Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods

by Bagchi, Debasis; Lau, Francis; Bagchi, Manashi

• ISBN13: 9780813814025
• ISBN10: 0813814022
• Edition: 1st
• Format: Hardcover
• Copyright: 2010-03-30
• Publisher: Wiley-Blackwell

Summary

This book incorporates the most recent advances in the three major sectors of the field within one volume. Genomics, proteomics, and metobolomics represent scientific research areas that contribute to nutraceutical and functional food research for studies of effectiveness and safety. The nutraceutical and functional food field is rapidly growing in diverse sectors, including academic, commercial and government. It is becoming increasingly evident that genomic research technologies will be increasingly used in the coming years and there is a need to provide resources that will facilitate this growth.

Author Biography

Debasis Bagchi, Ph.D., Pharmacological and Pharmaceutical Sciences Department, College of Pharmacy, University of Houston, TX and President of the American College of Nutrition; Francis Lau, InterHealth USA, Benecia, CA; and Manashi Bagchi, Ph. D., InterHealth USA, Benecia, CA

Table of Contents

Editors and Contributors	p. ix
Preface	p. xiii
Introduction
Recent advances in nutraceuticals and functional foods	p. 3
Novel omics technologies in nutraceutical and functional food research	p. 11
Genomics
Nutrigenomics and statistical power: The ethics of genetically informed nutritional advice	p. 23
NutrimiRomics: The promise of a new discipline in nutrigenomics	p. 35
Genomics in weight loss nutraceuticals	p. 45
Application of genomics and bioinformatics analysis in exploratory study of functional food	p. 61
Genomics as a tool to characterize anti-inflammatory nutraceuticals	p. 73
Application of nutrigenomics in gastrointestinal health	p. 83
Genomics analysis to demonstrate the safety and efficacy of dietary antioxidants	p. 95
Genomics applied to nutrients and functional foods in Japan: State of the art	p. 127
Genomic basis of anti-inflammatory properties of Boswellia extract	p. 155
Nutrigenomic Perspectives on Cancer Chemoprevention with Anti-inflammatory and Antioxidant Phytochemicals: NF-kB and Nrf2 Signaling Pathways as Potential Targets	p. 175
Proteomics
Proteomics analysis of the functionality of Toona sinensis by 2D-gel electrophoresis	p. 201
Application of proteomics in nutrition research	p. 213
Proteomics approach to assess the potency of dietary grape seed proanthocyanidins	p. 225
Proteomics and its application for elucidating insulin deregulation in diabetes	p. 241
Metabolomics
NMR-based-metabolomics strategy for the classification and quality control of nutraceuticals and functional foods	p. 265
Metabolomics: An emerging post-genomic tool for nutrition	p. 271
Evaluation of the beneficial effects of phytonutrients by metabolomics	p. 287
Nutrigenomics in Human Health
Omics for the development of novel phytomedicines	p. 299
Contribution of omics revolution to cancer prevention research	p. 315
Index	p. 329
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