I Basic Principles: How Traits are Transmitted

1 Mendel's Breakthrough: Patterns, Particles, and Principles of Heredity

2 Extension to Mendel for Single-Gene Inheritance

3 The Chromosome Theory of Inheritance

4 Linkage, Recombination, and the Mapping of Genes on Chromosomes

II What Genes Are and What They Do

5 DNA: How the Molecule of Heredity Carries, Replicates, and Recombines Information

6 Anatomy and Function of a Gene: Dissection Through Mutation

7 Gene Expression: The Flow of Genetic Information from DNA via RNA to Protein

III Using Genetic Engineering to Unravel the Information in Genomes

8 DNA at High Resolution: Use of DNA Cloning, PCR, and Hybridization as the Tools of Genetic Analysis

9 The Direct Detection of Genotype

10 The Mapping and Analysis of Genomes

IV How Genes Travel

11 The Eukaryotic Chromosome: An Organelle for Packaging and Managing DNA

12 Chromosomal Rearrangements and Changes in Chromosome Number Reshape Eukaryotic Genomes

13 The Prokaryotic Chromosome: Genetic Analysis in Bacteria

14 The Chromosomes of Organelles Outside the Nucleus Exhibit Non-Mendelian Patterns of Inheritance

V How Genes Are Regulated

15 Gene Regulation in Prokaryotes

16 Gene Regulation in Eukaryotes

17 Cell-Cycle Regulation and the Genetics of Cancer

VI Gene Regulation and Development: Portraits of Model Eukaryotic Organisms

Using Genetics to Study Development: An Introduction to the Genetic Portraits

18 Saccharomyces cerevisiae: A Genetic Portrait of Yeast

19 Arabidopsis Thaliana: Genetic Portrait of A Model Plant

20 Caenorhabditis elegans: Genetic Portrait of a Simple Multicellular Animal

21 Drosophila melanogaster: Genetic Portrait of the Fruit Fly

22 Mus musculus: A Genetic Portrait of the House Mouse

VII How Genes Change

23 The Genetic Analysis of Populations and How They Evolve

24 Evolution at the Molecular Level

Epilogue Human Genetics and the Future of Biology

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