Managing Breast Cancer Risk

by Morrow, Monica; Jordan, V. Craig

• ISBN13: 9781550092608
• ISBN10: 155009260X
• Edition: CD
• Format: Hardcover
• Copyright: 2003-10-01
• Publisher: Pmph USA Ltd

Summary

Managing Breast Cancer Risk is a single source for information needed by primary care physicians, nurses, gynecologists, as well as oncologic specialists who deal with women who are concerned about breast cancer. Its purpose is to bring together a multidisciplinary group of experts to address breast cancer risk in a clinically meaningful way. Chapters providing detailed information on individual risk factors are accompanied by a discussion of models, which integrate multiple factors for a more complete assessment of risk. Traditional strategies for risk management, including surveillance and prophylactic surgery, are reviewed, and the data on newer techniques such as ductal lavage and screening with magnetic resonance is presented. The rational for chemoprevention with selective estrogen receptor modulators (SERMS) is discussed, and the evidence for tamoxifen as a chemopreventative is updated. The potential for chemoprevention with newer SERMS and the aromatase inhibit

Table of Contents

Preface	p. vii
Contributors	p. xiii
Evaluation of Risk
Overview of Clinical Risk Assessment	p. 3
Familial and Genetic Risk	p. 26
Endocrine Risk Factors	p. 43
Benign Breast Disease and Breast Cancer Risk	p. 57
Lifestyle, Environmental Factors, and Breast Cancer Risk	p. 70
Breast Cancer Risk in the Context of Overall Health	p. 80
Risk Management Strategies
Surveillance
Outcome of Routine Surveillance of the High-Risk Woman	p. 103
Newer Imaging Approaches to the High-Risk Woman	p. 116
Role of Breast Epithelial Sampling Techniques in High-Risk Women	p. 138
Chemoprevention
Biologic Basis for Breast Cancer Risk Reduction with Pharmacologic Agents	p. 159
Tamoxifen for Chemoprevention	p. 175
SERMs Other Than Tamoxifen for Chemoprevention	p. 186
Aromatase Inhibitors for Chemoprevention	p. 199
Quality of Life Issues with Endocrine Chemoprevention	p. 214
Improving Quality of Life for Women at High Risk for Breast Cancer: Symptom Management without Estrogen	p. 227
Surgical Prevention
Prophylactic Mastectomy and Oophorectomy	p. 241
Breast Reconstruction	p. 259
Practical Management Guidelines
Practical Management Guidelines	p. 289
Index	p. 294
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