Liver Disease in Children

by Suchy, Frederick J.; Sokol, Ronald J.; Balistreri, William F.

• ISBN13: 9780781720984
• ISBN10: 0781720982
• Edition: 2nd
• Format: Hardcover
• Copyright: 2000-12-18
• Publisher: LWW

Summary

This is the definitive book on pediatric liver disease, providing extensive, well-edited information that is not easily accessible or available in other textbooks. Read comprehensive information explaining the pathophysiology, clinical and laboratory diagnosis and clinical manifestations of liver disease. A must-have for those interested in this rapidly growing subspecialty in pediatrics. A Brandon-Hill recommended title.

Table of Contents

Contributing Authors	ix
Preface to the First Edition	xiii
Preface	xv
SECTION I: PATHOPHYSIOLOGY OF PEDIATRIC LIVER DISEASE	1	(152)
Structural and Functional Development of the Liver	3	(20)
Saul J. Karpen
Frederick J. Suchy
Mechanisms and Morphology of Cholestasis	23	(16)
M. James Phillips
Frederick J. Suchy
The Cholangiopathies	39	(24)
Valeer J. Desmet
Fulminant Hepatic Failure in Children	63	(26)
Peter F. Whitington
Humberto E. Soriano
Estella M. Alonso
Cirrhosis and Chronic Liver Failure	89	(40)
Stephen Hardy
Ronald E. Kleinman
Portal Hypertension	129	(24)
Benjamin L. Shneider
SECTION II: EVALUATION OF LIVER DISEASE	153	(32)
Laboratory Assessment of Liver Function and Injury in Children	155	(16)
L. Arturo Batres
Eric S. Maller
Laboratory Diagnosis of Inborn Errors of Metabolism	171	(14)
Piero Rinaldo
SECTION III: CHOLESTATIC LIVER DISEASES	185	(178)
Approach to the Infant with Cholestasis	187	(8)
Frederick J. Suchy
Medical and Nutritional Management of Cholestasis	195	(44)
Andrew P. Feranchak
Rebecca O. Ramirez
Ronald J. Sokol
Neonatal Hepatitis and Congenital Infections	239	(14)
Philip Rosenthal
Biliary Atresia and Other Disorders of the Extrahepatic Bile Ducts	253	(22)
William F. Balistreri
Kevin E. Bove
Frederick C. Ryckman
Neonatal Jundice and Disorders of Bilirbin Metabolism	275	(40)
Glenn R. Gourley
Familial Hepatocellular Cholestasis	315	(12)
Peter F. Whitington
Karan McBride Emerick
Frederick J. Suchy
Alagille Syndrome	327	(16)
David A. Piccoli
Diseases of the Gallbladder in Infancy, Childhood, and Adolescence	343	(20)
James E. Heubi
L. Glenn Lewis
John F. Pohl
SECTION IV: HEPATITIS AND IMMUNE DISORDERS	363	(140)
Acute and Chronic Viral Hepatitis	365	(64)
Nada A. Yazigi
William F. Balistreri
Autoimmune Hepatitis	429	(14)
Fernando Alvarez
Sclerosing Cholangitis	443	(20)
Jane P. Balint
William F. Balistreri
Drug-Induced Liver Disease	463	(30)
Eve A. Roberts
Immune Deficiency and Liver Disease	493	(10)
Harland S. Winter
SECTION V: METABOLIC LIVER DISEASE	503	(340)
Approach to the Child with Metabolic Liver Disease	505	(18)
Harvey L. Sharp
α1-Antitrypsin Deficiency	523	(26)
David H. Perlmutter
The Liver and Biliary Tract in Cystic Fibrosis	549	(16)
Kevin J. Gaskin
Inborn Errors of Carbohydrate Metabolism	565	(30)
Fayez K. Ghishan
Martha P. Ballew
Copper and Iron Storage Disorders	595	(46)
Ronald J. Sokol
Michael R. Narkewicz
Neonatal Hemochromatosis	641	(8)
Delphine de Boissieu
A. S. Knisely
Porphyrins and Porphyria	649	(18)
Deborah K. Freese
Tyrosnemia	667	(20)
Grant A. Mitchell
Pierre A. Russo
Josee Dubois
Fernando Alvarez
The Lysosomal Storage Diseases	687	(14)
Margaret M. McGovern
Pramod K. Mistry
Disorders of Bile Acid Synthesis and Metabolism: A Metabolic Basis for Liver Disease	701	(34)
Kenneth D. R. Setchell
Nancy C. O'Connell
Inborn Defects in Mitochondrial Fatty Acid Oxidation	735	(52)
William R. Treem
Mitochondrial Hepatopathies	787	(24)
Ronald J. Sokol
William R. Treem
Peroxisomal Diseases	811	(16)
Paul A. Watkins
Kathleen B. Schwarz
Disorders of the Urea Cycle	827	(16)
Michael T. Geraghty
Saul W. Brusilow
SECTION VI: OTHER CONDITIONS AND ISSUES IN PEDIATRIC HEPATOLOGY	843	(132)
Bacterial, Parasitic, and Fungal Infections of the Liver	845	(24)
Donald A. Novak
Gregory Y. Lauwers
David J. Dolson
Systemic Disease and the Liver	869	(30)
Michael K. Farrell
John C. Bucuvalas
Fibrocystic Liver Disease	899	(16)
Maureen M. Jonas
Antonio R. Perez-Atayde
Hepatic Tumors in Children	915	(34)
J. Thomas Stocker
Liver Transplantation in Children	949	(26)
Frederick C. Ryckman
Maria H. Alonso
John C. Bucuvalas
William F. Balistreri
Subject Index	975