Infertility in the Male

by Edited by Larry I. Lipshultz , Stuart S. Howards , Craig S. Niederberger

• ISBN13: 9780521872898
• ISBN10: 0521872898
• Edition: 4th
• Format: Hardcover
• Copyright: 2009-10-30
• Publisher: Cambridge University Press

Summary

The new edition of this canonical text on male reproductive medicine will cement the book's market-leading position. Practitioners across many specialties - including urologists, gynecologists, reproductive endocrinologists, medical endocrinologists and many in internal medicine and family practice - will see men with suboptimal fertility and reproductive problems. The book provides an excellent source of timely, well-considered information for those training in this young and rapidly evolving field. While several recent books provide targeted 'cookbooks' for those in a male reproductive laboratory, or quick reference for practising generalists, the modern, comprehensive reference providing both a background for male reproductive medicine as well as clinical practice information based on that foundation has been lacking until now. The book has been extensively revised with a particular focus on modern molecular medicine. Appropriate therapeutic interventions are highlighted throughout.

Author Biography

Larry I. Lipshultz is Professor and Chief of the Division of Male Reproductive Medicine and Surgery, Scott Department of Urology, Baylor College of Medicine, Houston, TX, USA. Stuart S. Howards is Professor of urology and Molecular Physiology and Biological physics at the University of Virginia, Charlottesville, VA, USA. Craig S. Niederberger is the Clarence C. Saelhof Professor of Urology and Chairman of the Department of Urology at the University of Illinois at Chicago, IL, USA.

Table of Contents

List of contributors	p. vii
Foreword	p. xi
Anatomy and embryology of the male reproductive tract and gonadal development	p. 1
Male hypothalamic-pituitary-gonadal axis	p. 14
Leydig cell development and function	p. 29
The Sertoli cell: morphology, function, and regulation	p. 48
Spermatogenesis in the adult	p. 74
The epididymis and accessory sex organs	p. 90
An overview of the molecular mechanisms involved in human fertilization	p. 104
New concepts in the genetics of male reproduction and infertility	p. 122
Erection, emission, and ejaculation: mechanisms of control	p. 132
Office evaluation of the subfertile male	p. 153
Evaluation of sperm function	p. 177
Endocrine evaluation	p. 199
Testicular biopsy in male infertility evaluation	p. 215
Adverse effects of environmental chemicals and drugs on the male reproductive system	p. 226
Genetic aspects of infertility	p. 251
Immunologic infertility	p. 277
The effect of genital tract infection and inflammation on male infertility	p. 295
Varicocele	p. 331
Evaluation of female infertility for the non-gynecologist	p. 362
The use of ultrasound and radiologic imaging in the diagnosis of male infertility	p. 375
Microsurgical treatment of male infertility	p. 392
Techniques of sperm retrieval	p. 407
Management of ejaculatory duct obstruction	p. 421
Nonsurgical treatment of male infertility: specific therapy	p. 430
Nonsurgical treatment of male infertility: empiric therapy	p. 438
Abnormalities of ejaculation	p. 454
Male contraception and vasectomy	p. 474
Intrauterine insemination from the urologist's perspective	p. 493
In-vitro fertilization and micromanipulation for male infertility	p. 500
Psychological issues of infertility and assisted reproductive technology	p. 516
Legal issues in fertility preservation in the male	p. 528
Analyzing male fertility data	p. 541
Semen analysis	p. 550
Strict criteria for sperm morphology	p. 574
Sperm processing techniques	p. 582
Sperm banking: indications and techniques	p. 593
Tests for antisperm antibodies	p. 603
Semen white blood cell assay	p. 613
Determination of seminal oxidants (reactive oxygen species)	p. 618
Measurement of DNA fragmentation in human spermatozoa	p. 633
A look towards the future: advances in andrology expected to revolutionize the diagnosis and treatment of the infertile male	p. 642
Index	p. 654
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