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9780896036529

Hormone Resistance Syndromes

by
  • ISBN13:

    9780896036529

  • ISBN10:

    0896036529

  • Format: Hardcover
  • Copyright: 1999-02-01
  • Publisher: Humana Pr Inc

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Summary

Leading clinicians review in depth the clinical and molecular aspects of the hormone resistance syndromes caused by receptor mutations. These mutations are involved in a large number of disorders, including dwarfism, Laron syndrome, pseudohypoparathyroidism, insulin resistance, resistance to thyroid hormone, glucocorticoid resistance, hereditary resistance to vitamin D, and estrogen resistance. Throughout, the book's distinguished contributors not only summarize the clinical features of these and related disorders, but also illuminate their molecular bases. Hormone Resistance Syndromes provides an authoritative summary and standard reference for all those clinicians and researchers actively studying these mutations today and affords a unique opportunity to understand hormone action in normal physiology.

Table of Contents

Preface v(4)
Contributors ix
1 Dwarfism: GHRH Resistance
1(16)
Gerhard Baumann
Hiralal G. Maheshwari
2 Laron Syndrome: Primary Growth Hormone Resistance
17(22)
Zvi Laron
3 Pseudohypoparathyroidism
39(20)
Ali Al-Zahrani
Michael A. Levine
William F. Schwindinger
4 Hereditary Resistance to Vitamin D
59(28)
Peter J. Malloy
David Feldman
5 Decreased Responsiveness to Extracellular Ca^(2+) Owing to Abnormalities in the Ca^(2+)(o)-Sensing Receptor
87(24)
Edward M. Brown
Olga Kifor
Mei Bai
6 Resistance to TSH
111(34)
Peter Kopp
7 Thyroid Hormone Resistance
145(20)
V. Krishna K. Chatterjee
Roderick J. Clifton-Bligh
Mark Gurnell
8 Diabetes Mellitus: Insulin Resistance
165(20)
Simeon I. Taylor
Elif Arioglu
9 LH Insensitivity Syndrome
185(12)
Axel P.N. Themmen
John W. M. Martens
Han G. Brunner
10 FSH Resistance
197(12)
Kristina Aittomaki
Ilpo T. Huhtaniemi
11 Genetic Alterations of Androgen Receptor Function
209(24)
Ken Brantley
Tianshu Gao
Michael J. McPhaul
12 Retained Mullerian Ducts: AMH Resistance Syndrome
233(12)
Nathalie Josso
Jean-Yves Picard
Rodolfo Rey
13 Adrenal Insufficiency: ACTH Resistance
245(14)
Adrian J. L. Clark
14 Glucocorticoid Resistance and Hypersensitivity
259(14)
Denis P. Franchimont
George P. Chrousos
Index 273

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