Mohs Surgery and Histopathology: Beyond the Fundamentals

by Edited by Ken Gross , Howard K. Steinman

• ISBN13: 9780521888042
• ISBN10: 0521888042
• Edition: 1st
• Format: Hardcover
• Copyright: 2009-06-08
• Publisher: Cambridge University Press

Summary

Mohs surgery is a highly effective treatment for certain cutaneous and oral pharyngeal cancers. The procedure allows for the precise and complete removal of cancers while preserving significant amounts of normal tissue. Through the presentation and orientation of the specimens' complete surgical margin on pathology slides, the location of tumor foci and other relevant findings can be correlated with their locations on the surgical wound. The ability to create perfect slides for histological examination lies at the core of effective Mohs surgery. These procedures have a 99 percent cure rate for certain cancers when implemented correctly. This book describes the methods the dermatologist, pathologist, or technician can use to optimize the Mohs technique and produce the highest-quality slides and highest cure rates possible.

Table of Contents

Microscopy and Tissue Preparation

Introduction

How to excise tissue for optimal sectioning

Optimizing the Mohs microscope

Tissue preparation and chromacoding

Embedding techniques

Introduction to Lab Tech Techniques

Lab pearls: how to make great slides and preparing slides with cartilage

Lab pearls: staining, inking, and coverslipping

Lab pearls: troubleshooting slide quality

Mohs slide organization and standardization for effective interpretation

Mohs mapping

Microanatomy and Neoplastic Disease

Normal microanatomy: vertical & horizontal

Basal cell carcinoma: vertical and horizontal

Squamous cell carcinoma: vertical and horizontal

Unusual tumors: vertical and horizontal

Mohs for melanoma

Perineural tumors

Special Techniques and Stains

Fixed tissue

Tol blue

Forms and templates for Mohs surgery

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