Hereditary Colorectal Cancer: An Issue of Surgical Oncology Clinics of North America

by Gallinger, Steven

• ISBN13: 9781437713909
• ISBN10: 1437713904
• Edition: 1st
• Format: Hardcover
• Copyright: 2009-10-01
• Publisher: SAUNDERS W B CO

Summary

Proposed topics for this issue include: Overview of Colorectal Cancer Genetics; Familial Adenomatous Polyposis; MYH Associated Polyposis; Other genetic colorectal cancer syndromes; Hereditary Nonpolyposis Colorectal Cancer - emphasis on MSH2/MLH1; Hereditary Nonpolyposis Colorectal Cancer - emphasis on PMS2/MSH6; Familial Colorectal Cancer Syndrome Type X; Genome Wide Association Studies and Colorectal Cancer Risk; Genetic Counseling for Hereditary Colorectal Cancer; Genetic Testing for Hereditary Colorectal Cancer; Role of surgery in HNPCC and FAP.

Table of Contents

Foreword	p. xi
Preface	p. xii
Overview of Colorectal Cancer Genetics	p. 573
Familial Adenomatous Polyposis	p. 585
MUTYH-Associated Polyposis and Colorectal Cancer	p. 599
The hMSH2 and hMLH1 Genes in Hereditary Nonpolyposis Colorectal Cancer	p. 611
Role of MSH6 and PMS2 in the DNA Mismatch Repair Process and Carcinogenesis	p. 625
Familial Colorectal Cancer Type X: The Other Half of Hereditary Nonpolyposis Colon Cancer Syndrome	p. 637
Less Common Colorectal Cancer Predisposition Syndromes	p. 647
Genome-Wide Association Studies and Colorectal Cancer	p. 663
Genetic Counseling for Hereditary Colorectal Cancer: Ethical, Legal, and Psychosocial Issues	p. 669
Genetic Testing for Hereditary Colorectal Cancer	p. 687
Role of Surgery in Familial Adenomatous Polyposis and Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome)	p. 705
Index	p. 717
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