The Laboratory Rat

by Suckow; Weisbroth; Franklin

• ISBN13: 9780120749034
• ISBN10: 0120749033
• Edition: 2nd
• Format: Hardcover
• Copyright: 2005-12-07
• Publisher: Elsevier Science

Summary

This second edition features updated information on a variety of topics including: rat genetics and genomics, both spontaneous and induced disease; state-of-the-art technology for housing and husbandry; occupational health, and experimental models. A premier source of information on the laboratory rat that will be of interest to veterinary and medical students, senior graduate, graduate students, post-docs and researchers who utilize animals in biomedical research.

Table of Contents

List of Contributors	vii
Preface	xi
Foreword	xiii
Historical Foundations	1	(52)
J. Russell Lindsey
Henry J. Baker
Ethical and Legal Perspectives	53	(18)
Beverly J. Gnadt
Taxonomy and Stocks and Strains	71	(22)
Hans J. Hedrich
Morphophysiology	93	(34)
John Hofstetter
Mark A. Suckow
Debra L. Hickman
Clinical Pathology of the Rat	127	(20)
Bruce D. Car
Vicki M. Eng
Nancy E. Everds
Denise I. Bounous
Reproduction and Breeding	147	(18)
Jeffrey J. Lohmiller
Sonya P. Swing
Assisted Reproductive Technologies and Genetic Modifications in Rats	165	(26)
Yuksel Agca
John K. Critser
Analysis of Behavior in Laboratory Rats	191	(28)
Ian Q. Whishaw
Forrest Haun
Valerie Bergdall
Bryan Kolb
Nutrition	219	(84)
Sherry M. Lewis
Duane E. Ullrey
Dennis E. Barnard
Joseph J. Knapka
Housing and Environment	303	(36)
Robert E. Faith
Jack R. Hessler
Bacterial, Mycoplasmal and Mycotic Infections	339	(84)
Steven H. Weisbroth
Dennis F. Kohn
Ron Boot
Viral Disease	423	(30)
Robert O. Jacoby
Diane J. Gaertner
Parasitic Diseases	453	(26)
David G. Baker
Neoplastic Disease	479	(34)
Gary A. Boorman
Jeffrey I. Everitt
Metabolic, Traumatic, and Miscellaneous Diseases	513	(34)
William W. King
Steven P. Russell
Medical Management and Diagnostic Approaches	547	(18)
Glen Otto
Craig L. Franklin
Occupational Health and Safety	565	(22)
Sanford H. Feldman
David N. Easton
Experimental Modeling and Research Methodology	587	(40)
Michael A. Koch
Anesthesia and Analgesia	627	(38)
George A. Vogler
Euthanasia and Necropsy	665	(14)
Jeffrey I. Everitt
Elizabeth A. Gross
Integrating Biology with Rat Genomic Tools	679	(14)
Carol Moreno-Quinn
Howard J. Jacob
Gnotobiotics	693	(18)
Philip B. Carter
Henry L. Foster
Spontaneous, Surgically and Chemically Induced Models of Disease	711	(22)
Dwight R. Owens
The Nude Rat	733	(28)
Martha A. Hanes
Gerontology and Age-Associated Lesions	761	(12)
Nancy L. Nadon
Cardiovascular Research	773	(30)
Peter G. Anderson
Sanford P. Bishop
J. Thomas Peterson
Toxicology	803	(14)
Thomas E. Hamm
Mary Ann Vasbinder
Angela King-Herbert
Embryology and Teratology	817	(30)
Carol Erb
Immunology	847	(18)
Veronica Jennings
Dirck Dillehay
Wild and Black Rats	865	(18)
Marc Hulin
Robert Quinn
Appendix	883	(2)
Subject Index	885