart Rate During Wheelchair Exercise | p. 604 |
Vector Analysis of the Mean QRS Axis | p. 605 |
Assessment of the Overweight Patient | p. 607 |
Appendices | |
Answers to Summary Knowledge Questions | p. 609 |
Glossary | p. 621 |
Index | p. 639 |
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