Gap Junctions in Development And Disease

by Winterhager, Elke

• ISBN13: 9783540261568
• ISBN10: 3540261567
• Format: Hardcover
• Copyright: 2005-09-15
• Publisher: Springer Verlag

Summary

"The main objective of Gap Junctions in Development and Disease is to describe the molecular events that cause impairments in development and disease. Communication between cells via intercellular channels, so called gap junctions, appears to be essential for certain developmental processes and appropriate organ function. Starting with a comprehensive review of the various mouse and human genes encoding the channel-forming protein connexin, further chapters describe the most important connexin mutations that lead to diseases such as hereditary deafness and female infertility in humans."--BOOK JACKET.

Table of Contents

Connexin and pannexin genes in the mouse and human genome	p. 1
Essential role of gap junctions during development and regeneration of skeletal muscle	p. 13
Connexins in cardiac development : expression, role, and transcriptional control	p. 29
Gap junction and connexin remodeling in human heart disease	p. 57
Gap junction expression in brain tissues with focus on development	p. 83
Connexins responsible for hereditary deafness - the tale unfolds	p. 111
Human connexins in skin development and skin disorders	p. 135
Intercellular communication in lens development and disease	p. 173
Connexin modulators of endocrine function	p. 197
Roles of gap junctions in ovarian folliculogenesis : implications for female infertility	p. 223
Placental connexins of mice and men	p. 239
Connexins in growth control and cancer	p. 253
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