Lower Extremity Arterial Disease

by Caralis, Dennis G.; Barkis, George L., M.D.; Bakris, George L.

• ISBN13: 9781588295545
• ISBN10: 1588295540
• Format: Hardcover
• Copyright: 2005-03-01
• Publisher: Humana Pr Inc

Summary

A comprehensive review the state-of-the-art in atherosclerosis of the arteries of the legs and feet. The authors discuss in detail the primary symptom-claudication-an intermittent pain in the leg or foot while walking, its predisposing factors, the current diagnostic methodologies, the impressive advances in the therapeutic armamentarium, and the need to screen for co-existing coronary artery disease. Additional chapters describe cutting-edge noninvasive angiography and vascular flow studies, specific drug therapy for claudication, regression of atherosclerosis therapy, gene therapy, and drug eluting stents for peripheral arterial disease. The authors also examine the epidemiology of LEAD, the effects of smoking and effective smoking cessation programs, its pathogenesis and its association with lipid abnormalities and hypertension, aggressive risk factor modification, and the need to measure the ankle brachial index of every patient over 45.

Table of Contents

Series Editor's Introduction	v
Preface	vii
Contributors	xiii
1 Claudication: Clinical Diagnosis and Differential Diagnosis	1	(22)
Dennis G. Caralis
2 Noninvasive Diagnostic Evaluation of Peripheral Arterial Disease	23	(16)
Nicos Labropoulos and Apostolos K. Tassiopoulos
3 Smoking and Smoking Cessation	39	(14)
Albert J. Bellg and Aristdis N. Mavridis
4 Peripheral Arterial Disease and Diabetes	53	(8)
George L. Bakris
5 Hyperlipidemia in Peripheral Arterial Disease	61	(14)
Ambika Babu, C.R. Kannan, and Theodore Mazzone
6 Hypertension and Peripheral Vascular Disease	75	(10)
Anjula Gandhi, Jay Garg, and George L. Bakris
7 Physical Inactivity is a Risk Factor for Lower Extremity Arterial Disease and Coronary Heart Disease	85	(14)
Dennis G. Caralis and Stamatis Dimitropoulos
8 Pathogenesis of Atherosclerotic Vascular Disease	99	(84)
Bassem Jamil Basha, George L. Bakris, and James R. Sowers
9 Lower Extremity Arterial Disease Co-Existing With Coronary Artery Disease	183	(40)
Dennis G. Caralis
10 Medical Therapy of Claudication and Lower Extremity Arterial Disease	223	(20)
Dennis G. Caralis
11 Exercise Therapy for Lower Extremity Arterial Disease	243	(14)
Peter F. Kokkinos
12 Endovascular Strategies for Management of Claudication and Lower Extremity Arterial Disease	257	(12)
Michael C. Brunner and Dennis G. Caralis
13 Severe Lower Extremity Arterial Disease: Limb Salvage and Revascularization	269	(24)
Chad E. Jacobs and Walter J. McCarthy
Index	293