Glial Cells: Their Role in Behaviour

by Edited by Peter R. Laming , Eva Syková , Andreas Reichenbach , Glenn I. Hatton , Herbert Bauer

• ISBN13: 9780521183826
• ISBN10: 0521183820
• Edition: 1st
• Format: Paperback
• Copyright: 2011-02-17
• Publisher: Cambridge University Press

Summary

In mammals the glial (or glue) cells contribute some fifty percent of the volume of the brain. In contrast to the traditional view that they have a purely physically supportive role, research in the past three decades has shown that glia interact morphologically, biochemically, and physiologically with neurons during changes in behavior. The evidence suggests that glia may modulate neuronal activity and thereby influence behavior. This is the first book that describes and discusses these neuronal-glial interactions in relation to behavior. A distinguished set of authors addresses these interactions from a number of viewpoints.

Table of Contents

Preface

Changing concepts on the role of glia

The phylogeny of glial-neuronal relationships and behaviour

Glial cells in brain development and plasticity

The retina as a model of glial function in the brain

Metabolic trafficking between neurons and glia

Transmitter receptor and uptake systems in astrocytes and their relation to behaviour

Glial regulation of the neuronal microenvironment

Role of periaxonal glia in nerve conduction

Transplantation of myelin-forming glial cells into the spinal cord: restoration of normal conduction in previously demyelinated axons

Contributions of potassium currents and glia to slow potential shifts

Acid alkaline transients and pH regulation glia

Intra-cranial slow potential shifts and behavioural state

Slow brain potentials, sensory processing and cognition

Recent evidence from around the brain for structural plasticity of astrocytes in the adult CNS

Astrocytic involvement in learning

References

Index

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