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This book focuses on modeling electrokinetic phenomena, including electroosmosis, electrophoresis, and dielectrophoresis in micro- and nanofluidic devices, which play important roles in facilitating fluid transport and particle manipulation in micro- and nanofluidic devices. These have the potential to improve and reduce the cost of healthcare around the globe and revolutionize chemical and biological analysis by integrating and automating sophisticated diagnostic procedures in micro/nanofluidic devices. This high-level treatment offers an essential guide for researchers and advanced students in nanotechnology, mechanical engineering, and colloid science.