Immunology : A Short Course

by Coico, Richard; Sunshine, Geoffrey

• ISBN13: 9780470081587
• ISBN10: 0470081589
• Edition: 6th
• Format: Paperback
• Copyright: 2009-01-14
• Publisher: Wiley-Blackwell

Summary

Immunology: A Short Course, Sixth Edition introduces all the critical topics of modern immunology in clear and succinct yet comprehensive fashion. The authors offer a uniquely balanced coverage of classical and contemporary approaches, basic and clinical aspects. As with the previous editions, the strength of the text is in a complete review of modern immunology without burdening the reader with excessive data or theoretical discussions. Each chapter is divided into short, self-contained units that address key topics illustrated by uniformly drawn, full-color illustrations, many brand new to this edition. The sixth edition of this successful textbook newly covers: Toll-like receptors, their ligands and intracellular activation pathways The key role of activation induced cytidine deaminase (AID) in somatic hypermutation and class switch recombination. The autoimmune regulator (AIRE) gene in self-tolerance and autoimmunity T and B cell activation and the immunological synapse, as well as characterization and mechanisms of action of T regulatory cellsPraise for the previous edition:"This book is clearly a precious resource for undergraduate, graduate and medical students alike... For those who need an introduction to the fascinating world of immunology, this book should most certainly spark the interest." ANNALS OF BIOMEDICAL ENGINEERING"... an excellent beginner's guide... the authors have done a terrific job of providing an overview of the field." YALE JOURNAL OF BIOLOGY AND MEDICINE

Author Biography

Dr. Richard Coico is Professor and Chairman of the Department of Microbiology and Immunology and Dean at the City University of New York Medical School. He directs CUNY Microbiology and Immunology courses and also participates directly in the teaching of immunology to graduate students. 

Dr. Sunshine is a Senior Scientist at the Health Effects Institute in Cambridge, Massachusetts. He is also a lecturer in the Department of Pathology at Tufts University School of Medicine.

Table of Contents

About the Authors

Contributors

Preface and Acknowledgments

Overview of the Immune System

Elements of Innate and Acquired Immunity

Immunogens and Antigens

Antibody Structure and Function

Antigen-Antibody Interactions, Immune Assays, and Experimental Systems

The Genetic Basis of Antibody Structure

Biology of the B Lymphocyte

The Role of the Major Histocompatibility Complex in the Immune Response

Biology of the T Lymphocyte

Activation and Function of T and B Cells

Cytokines

Tolerance and Autoimmunity

Complement

Hypersensitivity: Type I

Hypersensitivity: Types II and III

Hypersensitivity: Type IV

Immunodeficiency Disorders and Neoplasias of the Lymphoid System

Transplantation

Tumor Immunology

Resistance and Immunization to Infectious Diseases

Glossary

Appendix

Index

Table of Contents provided by Publisher. All Rights Reserved.