Nausea Mechanisms and Management

by Stern, R. M.; Koch, Kenneth L.; Andrews, Paul

• ISBN13: 9780195178159
• ISBN10: 0195178157
• Format: Hardcover
• Copyright: 2011-02-18
• Publisher: Oxford University Press

Summary

Nausea is a complex sensation that results from the interaction of certain fixed biological factors, such as gender, with changeable psychological factors, such as anxiety. This is the first book to provide a complete, in-depth explanation of what we know about nausea, along with the latest research results on its causes and treatment. As it is the product of long-term collaboration between scientists from the three main approaches to studying and treating nausea--psychology, gastroenterology, and physiology--the information this book provides is both comprehensive and well integrated. The book is divided into two parts, on mechanisms and management, respectively, and four sections. The chapters in Section I introduce the concept of nausea as a protective control mechanism with individual dynamic thresholds, explain the function of nausea, review past and present conceptions of nausea, and describe the prevalence of nausea in different conditions. Section II includes four basic chapters that review what is known about the physiological bases of nausea. Other chapters explore the roles of the central nervous system, autonomic nervous system, endocrine system, and gastric dysrhythmias. Section III presents the difficult problem of measuring nausea, with chapters focusing on measuring nausea in humans and studying it in animals. Section IV forms the second part of the book, on the management of nausea. The main chapters cover nausea and its treatment in several conditions, including chronic nausea, diabetes, pregnancy, post-operative, cancer and its treatment, and provocative motion. A final chapter discusses future research, including three preliminary studies of novel treatment approaches.

Table of Contents

Mechanisms
Present and Past Concepts of Nausea, Prevalence, and Function
Nausea: Definitions, History, and Function	p. 3
Prevalence of Nausea from Various Causes	p. 17
Nausea as a Protective Control Mechanism with a Dynamic Threshold	p. 29
Physiology of Nausea
The Central Nervous System and Nausea	p. 39
The Autonomic Nervous System and Nausea	p. 77
The Endocrine System and Nausea	p. 115
Gastric Dysrhythmias and Nausea	p. 153
Measurement of Nausea
The Functions, Identification, and Measurement of Nausea and Related Behaviors in Animals	p. 171
The Measurement of Nausea in Humans	p. 241
Management
Diagnosis and Management of Acute and Chronic Nausea	p. 253
Nausea of Diabetes	p. 269
Nausea During Pregnancy	p. 283
Postoperative Nausea	p. 305
Nausea Resulting from Cancer and Its Treatment	p. 315
Nausea of Motion Sickness	p. 331
Future Research: Management and Mechanisms	p. 355
References	p. 361
Author Index	p. 433
Subject Index	p. 449
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